Xenotransplantation

Shuji Miyagawa

ISBN 10: 1789856639 / ISBN 13: 9781789856637

Edité par Intechopen Mär 2020, 2020

A propos de cet article

Neuware -Recently, remarkable progress has been made in the area of preclinical xenotransplantation experiments. Surprisingly, a heterotopic heart from the gene-editing pig continued to beat for almost 2.5 years, when implanted in the monkey abdomen, and a pig life-supporting kidney could also function for over 1.3 years in monkeys. Concerning islets, islets from gene-editing pigs could work for more than one year in monkeys. It is noteworthy that one group reported a survival of adult wild-type pig islets of over 600 days. On the other hand, the progress in these preclinical trials strongly affected not only the xenotransplantation study itself but regeneration studies to use pigs as a scaffold to foster human induced pluripotent stem cells.Books on Demand GmbH, Überseering 33, 22297 Hamburg 156 pp. Englisch.

N° de réf. du vendeur 9781789856637

Détails bibliographiques

• Titre: Xenotransplantation
• Éditeur: Intechopen Mär 2020
• Date de parution: 2020
• Langue: anglais
• ISBN à 10 chiffres: 1789856639
• ISBN à 13 chiffres: 9781789856637
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 266 L x 185 H x 16 P (en millimètres) 266 millimètres de largeur par 185 millimètres de hauteur par 16 millimètres de profondeur
• Poids: 558 grammes

A propos de ce titre

Synopsis

Recently, remarkable progress has been made in the area of preclinical xenotransplantation experiments. Surprisingly, a heterotopic heart from the gene-editing pig continued to beat for almost 2.5 years, when implanted in the monkey abdomen, and a pig life-supporting kidney could also function for over 1.3 years in monkeys. Concerning islets, islets from gene-editing pigs could work for more than one year in monkeys. It is noteworthy that one group reported a survival of adult wild-type pig islets of over 600 days. On the other hand, the progress in these preclinical trials strongly affected not only the xenotransplantation study itself but regeneration studies to use pigs as a scaffold to foster human induced pluripotent stem cells.