Dna methyltransferases role function (20 résultats)

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Taschenbuch. Etat : Neu. DNA Methyltransferases - Role and Function | Albert Jeltsch (u. a.) | Taschenbuch | viii | Englisch | 2018 | Springer | EAN 9783319828701 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-havefor advanced researchers in the field of DNAmethylation and epigenetics.…

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.Like the previous edition, this 2ndedition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2ndedition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.…

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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.Like the previous edition, this 2ndedition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2ndedition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.…

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Langue : anglais
Edité par Springer Jul 2018, 2018
Série : Livre 271 sur 544 - Advances in Experimental Medicine and Biology
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-havefor advanced researchers in the field of DNAmethylation and epigenetics. 544 pp. Englisch.…

Langue : anglais
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.Like the previous edition, this 2ndedition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2ndedition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field. 572 pp. Englisch.…

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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.Like the previous edition, this 2ndedition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2ndedition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field. 572 pp. Englisch.…

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation - from past achievements to future challenges.- Chapter 2.Bacterial DNA Methylation and Methylomes.- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.- Chapter 4. Enzymology of Mammalian DNA Methyltransferases.- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase.- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases.- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics.- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark.- Chapter 9. Pathways of DNA Demethylation.- Chapter 10. Structure and Function of TET Enzymes.- Chapter 11.Proteins That Read DNA Methylation.- Chapter 12. Recent advances on DNA base flipping - a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer.- Chapter 14. DNMTs and DNA damage.- Chapter 15. Role of DNMTs in brain.- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation.- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach .- Chapter 19. DNA Labeling Using DNA Methyltransferases.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 572 pp. Englisch. …

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Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation - from past achievements to future challenges.- Chapter 2.Bacterial DNA Methylation and Methylomes.- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.- Chapter 4. Enzymology of Mammalian DNA Methyltransferases.- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase.- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases.- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics.- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark.- Chapter 9. Pathways of DNA Demethylation.- Chapter 10. Structure and Function of TET Enzymes.- Chapter 11.Proteins That Read DNA Methylation.- Chapter 12. Recent advances on DNA base flipping - a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer.- Chapter 14. DNMTs and DNA damage.- Chapter 15. Role of DNMTs in brain.- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation.- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach .- Chapter 19. DNA Labeling Using DNA Methyltransferases.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 572 pp. Englisch.…