Two Hydrogen-Bonded Spiral Configurations of the Polypeptide Chain in The Journal of the American Chemical Society, Vol. LXXII [72], September-December 1950, 5349

Edité par American Chemical Society, Easton, 1950

  • Éd. originale
  • Occasion
Afficher toutes les informations

Vendeur : Atticus Rare Books, West Branch, IA, Etats-UnisAtticus Rare Books

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 23 août 2001

Etat: Occasion

EUR 1 152,27

EUR 8,50 expédition 
Expédition nationale : Etats-Unis

Quantité disponible : 1 disponible

Ajouter au panier
Retours gratuits sous 30 jours

A propos de cet article

FIRST EDITION OF LINUS PAULING AND ROBERT COREY'S FIRST ANNOUNCEMENT OF THEIR SEMINAL MOLECULAR BIOLOGY FINDINGS REGARDING THE THEORETICAL ALPHA AND GAMMA HELIXES, TWO CONFIGURATIONS OF THE ARRANGEMENT OF ATOMS IN PROTEINS. The authors "must have realized the bombshell they had dropped on the scientific world. Knowledge of the inner workings of proteins -- molecules often referred to as the building blocks of life -- would be the key to understanding biology at the molecular level" (Brownlee in PNAS Website). A full decade before x-ray crystallography first revealed the structures of proteins, Pauling and Corey deduced their main structural features: the alpha and the gamma helix. Their work had the same significance for proteins as the Watson and Crick papers, published two years later, had for the structure of DNA. In the short letter that published in this volume, the two scientists clearly state "that they had come up with two spiral models; they mention their hydrogen bonding scheme and assert that there was evidence that the proposed structures were present in a variety of proteins. They hinted at a molecular model for silk. They said nothing about the discrepancy between their models and the x-ray data. They ended with the promise that 'a detailed account of this work will be published soon'" (Special Collections and Archive Research, Oregon State). "Pauling and Corey's research, now over a half-century old, guides today's biotechnology revolution and the search for hundreds of disease cures -- drugs that may someday conquer Alzheimer's disease, cystic fibrosis, Mad Cow disease and many forms of cancer" (Brownlee). Linus Paulingwon the 1954 Nobel Prize in Chemistry "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances' (Nobel Prize Committee). CONDITION & DETAILS: Easton: American Chemical Society. Full volume. Quarto (10.25 x 7.5 inches; 256 x 188mm). Bound in maroon cloth with decorative paper boards. Gilt-lettered, green morocco spine label. Minor rubbing and scuffing at the edges. Tiny spot on spine label. Tightly and very solidly bound. Bright and clean throughout. Very good condition.…

N° de réf. du vendeur 357

Détails bibliographiques

Titre
Two Hydrogen-Bonded Spiral Configurations of the Polypeptide Chain in The Journal of the American Chemical Society, Vol. LXXII [72], September-December 1950, 5349
Auteur
Pauling, Linus; Corey, Robert B.
Éditeur
American Chemical Society, Easton
Année de publication
1950
Édition
1st Edition.
Catalogues du vendeur
Atomic & Particle Physics, & Quantum Theory, DNA, X-ray Crystallography

Atticus Rare Books

West Branch, IA, Etats-Unis

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 23 août 2001

Frais d'expédition à l'intérieur de ce pays : Etats-Unis

Article3 à 6 jours ouvrés2 à 4 jours ouvrés
Premier articleEUR 8,50EUR 9,49
Les délais de livraison sont fixés par les vendeurs et varient en fonction du transporteur et du lieu. Les commandes transitant par les douanes peuvent être retardées et les acheteurs sont responsables de tous les droits ou frais associés. Les vendeurs peuvent vous contacter au sujet de frais supplémentaires afin de couvrir toute augmentation des coûts d'expédition de vos articles.

Modes de paiement

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay
  • Chèque
  • Mandat
  • Paypal
  • Virement bancaire

Spécialité

Antiquarian & 20th Century Science, Physics, Astronomy, Mathematics, & Medicine

Profil professionnel du vendeur

Atticus Rare Books

IA, Etats-Unis