Lipoic Acid: Energy Production, Antioxidant Activity and Health Effects (Oxidative Stress And Disease, 24)

Langue : anglais

Edité par CRC Press, 2008

1420045377 / 9781420045376

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532 pp., diagrams, bibliography, index. owner's name on FFEP. The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants. Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest as a coenzyme in mitochondrial energy metabolism and as an antioxidant and cell redox modulator. Mounting data regarding its potential health benefits demands an authoritative, single-source reference to codify current knowledge and guide future research. A state-of-the-science compilation, Lipoic Acid follows the history of this potent coenzyme and the latest discoveries regarding the chemistry, biological action, and significance in energy production, antioxidant activity, and health. The book is divided into three sections: · Section I: Discovery and Molecular Structure reviews the early studies leading to the discovery of alpha-lipoic acid and explains the molecular structure, biosynthesis, and the characterization of lipoic acid and its chemical derivatives. · Section II: Metabolic Aspects describes in detail the human pharmacokinetics of alpha-lipoic acid including the lipoic acid-derived dehydrogenase complexes and their roles in energy metabolism. It also explains antioxidant activity and redox modulation and how lipoic acid induces Phase II detoxification enzymes through activation of Nrf2-dependent gene expression. · Section III Clinical Aspects discusses enzyme deficiency disorders and the effects of lipoic acid on insulin. It defines lipoic acid influence on signaling pathways and AMP-activated kinase, and considers the therapeutic implications for treatment of metabolic syndromes and the improvement of mitochondrial function by lipoic acid supplementation.

N° de réf. du vendeur 1420045377AMES080220

Titre
Lipoic Acid: Energy Production, Antioxidant Activity and Health Effects (Oxidative Stress And Disease, 24)
Auteur
Patel, Mulchand S (Editor), and Packer, Lester (Editor)
Éditeur
CRC Press
Année de publication
2008
État de l'article
Very Good
Reliure
Hardcover
Langue
anglais
ISBN à 10 chiffres
1420045377
ISBN à 13 chiffres
9781420045376
Édition
1st Edition

Masalai Press

Oakland, CA, Etats-Unis

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 28 décembre 2011

Frais d'expédition à l'intérieur de ce pays : Etats-Unis

Article5 à 14 jours ouvrés2 à 4 jours ouvrés
Premier articleEUR 5,20EUR 11,26
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Masalai Press has been selling books on the internet since 2000, and has been involved in book selling since 1985. Customer service and accurate descriptions are a priority. Masalai Press specializes in books about the Pacific Islands, especially Papua New Guinea. Masalai Press is the regional representative of the University of Papua New Guinea Press, and has been co-publishing with the UPNG Press since 2008.

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Papua New Guinea, Pacific Islands, Asia, Linguistics, Foreign Language Dictionaries, Sciences

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Masalai Press

CA, Etats-Unis