The Effect of Adrenalectomy on Radiation Induced Mortality of the Mouse; Project NM 006 012.04.30 (Formerly NM 007 039)

Edité par National Naval Medical Center, Naval Medical Research Institute, Bethesda, MD, 1950

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[2], 4, [4] pages. Footnotes. Tables. Figure. References. Stamp of previous owner and some notations/marks on title page. Ink mark and correction made on page 1. Cover has some wear and soiling. It is of interest that the shorter survival time of adrenalectomized animals suggest an increased radiosensivity. The failure of adrenalectomy to increase the mortality of ionizing radiation in previous work was inconsistent with past observations on the effect of adrenalectory on stresses in general. Therefore the authors felt it desirable to repeat the previous work, determining the effect of adrenalectomy on the entire lethal dose curve. The adrenal insufficient mouse was more sensitive to irradiation than the normal mouse. The survival time in adrenalectomized mice was shortened. The cause of death in the adrenalectomized irradiated mouse was apparently due to mechanisms other than infection and hemorrhage. The author became a Brookhaven National Laboratory Senior Scientist emeritus and was a former Medical Department Chairman. While in the U.S. Navy, 1942- 54, he collaborated on developing techniques for platelet and granulocyte transfusions, both crucial for blood clotting, fighting infections and also for treating acute leukemia. In 1946, he became Head Hematologist at the Naval Medical Research Institute. In March 1954, Gene was sent to the Marshall Islands to study and treat its inhabitants and the American servicemen who were accidentally exposed to fallout from a nuclear test. In the wake of the Castle Bravo detonation, a new research section was added to the Castle Bravo Weapons Effects research section. Program 4, "Biomedical effects," was to include Project 4.1, titled "Study of Response of Human Beings exposed to Significant Beta and Gamma Radiation due to Fall-out from High-Yield Weapons." Eugene P. Cronkite of the National Naval Medical Center was designated as Project Officer.…

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Détails bibliographiques

Titre
The Effect of Adrenalectomy on Radiation Induced Mortality of the Mouse; Project NM 006 012.04.30 (Formerly NM 007 039)
Auteur
Cronkite, E. P., and Chapman, W. H.
Éditeur
National Naval Medical Center, Naval Medical Research Institute, Bethesda, MD
Année de publication
1950
État de l'article
Good
Reliure
Wraps
Édition
Presumed First Edition, First printing.

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