IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity

Valérie Quesniaux

ISBN 10: 3034805217 / ISBN 13: 9783034805216

Edité par Springer Basel, Springer Basel Dez 2012, 2012

A propos de cet article

Neuware -The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition ¿Th17 Cells: Role in Inflammation and Autoimmune Disease¿ in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Englisch.

N° de réf. du vendeur 9783034805216

Détails bibliographiques

• Titre: IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
• Éditeur: Springer Basel, Springer Basel Dez 2012
• Date de parution: 2012
• Langue: anglais
• ISBN à 10 chiffres: 3034805217
• ISBN à 13 chiffres: 9783034805216
• Reliure: Buch
• Édition: Edition originale
• État de l'article: Neu

A propos de ce titre

Synopsis

In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.