Synthetic DNA Delivery Systems

. Ed(s): Luo, Dan; Saltzman, W. Mark

ISBN 10: 0306477017 / ISBN 13: 9780306477010

Edité par Springer Science+Business Media, 2003

DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. This is a comprehensive resource on DNA transfection. It discusses the use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers. Editor(s): Luo, Dan; Saltzman, W. Mark. Series: Biotechnology Intelligence Unit. Num Pages: 148 pages, biography. BIC Classification: PSB; TCB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 14. Weight in Grams: 870. . 2003. Hardback. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9780306477010

Synopsis :

DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function.

Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest.

Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.

Détails bibliographiques

Titre : Synthetic DNA Delivery Systems
Éditeur : Springer Science+Business Media
Date d'édition : 2003
Reliure : Couverture rigide
Etat : New