DNA Methyltransferases - Role and Function - Couverture souple

Couverture souple

ISBN 10 : 3319828703 ISBN 13 : 9783319828701

Editeur : Springer International Publishing AG, 2018

Synopsis

DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-havefor advanced researchers in the field of DNA methylation and epigenetics.

A propos du livre

À propos de l'auteur

Albert Jeltsch is Pofessor for Biochemistry at the University of Stuttgart, Germany.

Renata Jurkowska is Group Leader in Biochemistry and Molecular Epigenetics at the University of Stuttgart, Germany.

Détails de l'édition

• Éditeur: Springer International Publishing AG
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 3319828703
• ISBN 13: 9783319828701
• Reliure: Broché
• Nombre de pages: 543
• Éditeur: Jeltsch Albert, Jurkowska Renata Z.
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3,69115 Heidelberg, Germany; Heidelberg; 69115; Allemagne