Quadruplex Nucleic Acids

ISBN 10: 0854043748 / ISBN 13: 9780854043743

Edité par Royal Society Of Chemistry Okt 2006, 2006

A propos de cet article

Neuware - Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability. The biology of quadruplexes and G-rich genomic regions and G-quartets in supramolecular chemistry and nanoscience are also considered. Surveying the current state of knowledge, and with contributions from leading experts, this is the first comprehensive review of this rapidly growing area. Quadruplex Nucleic Acids is ideal for researchers interested in areas related to chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology.

N° de réf. du vendeur 9780854043743

Détails bibliographiques

• Titre: Quadruplex Nucleic Acids
• Éditeur: Royal Society Of Chemistry Okt 2006
• Date de parution: 2006
• Langue: anglais
• ISBN à 10 chiffres: 0854043748
• ISBN à 13 chiffres: 9780854043743
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 242 L x 162 H x 24 P (en millimètres) 242 millimètres de largeur par 162 millimètres de hauteur par 24 millimètres de profondeur
• Poids: 638 grammes

A propos de ce titre

Synopsis

Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability.