M F Smith studied medicine in the US (interrupted permanently by the Vietnam War), then geology in the UK before finishing a PhD in oceanography in Ireland. He moved to Switzerland, developed computer systems in the oil industry and started publishing technical papers. He settled in the UK in 1980 as an academic computer scientist and businessman. In the early 1990s, he became involved in medical computing as a professor of medicine and computer science at Keele. Eventually he moved to London, was appointed to a number of other professorial positions (UCL, LSE, Barts, City) worked in management consultancy and founded several technology companies. Now mostly retired to family life, he divides his time unequally between London and Central Europe.