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Synopsis
Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the "junk" DNA since it does not code for any "useful" protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book, the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements.
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Genomic Elements in Health, Disease and Evolution: Junk DNA
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Springer, 2015
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ISBN 13 : 9781493930692
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Genomic Elements in Health, Disease and Evolution: Junk DNA (eng)
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Genomic Elements in Health, Disease and Evolution
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Springer New York Okt 2015, 2015
ISBN 10 : 1493930699
ISBN 13 : 9781493930692
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the 'junk' DNA since it does not code for any 'useful' protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book,the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements. 328 pp. Englisch. N° de réf. du vendeur 9781493930692
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Genomic Elements in Health, Disease and Evolution
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ISBN 10 : 1493930699
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes information and novel functions about all the known genomic elements in a single publication Discusses the physiologic function of these elements their role in disease and evolution This book is dedicated exclusively to non-coding . N° de réf. du vendeur 32581638
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Genomic Elements in Health, Disease and Evolution: Junk DNA
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Genomic Elements in Health, Disease and Evolution
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Springer New York, Springer US Okt 2015, 2015
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ISBN 13 : 9781493930692
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Buch. Etat : Neu. Neuware -Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the ¿junk¿ DNA since it does not code for any ¿useful¿ protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book, the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch. N° de réf. du vendeur 9781493930692
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Genomic Elements in Health, Disease and Evolution : Junk DNA
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ISBN 13 : 9781493930692
Ancien ou d'occasion
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Genomic Elements in Health, Disease and Evolution: Junk DNA
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Genomic Elements in Health, Disease and Evolution : Junk DNA
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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the 'junk' DNA since it does not code for any 'useful' protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book,the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements. N° de réf. du vendeur 9781493930692
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Genomic Elements in Health, Disease and Evolution: Junk DNA
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