Faller bernard (4 résultats)
Edité par E.M. Press
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Vendeur : Wonder Book, Frederick, MD, Etats-UnisWonder Book
Contacter le vendeurVendeur avec une évaluation de 5 étoilesEtat: Occasion - Comme neuf
EUR 18,00
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Etat : As New. Signed Copy . Inscribed by author on front endpage.
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Vendeur : Optimon Books, Gravesend, KENT, Royaume-UniOptimon Books
Contacter le vendeurVendeur avec une évaluation de 5 étoilesEtat: Occasion - Assez bon
EUR 114,21
EUR 21,01 expéditionExpédition depuis Royaume-Uni vers Etats-UnisQuantité disponible : 1 disponible(s)
Hardcover. Etat : Very Good. THERE ARE NO TARIFFS OR CUSTOMS DUTIES ON BOOKS. Hit and Lead Profiling: Identification and Optimization of Drug-like Molecules by Bernard Faller & Laszlo Urban eds.Includes inscription to 'Humphrey' by Laszlo UrbanMethods and Principles in Medicinal Chemistry, Vol. 43The only reference on current me…thods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new drug molecules before actual drug development, the two equally important aspects of pharmacological (ADME) and safety (toxicity) profiling are covered in separate parts. The ADME section covers the profiling of basic physicochemical parameters, such as solubility and permeability, as well as more complex traits, such as the likelihood of drug-drug interactions, metabolic clearance and protein binding properties. The toxicology part addresses, among others, recent advances in early genetic toxicity testing, bioactivation screening, organ-specific toxicity assays for liver, heart, kidney and blood, as well as profiling for autoimmune reactions. By addressing both drug efficiency and drug safety, this modern practical reference shows readers how each individual aspect figures in shaping the key decisions on which the entire drug development process hinges. In short, this is a complete toolbox for assessing the risk/benefit ratio for any novel compound during the early drug development stages, using both in vitro and in silico methods. Both editors are based at one of the leading research-driven pharmaceutical companies, and the authors have been recruited from numerous other global players in the field. Invaluable know-how for every medicinal chemist and drug developer.In good condition with clean pages inside. Front free endpaper is inscribed with dedication in blue ink. Copyright © Wiley-VCH.
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Vendeur : Basi6 International, Irving, TX, Etats-UnisBasi6 International
Contacter le vendeurVendeur avec une évaluation de 5 étoilesEtat: Neuf
EUR 152,41
Frais de port gratuitsExpédition nationale : Etats-UnisQuantité disponible : 1 disponible(s)
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
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Vendeur : Mispah books, Redhill, SURRE, Royaume-UniMispah books
Contacter le vendeurVendeur avec une évaluation de 4 étoilesEtat: Occasion - Comme neuf
EUR 244,08
EUR 29,18 expéditionExpédition depuis Royaume-Uni vers Etats-UnisQuantité disponible : 1 disponible(s)
Hardcover. Etat : Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
