Protective Groups in Organic Synthesis

Greene, Theodora W., Wuts, Peter G.

ISBN 10: 0471623016 / ISBN 13: 9780471623014

Edité par Wiley & Sons, Incorporated, John, 1991

A propos de cet article

Former library book; may include library markings. Used book that is in clean, average condition without any missing pages.

N° de réf. du vendeur GRP37819278

Détails bibliographiques

• Titre: Protective Groups in Organic Synthesis
• Éditeur: Wiley & Sons, Incorporated, John
• Date de parution: 1991
• Langue: anglais
• ISBN à 10 chiffres: 0471623016
• ISBN à 13 chiffres: 9780471623014
• Reliure: Couverture rigide
• Édition: 2ème Édition
• État de l'article: Good

A propos de ce titre

Synopsis

A frequent requirement in organic synthesis is the protection of one or more of the major functional groups - the hydroxyl, amino, carboxyl, carbonyl and sulfhydryl groups. For these major functional groups, this book provides concise, comprehensive coverage of the most useful protective groups. For each functional group, a short section discusses the chemistry of the classes of protective groups that are available. The chemistry of the individual protective groups in the class is then described using structures, equations and references.

Quatrième de couverture

The Most Comprehensive Guide to Protective Groups in Organic Synthesis Currently Available For more than twenty–five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence. The Fourth Edition includes significant developments in protective group chemistry since 1998. In addition to incorporating new protective groups now available to the synthetic organic chemist, such as the uniquely removable 2–methoxybenzenesulfonyl group for the protection of amines, the book also covers new techniques for the formation and cleavage of existing protective groups, providing the most relevant and useful examples to illustrate each methodology. The content is organized around the functional group to be protected (ethers, acids, carbonyl groups, amines, amides, phenols, etc.), and ranges from the simplest to the most complex highly specialized protective groups. New features of the Fourth Edition include: The addition of numerous new protective groups, such as the fluorous family New methods for the cleavage and introduction of many of the classic protective groups highlighting selectivity issues when reported in the literature Expanded coverage of the unexpected side reactions that occur with protective groups A new chart covering the selective deprotection of silyl ethers 3,100 new references from the professional literature, complete through the end of 2005