G Protein Methods and Protocols: Role of G Proteins in Psychiatric and Neurological Disorders

Mishra, Ram K. (editor)

ISBN 10: 0896034909 / ISBN 13: 9780896034907

Edité par Humana Pr Inc, Secaucus, New Jersey, U.S.A., 1997

a very good hardcover; an ex-library copy with usual markings; internally pages bright and clean; ---------- SATISFACTION GUARANTEED --------- FAST, COURTEOUS SERVICE ------ Size: 6 x 9". N° de réf. du vendeur A80609

Synopsis :

The G proteins are a family of structurally homologous, plasma membrane-associated guanine-nucleotide-binding proteins. These proteins play an integral role in the tra- duction of extracellular signals through second messenger systems. As such, G proteins affect a wide variety of intra cellular biochemical reactions by regulating the concent- tion of second messengers in cells. G proteins are heterotrimeric, consisting of a, p, and y polypeptide chains, with G protein specificity largely det- mined by the a-subunit, Molecular cloning of G protein s- units has revealed 23 distinct a-subunits, encoded by 17 different genes. Based on functional measures, G proteins are generally classified into three major categories: the G, family, which is stimulatory for adenylyl cyclase; the G, f- ily, which is inhibitory for adenylyl cyclase; and the G, f- ily, which stimulates phospholipases (Birnbaumer and Birnbaumer, 1995). Alternatively, on the basis of sequence homology, G proteins can be subdivided into four cate- ries: G, G, G, and G12.

Détails bibliographiques

Titre : G Protein Methods and Protocols: Role of G ...
Éditeur : Humana Pr Inc, Secaucus, New Jersey, U.S.A.
Date d'édition : 1997
Reliure : Hard Cover
Etat : Very Good
Etat de la jaquette : No Dustjacket
Edition : First Edition.
Type de livre : Ex-Library