Oncogenes: An Introduction to the Concept of Cancer Genes

Burck, Kathy B.; Liu, Edison T.; Larrick, James W.; Lederberg, Joshua [Foreword]

ISBN 10: 0387964231 / ISBN 13: 9780387964232

Edité par Springer, 1989

A propos de cet article

***please read*** signed copy - no marks on text -my shelf location we-c-22*.

N° de réf. du vendeur 180525004

Détails bibliographiques

• Titre: Oncogenes: An Introduction to the Concept of Cancer Genes
• Éditeur: Springer
• Date de parution: 1989
• Langue: anglais
• ISBN à 10 chiffres: 0387964231
• ISBN à 13 chiffres: 9780387964232
• Reliure: Paperback
• Édition: 1st ed. 1988. Corr. 2nd printing.
• État de l'article: As New
• Signé: Signed by Author

A propos de ce titre

Synopsis

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat- form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.