The TNF Superfamily : Methods and Protocols

Jagadeesh Bayry

ISBN 10: 1493906682 / ISBN 13: 9781493906680

Edité par Springer New York, Springer US, 2014

A propos de cet article

Druck auf Anfrage Neuware - Printed after ordering - Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.

N° de réf. du vendeur 9781493906680

Détails bibliographiques

• Titre: The TNF Superfamily : Methods and Protocols
• Éditeur: Springer New York, Springer US
• Date de parution: 2014
• Langue: anglais
• ISBN à 10 chiffres: 1493906682
• ISBN à 13 chiffres: 9781493906680
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 260 L x 183 H x 19 P (en millimètres) 260 millimètres de largeur par 183 millimètres de hauteur par 19 millimètres de profondeur
• Poids: 656 grammes

A propos de ce titre

Synopsis

Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.