Used very good, all pages clean. STUDY GUIDE Quantity Available: 1. Category: Science & Technology; ISBN: 0471351962. ISBN/EAN: 9780471351962. Pictures of this item not already displayed here available upon request. Inventory No: ABE353947436.

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D�tails bibliographiques

Titre

Study Guide and Solutions Manual to Accompany Organic Chemistry, 7th

�diteur

John Wiley & Sons, Inc., Hoboken, NJ

Date de parution

1999

Langue

anglais

ISBN � 10 chiffres

0471351962

ISBN � 13 chiffres

9780471351962

Reliure

Softcover

�dition

7th Edition.

�tat de l'article

Very Good

Catalogues du vendeur

Science & Technology

A propos de ce titre

Synopsis

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!

Pr�sentation de l'�diteur

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100–year–old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It′s just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

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