Redox-Responsive Delivery Systems : Principles, Advances and Applications

In the era of precision medicine, the demand for smart and targeted drug delivery technologies is greater than ever. Redox-responsive delivery systems represent a cutting-edge approach that exploits the unique oxidative and reductive environments of diseased tissues to achieve site-specific therapeutic action.

This comprehensive volume brings together foundational knowledge, recent innovations, and application-specific insights into redox-sensitive systems used for drug, gene and vaccine delivery. The book covers a wide range of carriers—including polymersomes, liposomes, nanoparticles, micelles, prodrugs and dendrimers—highlighting their utility across various therapeutic landscapes, including cancer, neurodegenerative diseases, metabolic disorders, infectious diseases and gene editing platforms like CRISPR-Cas9.

Key Features:

• Explores the principles and design of redox-responsive materials
• Covers disease-specific applications, including Alzheimer’s, Parkinson’s, diabetes and antimicrobial resistance
• Discusses innovative delivery systems for siRNA and genome editing
• Addresses industrial translation, scale-up and commercialization challenges
• Authored by leading experts in pharmaceutics, nanomedicine and biomedical engineering

Ideal for pharmaceutical scientists, nanotechnologists, biomedical researchers and healthcare innovators, this book serves as a definitive guide to one of the most promising frontiers in drug delivery science.

Harness redox biology to revolutionize how therapeutics are delivered—safely, smartly and effectively.

Durgesh Nandini Chauhan has completed her B. Pharm degree in Pharmacy from the Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India and her M. Pharm in pharmaceutics from Uttar Pradesh Technical University, currently known as Dr. A.P.J. Abdul Kalam Technical University, Lucknow in 2006. She is presently working as Assistant Professor in Columbia Institute of Pharmacy, Raipur, Chhattisgarh, India. She has 16 years of academic (teaching) experience from Institutes of India in pharmaceutical sciences. She taught subjects such as pharmaceutics, pharmacognosy, traditional concepts of medicinal plants, drug-delivery phytochemistry, cosmetic technology, pharmaceutical engineering, pharmaceutical packaging, quality assurance, dosage form designing and anatomy and physiology. She is member of Association of Pharmaceutical Teachers of India (APTI), SILAE: Società Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), and so forth. She has written more than 10 publications in national and international journals, 15 book chapters, and editor in 10 books. She is also active as a reviewer for several international scientific journals and active participant in national and international conferences.

Shraddha Manish Gupta has more than 18 years of research and teaching experience and currently is an Assistant Professor-SG at School of Health Sciences and Technology, UPES, Dehradun, India. She has completed B. Pharm and M. Pharm from NDMVP’S College of Pharmacy, Nasik (M.H.) in 2003, 2006 respectively and Ph.D. from Oriental University Indore, India. She Secured 96 percentile in GATE-2004 conducted by IIT, Delhi. She worked as a Research Assistant in School of Pharmacy, Monash University, Malaysia. She was Mentor in CSIR-SRTP (2020) program under Interdisciplinary Approach for Sustainable Use of Resources project-13. She has written more than 10 articles published in Q1 international journals, 2 patents (1 granted, 1published), one edited book with CRC publisher and 12 book chapters. She is a member of various professional and academic bodies like, Life Membership of Association of Pharmaceutical Teachers of India (APTI), Indian Pharmaceutical Association (IPA) and Indian Society of Chemists and Biologists (ISCB).

Kamal Shah has more than 18 years of research and teaching experience and currently working as Professor at the Institute of Pharmaceutical Research, GLA University, Mathura, India. He completed B. Pharm from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P.) in 2003. He was gold medalist in B. Pharm, M.Pharm. from the Department of Pharmaceutical Sciences, Sagar University, Sagar, India and PhD from APJ Kalam University Lucknow, India. He has written more than 90 articles published in national and international journals, 20 book chapters and 5 edited books. His SCOPUS h index is 17, with 905 citations.

Kamta Prasad Namdeo (M. Pharm, PhD, FIC) Professor (Pharmaceutical Chemistry) Department of Pharmacy Guru Ghasidas Vishwavidyalaya (A Central University) Bilaspur (CG). He has 28 years of Research and Academic Experience. He has taught at BMCP Pilani (Raj), BRNCP Mandsaur (MP) and IOP Bundelkhand University Jhansi (UP). He has completed three research project funded by UGC, AICTE and AYUSH, published two books, 10 book chapters, 7 Indian patent and 90 research papers in various National and International journals. He has presented more than 60 research papers invited Lectures and Chair the session in various National, International conferences. Four Ph.D and 40 M.Pharm awarded under his supervision. He is receipient of Shanti Bharti Award (1991), Prof. K.A.Thaker award (2007) and Prof. S. B. Sonwane memorial award (2013) for best paper published. He is Life member of APTI (Association of Pharmaceutical Teachers of India), IPA (Indian Pharmaceutical Association) and Institution of Chemists.

Nagendra Singh Chauhan obtained his M.Pharm, Ph.D from Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar in 2006 and 2011. He has around 14 years of research experience. He is presently working as Senior Scientific Officer Grade-II and Government Analyst at Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has professional Expertise in Natural Product Isolation and phytopharmacology. He has written more than 76 articles published in national and international journals, 35 book chapters and edited seven books. Recently edited book entitled “Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents” and “Natural Products in Vector Borne Disease Management: Published by Academic press. He has written more than 75 articles published in national and international journals, 32 book chapters and edited five books. He has citations of more than 2700 with h-index 42 and i10 index of 38 (Google scholar) and Scopus h-index 15; 669 citations. He is a member of various professional and academic bodies like Society of Pharmacognosy India, International Natural Product Sciences Taskforce (INPST) society, SILAE: SocietàItalo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), Institutional Human ethical committee, Association of Pharmaceutical Teachers of India (APTI) and Indian Pharmacy Graduates' Association.