Synthesis of Few Potential Non-Steroidal Anti-Inflammatory Agents

Sarma, Prasanta Kumar/ Debnath, Biplab/ Mandal, Sudip Kumar

ISBN 10: 3659929026 / ISBN 13: 9783659929021

Edité par LAP LAMBERT Academic Publishing, 2016

64 pages. 8.66x5.91x0.15 inches. In Stock. N° de réf. du vendeur 3659929026

Synopsis :

Non-steroidal anti-inflammatory drugs are one of the commonly prescribed groups of drugs worldwide and are highly effective as analgesic, antipyretic and anti-inflammatory agents. However, their use is also associated with adverse events such as gastro duodenal ulceration and gastro intestinal bleeding. There is always a great need to develop COX-2 specific inhibitors to avoid the side effects. The present report contains a brief introduction to inflammation, biosynthesis of prostaglandins with emphasis on the enzymes COX-1 and COX-2. The main focus is on the literature survey of indan derivatives and experimental work carried out in the laboratory in an attempt to develop newer and less ulcerogenic NSAIDs.

Présentation de l'éditeur: Non-steroidal anti-inflammatory drugs are one of the commonly prescribed groups of drugs worldwide and are highly effective as analgesic, antipyretic and anti-inflammatory agents. However, their use is also associated with adverse events such as gastro duodenal ulceration and gastro intestinal bleeding. There is always a great need to develop COX-2 specific inhibitors to avoid the side effects. The present report contains a brief introduction to inflammation, biosynthesis of prostaglandins with emphasis on the enzymes COX-1 and COX-2. The main focus is on the literature survey of indan derivatives and experimental work carried out in the laboratory in an attempt to develop newer and less ulcerogenic NSAIDs.

Détails bibliographiques

Titre : Synthesis of Few Potential Non-Steroidal ...
Éditeur : LAP LAMBERT Academic Publishing
Date d'édition : 2016
Reliure : Paperback
Etat : Brand New