Principles of Nucleic Acid Structure

Neidle, Stephen

ISBN 10: 0123695074 / ISBN 13: 9780123695079

Edité par Elsevier Science & Technology, 2007

A propos de cet article

Ships from the UK. Former library book; may include library markings. Used book that is in excellent condition. May show signs of wear or have minor defects.

N° de réf. du vendeur 52086817-20

Détails bibliographiques

• Titre: Principles of Nucleic Acid Structure
• Éditeur: Elsevier Science & Technology
• Date de parution: 2007
• Langue: anglais
• ISBN à 10 chiffres: 0123695074
• ISBN à 13 chiffres: 9780123695079
• Reliure: Couverture souple
• Édition: 1st Edition.
• État de l'article: Very Good
• Poids: 1,444 livre

A propos de ce titre

Synopsis

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software.

À propos de l?auteur

Stephen Neidle is an Emeritus Professor of Chemical Biology at University College London, where he has also been the Director of Research in the School of Pharmacy. He has published over 500 primary papers and reviews and is a principal inventor on 14 patent filings. He has also written and edited several books on nucleic acids and anti-cancer drugs.