Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists

Daniel Sigg

ISBN 10: 383835379X / ISBN 13: 9783838353791

Edité par LAP LAMBERT Academic Publishing, 2010

A propos de cet article

Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists | Daniel Sigg | Taschenbuch | 208 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838353791 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

N° de réf. du vendeur 101216148

Détails bibliographiques

• Titre: Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists
• Éditeur: LAP LAMBERT Academic Publishing
• Date de parution: 2010
• Langue: anglais
• ISBN à 10 chiffres: 383835379X
• ISBN à 13 chiffres: 9783838353791
• Reliure: Taschenbuch
• État de l'article: Neu
• Dimensions: 220 L x 150 H x 13 P (en millimètres) 220 millimètres de largeur par 150 millimètres de hauteur par 13 millimètres de profondeur
• Poids: 328 grammes
• Catalogues du vendeur:
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Synopsis

The objective of this research was to investigate the role of opioids in myocardial protection of the large mammalian heart. A porcine isolated working heart model of swine was carefully characterized and various opioid agonists were administered prior to inducing global ischemia. An acute coronary occlusion model was developed to investigate the effects of opioid preconditioning on regional ischemia, in particular infarct size, myocardial function, and arrhythmias. The results of these studies suggest a specific role of δ-receptor agonists in myocardial protection in large mammalian hearts.