Titre: Microfluidic Technologies for Single-Cell Analysis: Creating uniform cellular microenvironments for fast timescale measurements
�diteur: VDM Verlag
Date de parution: 2009
Langue: anglais
ISBN � 10 chiffres: 3639139518
ISBN � 13 chiffres: 9783639139518
Reliure: Couverture souple
�tat de l'article: New

A propos de ce titre

Synopsis

Analysis of single cells allows a complete understanding of the heterogeneity that is present in cell behavior and function. Current single-cell analysis methods provide high-throughput information about labeled biomolecules within cells, but often cannot follow the dynamic processes occurring in signaling pathways. New microfluidic methods have separately allowed assays of fast timescale responses or creation of uniform environments to study cell behavior in a more quantitative manner. This book focuses on microfluidic hydrodynamic trapping techniques that aid in both fast timescale measurements and uniform environmental control in a single platform. Example applications for fast timescale analysis of pore-forming toxin insertion into membranes and assays of single-cell enzyme content will be presented. The book would be of interest to analytical chemists, engineers, and biologists developing platforms to study single-cell behavior. Also, biologists looking for tools to study cells of interest with statistical accuracy would find the book most helpful.

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