This text presents specific applications to supramolecular and stereospecific synthesis. It discusses aspects of peptide and protein chemistry as well as highlighting how the amide linkage participates in the design of enzyme inhibitors, cyclic peptides and antibacterial agents. Editor(s): Breneman, Curt M.; Liebman, Joel F.; Greenberg, Arthur. Num Pages: 672 pages, Ill. BIC Classification: PNNP; PNR; TGM. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 239 x 165 x 38. Weight in Grams: 1070. . 2000. 1st Edition. Hardcover. . . . .

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D�tails bibliographiques

Titre: The Amide Linkage
�diteur: John Wiley and Sons Ltd
Date de parution: 2000
Langue: anglais
ISBN � 10 chiffres: 0471358932
ISBN � 13 chiffres: 9780471358930
Reliure: Couverture rigide
�dition: Edition originale
�tat de l'article: New

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Synopsis

Die Peptidbindung ist eine der wichtigsten und h�ufigsten chemischen Bindungen in der Natur. Sie bestimmt die Eigenschaften von organischen Molek�len und Makromolek�len, Peptiden und Proteinen. Dieser Band bietet eine F�lle von Details zur Struktur, Bindung und Energetik, Elektronendichteverteilung, Amidrotation, Stereochemie, Spektroskopie und Thermochemie. Spezielle Aspekte wie die stereospezifische Synthese kommen ebenso zur Sprache wie Einzelheiten der Funktion der Peptidbindung in Enzyminhibitoren, cyclischen Peptiden und bakteriziden Wirkstoffen. (02/00)

� propos de l?auteur

ARTHUR GREENBERG, PhD, is Professor in the Department of Chemistry at the University of New Hampshire.

CURT M. BRENEMAN, PhD, is Professor in the Department of Chemistry at Rensselaer Polytechnic Institute.

JOEL F. LIEBMAN, PhD, is Professor in the Department of Chemistry and Biochemistry at the University of Maryland, Baltimore County.

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