Side Reactions in Peptide Synthesis

Yang Yi

ISBN 10: 0128010096 / ISBN 13: 9780128010099

Edité par Elsevier, 2015

A propos de cet article

pp. 320.

N° de réf. du vendeur 322553189

Détails bibliographiques

• Titre: Side Reactions in Peptide Synthesis
• Éditeur: Elsevier
• Date de parution: 2015
• Langue: anglais
• ISBN à 10 chiffres: 0128010096
• ISBN à 13 chiffres: 9780128010099
• Reliure: Couverture rigide
• État de l'article: New

A propos de ce titre

Synopsis

Side Reactions in Peptide Synthesis, based on the author's academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.

This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development.

While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay.

Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction.

À propos de l?auteur

Yi Yang began researching peptide synthesis in 2003, and obtained his doctoral degree at Bielefeld University, Germany in 2008. Dr. Yang worked for three years at Lonza AG, Visp, Switzerland as R&D and Process Peptide Chemist, participated in multi cGMP peptidyl API production at Lonza, which is regarded as one of the largest peptide contract manufacturing organization (CMO) in the world, serving pharmaceutical companies. He is currently the Senior Research Scientist of Chemical Development, Global Pharmaceutical R&D, Ferring Pharmaceuticals A/S, Copenhagen, Denmark. Dr. Yang's experience with a wide variety of peptide side reactions, from both practical and theoretical aspects, is ideal for this publication.