Tumor Metabolome Targeting and Drug Development (Cancer Drug Discovery and Development)

Kanner, Steven

ISBN 10: 146149544X ISBN 13: 9781461495444
Edité par Humana, 2014
Neuf(s) Couverture rigide

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Editor(s): Kanner, Steven. Series: Cancer Drug Discovery and Development. Num Pages: 206 pages, 10 black & white illustrations, 12 colour illustrations, 1 black & white tables, biograph. BIC Classification: MBGR; MJCL; MMG; PSF. Category: (P) Professional & Vocational. Dimension: 240 x 163 x 16. Weight in Grams: 458. . 2014. 2014th Edition. hardcover. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9781461495444

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Synopsis :

Chapter 1: Tumor cell metabolic reprogramming and drug targeting (Steven B. Kanner)
Chapter 2: Cancer metabolism: a nexus of matter, energy and reactive oxygen species (Paul M. Bingham, Shawn D. Stuart, Zuzana Zachar) Chapter 3: Regulating mitochondrial respiration in cancer (Teresa L. Serafim and Paulo J. Oliveira)
Chapter 4: Regulation of cancer cell metabolism by hypoxia (Ashleigh Pulkoski-Gross, Nikki A. Evensen and Jian Cao)
Chapter 5: Glucose metabolism and the anti-oxidative defence system in cancer cells: Options for application of ROS-based anticancer drugs (Gernot Bruchelt, Rupert Handgretinger, Mirjam Weckenmann, Talia Hahn)
Chapter 6: Modulating autophagy and the "reverse Warburg effect" (Maria Vaccaro, Claudio D. Gonzalez, Silvia Alvarez and Alejandro Ropolo)
Chapter 7: Metabolic adaptation in reprogrammed cancer cells (Kevin Marks and Charles Kung)
Chapter 8: Targeting of PFKFB3 (Katarina Färnegårdh, Maria Shoshan, Lars Ährlund-Richter)

À propos de l?auteur: Dr. Steven B. Kanner is the Vice President of Discovery Biology at Astex Pharmaceuticals. He has been a pharmaceutical research leader with over 20 years of extensive experience in novel target identification and validation, assay development, both small molecule and antibody drug discovery, and expertise in oncology, immunology and inflammation. For more detail, please see the attached CV herewith.

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Titre : Tumor Metabolome Targeting and Drug ...
Éditeur : Humana
Date d'édition : 2014
Reliure : Couverture rigide
Etat : New

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