Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
Langue : anglais
Edité par Springer, 2018
Série : Livre 5 sur 6 - Frontiers in Probability and the Statistical Sciences
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Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry | Susmita Datta (u. a.) | Taschenbuch | Frontiers in Probability and the Statistical Sciences | viii | Englisch | 2018 | Springer | EAN 9783319833774 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
N° de réf. du vendeur 114227201
- Titre
- Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
- Auteur
- Susmita Datta (u. a.)
- Éditeur
- Springer
- Année de publication
- 2018
- État de l'article
- Neu
- Reliure
- Taschenbuch
- Langue
- anglais
- ISBN à 10 chiffres
- 3319833774
- ISBN à 13 chiffres
- 9783319833774
- Poids de l'article
- 464 grammes
- Dimensions
- 235 x 155 x 17 mm
- Série
- Livre 5 sur 6: Frontiers in Probability and the Statistical Sciences
- Catalogues du vendeur
- Bücher
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies.
Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types--as opposed to the familiar data structures in more classical genomics--but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.
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À propos de l’auteur
Susmita Datta received her PhD in statistics from the University of Georgia. She is a tenured professor in the Department of Biostatistics at the University of Florida. Before joining the University of Florida she was a professor in the Department of Bioinformatics and Biostatistics and a distinguished university scholar at the University of Louisville. She is a Fellow of the American Association for the Advancement of Science (AAAS), American Statistical Association (ASA), and an elected member of the International Statistical Institute (ISI). Her research interests include bioinformatics, genomics, proteomics, clustering and classification techniques, infectious disease modeling, statistical issues in population biology, systems biology, survival analysis, and multi state models. She is past president of the Caucus for Women in Statistics, and she actively supports research and education for women in STEM fields.
Bart Mertens received his PhD in statistical sciences from University College London, Department of Statistical Sciences, on statistical analysis methods for spectrometry data. He is currently Associate Professor at the Department of Medical Statistics and Bioinformatics of the Leiden University Medical Centre, where he has been working in both research and consulting for statistical analysis methodology with mass spectrometry proteomic data for more than 10 years.
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