Protein-Protein Interactions in Hetero-dimer Complexes: Protein Hetero-dimer Interfaces - Couverture souple

Sowmya, Gopichandran; Pandjassarame, .; Kangueane, .

 
9783844385465: Protein-Protein Interactions in Hetero-dimer Complexes: Protein Hetero-dimer Interfaces

Synopsis

Protein heterodimer (two dissimilar proteins) complexes are often involved in catalysis, regulation, assembly, immunity and inhibition. This involves the formation of stable interfaces between the interacting partners. The molecular principle of protein-protein binding is not fully known. Analysis of protein structures determined by X-ray crystallography in its protein dimer state provides valuable insights to the understanding of protein-protein interactions. This book documents the current opinion for the driving force in protein-protein binding using the analysis of known protein heterodimer structures. The book also provides 50 simple exercises for the understanding of protein-protein interactions.

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Présentation de l'éditeur

Protein heterodimer (two dissimilar proteins) complexes are often involved in catalysis, regulation, assembly, immunity and inhibition. This involves the formation of stable interfaces between the interacting partners. The molecular principle of protein-protein binding is not fully known. Analysis of protein structures determined by X-ray crystallography in its protein dimer state provides valuable insights to the understanding of protein-protein interactions. This book documents the current opinion for the driving force in protein-protein binding using the analysis of known protein heterodimer structures. The book also provides 50 simple exercises for the understanding of protein-protein interactions.

Biographie de l'auteur

Gopichandran Sowmya graduated with B.Tech (Bioinformatics) from VIT University, India. Graduate Student in MS (Biotechnology) at AIMST University, Malaysia. Bioinformatics Consultant at Biomedical Informatics, India

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