Marta halasa (36 résultats)

Etat : new.

Hardcover. Etat : new. Hardcover. This volume covers recent developments on the role, composition, and functional significance of intercellular and interorganellar transfer. It highlights the involvement of intercellular and interorganellar transfer in cell and developmental biology, differentiation, pathogen dissemination, shaping the genetic makeup of organisms, and the development of various diseases.Animals and plants evolved different communication mechanisms and transfer of molecules and organelles between cells and between organelles within the individual cells. Tunneling nanotubes (TNTs) in animals, discovered as recently as 2004, and their functional equivalent in plants, plasmodesmata, discovered over 100 years ago, are the membranous bridges that mediate the transfer of organelles, membrane patches, vesicles, DNA/RNA, and different molecules between cells. In addition, there are other means of transfer and communication between the cells, such as cytonemes, airinames, extracellular vesicles (exosomes), and others. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. The exchange of intact membrane patches (trogocytosis) between cells of the immune system may modify the immune response. Additionally, the transfer of genetic information between nucleus and organelles and cells of different species can shape the species and evolutionary outcome. Viral and bacterial pathogens can hijack the inter-cellular transfer routes to spread more efficiently. Cell-to-cell transfer of animal and plant pathogens can also occur by the virological synapse (VS). These specialized pathogen-induced structures share similarities and differences with neurological and immunological synapses. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. …

Taschenbuch. Etat : Neu. Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease | Marta Halasa (u. a.) | Taschenbuch | Results and Problems in Cell Differentiation | ix | Englisch | 2026 | Springer | EAN 9783031914614 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Etat : new.

Taschenbuch. Etat : Neu. Monocytes and Macrophages in Development, Regeneration, and Disease | Malgorzata Kloc (u. a.) | Taschenbuch | Results and Problems in Cell Differentiation | viii | Englisch | 2025 | Springer | EAN 9783031659461 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Hardcover. Etat : Brand New. 586 pages. 9.25x6.10x9.49 inches. In Stock.

Taschenbuch. Etat : Neu. Intercellular and Interorganellar Transfer and Communication in Biology and Medicine | Malgorzata Kloc (u. a.) | Taschenbuch | Results and Problems in Cell Differentiation | ix | Englisch | 2025 | Springer | EAN 9783031620386 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.The book is divided in four parts:Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organization and explores the functions of the proteins involved.Part II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation. It examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.Part III examines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.Part IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.The book is a valuable resource for scientists, clinicians and academic teachers alike.…

Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.The book is divided in four parts:Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organization and explores the functions of the proteins involved.Part II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation. It examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.Part III examines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.Part IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.The book is a valuable resource for scientists, clinicians and academic teachers alike.…

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.…

Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.…

Hardcover. Etat : Brand New. 586 pages. 9.25x6.10x9.49 inches. In Stock.

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume covers recent developments on the role, composition, and functional significance of intercellular and interorganellar transfer. It highlights the involvement of intercellular and interorganellar transfer in cell and developmental biology, differentiation, pathogen dissemination, shaping the genetic makeup of organisms, and the development of various diseases.Animals and plants evolved different communication mechanisms and transfer of molecules and organelles between cells and between organelles within the individual cells. Tunneling nanotubes (TNTs) in animals, discovered as recently as 2004, and their functional equivalent in plants, plasmodesmata, discovered over 100 years ago, are the membranous bridges that mediate the transfer of organelles, membrane patches, vesicles, DNA/RNA, and different molecules between cells. In addition, there are other means of transfer and communication between the cells, such as cytonemes, airinames, extracellular vesicles (exosomes), and others. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. The exchange of intact membrane patches (trogocytosis) between cells of the immune system may modify the immune response. Additionally, the transfer of genetic information between nucleus and organelles and cells of different species can shape the species and evolutionary outcome. Viral and bacterial pathogens can hijack the inter-cellular transfer routes to spread more efficiently. Cell-to-cell transfer of animal and plant pathogens can also occur by the virological synapse (VS). These specialized pathogen-induced structures share similarities and differences with neurological and immunological synapses.…

