PEGylated Nanocarriers in Medicine and Pharmacy

This book shelters the central principles, cutting-edge methodologies, and incipient thought processes applied to PEGylation research. The content also expounds on the critical properties of PEG and other polymers that can be applied to formulate a prolonged-circulating nanocarrier system for the delivery of gene, nucleic acid, drugs, protein, and peptide and diagnostic agents. The book summarizes the methodologies and effects of PEGylation on drug delivery and highlights recent developments in PEGylated drugs. It also aims to present vital biopharmaceutical fates of PEGylated therapeutics and examines the approaches involved in the preparation, physicochemical properties, and biological applications of long-circulating PEGylated pharmaceutical nanocarriers. This book also cross-talks and offers expert viewpoints on mucus-penetrating PEGylated nanocarrier, reversible PEGylation of nanocarriers, and Bio-PEGylation as well as PEGylation and its alternatives. The book also deals with hottopics including the current status and regulatory aspects of PEGylated Nanoproducts, and medicinal and pharmaceutical applications of PEGylated Nanocarriers. The book provides a comprehensive literature resource for the students, biologists, chemists, toxicologists, medical researchers, scientists in industries, research institutes, universities, and consultants involved in the development and testing of new advanced medicines

Dr. Rakesh K Tekade is renowned academician and researcher with more than 15 years of teaching and research experience. He is currently associated as an Associate Professor of Pharmaceutics at National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad (Institute of National Importance, Govt. of India). He earned his Doctoral degree from the Dr. H.S. Gour Central University (India) as a split-site commonwealth fellow at University of Central Lancashire-UK. He has received Postdoctoral trainings in The University of Texas Southwestern Medical Center, USA and The University of Hawaii, USA. Recipient of several acclaimed awards, including Commonwealth Fellow- UK, National Doctoral Fellow (AICTE-NDF), IRISH Government Postdoctoral Award (IRISH-PDF), and CSIR Senior research fellowship (CSIR-SRF), India and Junior Research Fellowship, India (AICTE-JRF) award. He is a recipient of Commonwealth Fellowship (University of Central Lancashire, Preston, UK) as well as has industrial experience (R & D, Ranbaxy Pharmaceuticals, India). Dr Tekade bears an explicit experience of teaching various modules for Ph. D, Masters & Bachelors students in Universities based in USA, UK, Malaysia, & India. His current research involves development of fit-to-purpose, translational, and novel targeted specific nano-biomaterials for biomedical applications. He has co-authored more than 300 publications and has edited 10 reference books and 12 Patent applications. Dr Tekade has served as a member of various Institution committees, including the Board of Studies and Research, Research advisory committee, Equipment purchase committee, Senate committee, Placement committee, Grant reviewer for the FONDECYT FUNDS (Chile), National Science Centre (Poland); French National Research Agency (ANR) France, Khwarizmi International Award (KIA) (Iran). He has been listed as Top 2% researcher in the field of Pharmacy and Pharmacology, by Stanford University, USA. Also, listed as Top 2% world scientist by the database recently published by Elsevier.

Prof. Jain is an internationally renowned academician and researcher and a senior professor in India who superannuated his services after rendering more than 40 years of dedicated and distinguished service as a teacher and 25 years as full professor. Starting his academic career in 1973 he worked as Lecturer in Pharmacy, Holkar College, Indore; Reader in Pharmaceutical Technology. M.S. University, Baroda; Professor and Principal, College of Pharmacy, Nasik; Professor and Head, Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar; Principal, College of Pharmacy, New Delhi; Visiting Professor, Dubai Pharmacy College, Dubai (UAE); and Head, Pharmacy Department, Delhi University. Subsequent to his superannuation, Prof. Jain rendered his services as Director, ISF College of Pharmacy, Moga, Punjab, India) and as Emeritus Fellow (U.G.C.) at Rajiv Gandhi Technological University, Bhopal, M.P., India. Prof. Jain has rendered services as experts at NAAC, NBA, Selection committees of several universities, PSC, UPSC, UGC, AICTE etc. Prof. Jain is a popular speaker at conferences, seminars, Faculty Development Programmes and Quality Improvement programmes and he has extensively travelled abroad. Prof. Jain is the author of two dozen celebrated books in pharmaceutical sciences including a series on controlled and novel drug delivery systems. He has to his credit over 500 publications in reputed pharmaceutical Journals and has supervised 55 PhD and 142 M. Pharm. candidates.