What's Wrong With My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice (Second Edition)

Crawley, Jacqueline N.

14 évaluations par Goodreads

Langue : anglais

Edité par John Wiley & Sons, Inc, Hoboken, 2007

0471471925 / 9780471471929

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First Edition. Hardcover. 10 1/4" X 7 1/4". xvi, 523pp. First edition, with full number line indicating first printing. Bound in glossy pictorial paper over boards. Mild rubbing and shelf wear to covers, corners, and edges of binding. Pages are clean and unmarked. Binding is firm and sound. ABOUT THIS BOOK: Learn how to conduct behavioral tests to phenotype mutant mice Dr. Jacqueline N. Crawley, author of the first and second editions of What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field hundreds of calls and e-mails from molecular geneticists who ask just that: How do I run behavioral assays to find out what's wrong with my mouse? This book answers that question and many more, including what tests are available to discover an aberrant behavioral phenotype? Turn to What's Wrong With My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the second edition up to date with the latest science. In addition, the second edition includes two new chapters: Neurodevelopment and Neurodegeneration discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis. Putting It All Together recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, The Next Generation, examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor Web sites, suggestions for expert behavioral neuroscientist collaborators, and an extensive list of references, make this book a valuable and practical resource for students and researchers.(Publisher).

N° de réf. du vendeur 13235

Titre
What's Wrong With My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice (Second Edition)
Auteur
Crawley, Jacqueline N.
Éditeur
John Wiley & Sons, Inc, Hoboken
Année de publication
2007
État de l'article
Very good
Reliure
Hardcover
Langue
anglais
ISBN à 10 chiffres
0471471925
ISBN à 13 chiffres
9780471471929
Édition
First Edition.
Catalogues du vendeur
Science & Nature

Underground Books, ABAA

Indianapolis, IN, Etats-Unis

Vendeur avec une évaluation de 5 étoiles

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Underground Books, ABAA is an online rare and antiquarian bookshop, founded in 2011 as a brick and mortar general bookstore of the same name in downtown Carrollton, Georgia, which is now operated by out former store manager as The Underground Bookshop. Co-owners Josh Niesse and Megan Bell met in 2011, just 10 days or so after Josh opened the doors of Underground Books, literally underground, several steps below street level in a 100-year-old basement in our historic downtown. Megan, an English student at the University of West Georgia, walked in, fell down the rabbit hole, and never left! Reader, we married in May of 2014, under the book arch that now resides at the bookshop. We are both proud alumni of the Colorado Antiquarian Book Seminar (CABS), and Megan additionally of Rare Book School at the University of Virginia and of the ABAA Women’s Initiative Mentorship Program. Like many booksellers with open brick-and-mortar stores, we are passionate generalists, but our specialties are in decorative publisher's cloth bindings; fairy tales, folklore, and mythology; popular science and natural history; the occult; and fine press books.

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academic out of print, modern firsts, signed modern firsts, decorative publisher's cloth bindings, fairy tales, folklore, and mythology, popular science and natural history, the occult, fine press books

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