Hardcover. Etat : new. Hardcover. This volume covers recent developments on the role, composition, and functional significance of intercellular and interorganellar transfer. It highlights the involvement of intercellular and interorganellar transfer in cell and developmental biology, differentiation, pathogen dissemination, shaping the genetic makeup of organisms, and the development of various diseases.Animals and plants evolved different communication mechanisms and transfer of molecules and organelles between cells and between organelles within the individual cells. Tunneling nanotubes (TNTs) in animals, discovered as recently as 2004, and their functional equivalent in plants, plasmodesmata, discovered over 100 years ago, are the membranous bridges that mediate the transfer of organelles, membrane patches, vesicles, DNA/RNA, and different molecules between cells. In addition, there are other means of transfer and communication between the cells, such as cytonemes, airinames, extracellular vesicles (exosomes), and others. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. The exchange of intact membrane patches (trogocytosis) between cells of the immune system may modify the immune response. Additionally, the transfer of genetic information between nucleus and organelles and cells of different species can shape the species and evolutionary outcome. Viral and bacterial pathogens can hijack the inter-cellular transfer routes to spread more efficiently. Cell-to-cell transfer of animal and plant pathogens can also occur by the virological synapse (VS). These specialized pathogen-induced structures share similarities and differences with neurological and immunological synapses. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. …

Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume covers recent developments on the role, composition, and functional significance of intercellular and interorganellar transfer. It highlights the involvement of intercellular and interorganellar transfer in cell and developmental biology, differentiation, pathogen dissemination, shaping the genetic makeup of organisms, and the development of various diseases.Animals and plants evolved different communication mechanisms and transfer of molecules and organelles between cells and between organelles within the individual cells. Tunneling nanotubes (TNTs) in animals, discovered as recently as 2004, and their functional equivalent in plants, plasmodesmata, discovered over 100 years ago, are the membranous bridges that mediate the transfer of organelles, membrane patches, vesicles, DNA/RNA, and different molecules between cells. In addition, there are other means of transfer and communication between the cells, such as cytonemes, airinames, extracellular vesicles (exosomes), and others. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. The exchange of intact membrane patches (trogocytosis) between cells of the immune system may modify the immune response. Additionally, the transfer of genetic information between nucleus and organelles and cells of different species can shape the species and evolutionary outcome. Viral and bacterial pathogens can hijack the inter-cellular transfer routes to spread more efficiently. Cell-to-cell transfer of animal and plant pathogens can also occur by the virological synapse (VS). These specialized pathogen-induced structures share similarities and differences with neurological and immunological synapses.…

Etat : new. Questo è un articolo print on demand.

Etat : new. Questo è un articolo print on demand.

Etat : new. Questo è un articolo print on demand.

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 444 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.The book is divided in four parts:Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organization and explores the functions of the proteins involved.Part II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation. It examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.Part III examines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.Part IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.The book is a valuable resource for scientists, clinicians and academic teachers alike. 444 pp. Englisch.…

Etat : new. Questo è un articolo print on demand.

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt.

Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great succe.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages. 396 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages. 396 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies. The book is divided in four parts:- Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organization and explores the functions of the proteins involved.- Part II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation. It examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.- Part III examines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.- Part IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.The book is a valuable resource for scientists, clinicians and academic teachers alike.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, Heidelberg 444 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 444 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 396 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs.Following the great success of Volume 62: 'Macrophages - Origin, Functions and Biointervention' published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system.The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV.For ease of reference, the volume is divided into three sections:Part I Nonimmunologic and immunologic functions of monocytes/macrophagesPart II Tissue/organ specific functions of macrophagesPart III Macrophage functions and dysfunction in diseasesThis book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 396 pp. Englisch.…