Kobayashi daniel (25 résultats)

Etat : New.

Etat : As New. Unread book in perfect condition.

Paperback. Etat : New. Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which osimertinib has been the widely accepted as first-line therapy. Despite survival improvement seen with osimertinib and its efficacy against acquired T790M mutation, resistance through on-target and off-target pathways eventually develop. This Element describes the structural biology and pathophysiology of EGFR-mutant NSCLC and discusses past, current, and future treatment options in the metastatic, neoadjuvant, and adjuvant settings. It describes the biology and recently approved treatment for EGFR-exon 20 insertion mutation and the treatment for the uncommon exon 18 (G719X), 20 (S768I), and 21 (L861Q) mutations. It also outlines the promising clinical applications of circulating tumor DNA (ctDNA).…

Etat : New.

paperback. Etat : Fair. Wear on edges and corners.Clean pages with no markings. Ships same day in most cases!Any queries, just ask for photos. Your satisfaction matters.

paperback. Etat : Very Good. Softcover. Bound in matte pictorial paper. Cover is neat and clean. Binding is tight and secure. Pages are crisp, clean, and bright. Images printed in B&W. 348 pages. Rutgers University Press. Copyright page dated 2020. A very nice copy. We ship everyday from a real neighborhood bookstore. This description is written by an actual person, who is holding the book in front of them to make sure it's properly described. Please contact us with questions or if you would like to see photographs.…

paperback. Etat : New.

Etat : New. 1st edition NO-PA16APR2015-KAP.

Etat : New.

Paperback. Etat : Brand New. 75 pages. 8.94x5.98x0.24 inches. In Stock.

Etat : As New. Unread book in perfect condition.

Soft cover. Etat : Near Fine. 1st Edition. Stiff gray textured wraps, lettered in red and black. Joint exhibition of the Library of Congress and the Yomiuri Shumbun, 15 June-15 Sept. 1984. Mild binding lean, otherwise virtually as issued. 187 pp., illus. w/ color plates, b&w photos, etc. Size: 4to - over 9¾" - 12" tall. Book. …

Kartoniert / Broschiert. Etat : New. Inhaltsverzeichnis1.Structural biology and mechanism of activation of EGFR 2. EGFR-associated oncogenesis 3. Tyrosine kinase inhibitors (TKIs) as targeted treatment for EGFR-mutant NSCLC 4. EGFR-TKIs as adjuvant or neoadjuvant therapy.

Paperback. Etat : New. Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which osimertinib has been the widely accepted as first-line therapy. Despite survival improvement seen with osimertinib and its efficacy against acquired T790M mutation, resistance through on-target and off-target pathways eventually develop. This Element describes the structural biology and pathophysiology of EGFR-mutant NSCLC and discusses past, current, and future treatment options in the metastatic, neoadjuvant, and adjuvant settings. It describes the biology and recently approved treatment for EGFR-exon 20 insertion mutation and the treatment for the uncommon exon 18 (G719X), 20 (S768I), and 21 (L861Q) mutations. It also outlines the promising clinical applications of circulating tumor DNA (ctDNA).…

Taschenbuch. Etat : Neu. Neuware.

631 (1) pages on thick medium-glossy paper, mainly colour-illustrated throughout. - Publisher's illustrated hardcover-binding with colour-illustr. dustjacket in the col.-ill. strong cardboard-slipcase; Folio (ca. 38 x 26 x 6 cm; ca. 5,7 kg.!). ~~~ [HERBSTVERKAUF bis 05.11.2026 / AUTUMN-SALE until November 05, 2026: um 25% REDUZIERTER PREIS / PRICE-REDUCTION of 25%; ursprünglicher Preis / previously EUR 48,-] --- FIRST EDITION, OVERSIZE HEAVY HARDCOVER ORIGINAL WITH DUSTJACKET AND SLIPCASE. - One Corner of the dustjacket minimally rubed; ELSE IN BEST CONDITION, LIKE NEW.…

Etat : New. Print on Demand.

Etat : New. PRINT ON DEMAND.

PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Paperback. Etat : new. Paperback. Quantum Mechanics for the Entanglement Era is a complete graduate course in quantum mechanics that treats entanglement and quantum information as a natural extension of the postulates - not a bolted-on final chapter. Across 16 chapters, it builds the full traditional formalism (Hilbert space, operators, time evolution, angular momentum, the hydrogen atom, symmetry, perturbation theory and scattering), then carries that same machinery directly into density matrices, Bell inequalities, measurement theory, and finally qubits, quantum algorithms, error correction, and quantum communication protocols like BB84 and quantum teleportation.Every worked example is carried through to a fully solved, boxed final answer with each algebraic step shown on its own line - no skipped steps, no "left to the reader." Every end-of-chapter problem is solved in full as well, making this a genuine self-study text, not just a lecture companion. A Mathematical Reference appendix collects the linear algebra, special functions, and integrals used throughout. Written for graduate students, advanced undergraduates, and quantum information researchers who need one rigorous volume spanning both the classical formalism and the concepts driving today's quantum computing and communication research.What's insideFoundations (Ch. 1-4): the postulates of quantum mechanics built up from Hilbert space and Dirac notation; Hermitian and unitary operators, commutators, and the generalized uncertainty principle; the time-dependent and time-independent Schroedinger equations across the Schroedinger, Heisenberg, and interaction pictures, with Ehrenfest's theorem; exact solutions for the infinite/finite square well, the harmonic oscillator via both analytic and ladder-operator methods, and barrier tunnelingAngular momentum, symmetry, and the hydrogen atom (Ch. 5-7): orbital angular momentum and spherical harmonics, spin-1/2 and the Pauli matrices, addition of angular momenta via Clebsch-Gordan coefficients; the full separation-of-variables solution of the hydrogen atom and its quantum numbers; symmetry groups, the quantum-mechanical Noether correspondence, and discrete symmetries (parity, time reversal)Approximation methods (Ch. 8-9): non-degenerate and degenerate time-independent perturbation theory, the variational method, Fermi's golden rule, and an introduction to scattering theory and cross sectionsMany-body and open-system physics (Ch. 10-11): the symmetrization postulate, Slater determinants and exchange interactions for identical particles, plus the density-matrix formalism, reduced density matrices, decoherence, and the Lindblad master equation for open quantum systemsEntanglement and measurement (Ch. 12-13): the Schmidt decomposition, the EPR paradox, Bell's theorem and the CHSH inequality with experimental tests, projective and POVM measurements, the quantum Zeno effect, and a survey of interpretationsQuantum information (Ch. 14-16): qubits and the Bloch sphere, quantum gates and circuits, the no-cloning theorem, superdense coding and teleportation; the Deutsch-Jozsa and Grover algorithms, an overview of Shor's algorithm, and stabilizer/surface codes for error correction; BB84 and E91 quantum key distribution, quantum repeaters, and the current hardware landscapeAppendix A - Mathematical Reference: the linear algebra, special functions (Legendre, Hermite, Laguerre polynomials, spherical harmonics), and integrals used throughout, cross-referenced back to the chapters that use them This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Etat : New. Print on Demand.

Paperback. Etat : new. Paperback. Quantum Mechanics for the Entanglement Era is a complete graduate course in quantum mechanics that treats entanglement and quantum information as a natural extension of the postulates - not a bolted-on final chapter. Across 16 chapters, it builds the full traditional formalism (Hilbert space, operators, time evolution, angular momentum, the hydrogen atom, symmetry, perturbation theory and scattering), then carries that same machinery directly into density matrices, Bell inequalities, measurement theory, and finally qubits, quantum algorithms, error correction, and quantum communication protocols like BB84 and quantum teleportation.Every worked example is carried through to a fully solved, boxed final answer with each algebraic step shown on its own line - no skipped steps, no "left to the reader." Every end-of-chapter problem is solved in full as well, making this a genuine self-study text, not just a lecture companion. A Mathematical Reference appendix collects the linear algebra, special functions, and integrals used throughout. Written for graduate students, advanced undergraduates, and quantum information researchers who need one rigorous volume spanning both the classical formalism and the concepts driving today's quantum computing and communication research.What's insideFoundations (Ch. 1-4): the postulates of quantum mechanics built up from Hilbert space and Dirac notation; Hermitian and unitary operators, commutators, and the generalized uncertainty principle; the time-dependent and time-independent Schroedinger equations across the Schroedinger, Heisenberg, and interaction pictures, with Ehrenfest's theorem; exact solutions for the infinite/finite square well, the harmonic oscillator via both analytic and ladder-operator methods, and barrier tunnelingAngular momentum, symmetry, and the hydrogen atom (Ch. 5-7): orbital angular momentum and spherical harmonics, spin-1/2 and the Pauli matrices, addition of angular momenta via Clebsch-Gordan coefficients; the full separation-of-variables solution of the hydrogen atom and its quantum numbers; symmetry groups, the quantum-mechanical Noether correspondence, and discrete symmetries (parity, time reversal)Approximation methods (Ch. 8-9): non-degenerate and degenerate time-independent perturbation theory, the variational method, Fermi's golden rule, and an introduction to scattering theory and cross sectionsMany-body and open-system physics (Ch. 10-11): the symmetrization postulate, Slater determinants and exchange interactions for identical particles, plus the density-matrix formalism, reduced density matrices, decoherence, and the Lindblad master equation for open quantum systemsEntanglement and measurement (Ch. 12-13): the Schmidt decomposition, the EPR paradox, Bell's theorem and the CHSH inequality with experimental tests, projective and POVM measurements, the quantum Zeno effect, and a survey of interpretationsQuantum information (Ch. 14-16): qubits and the Bloch sphere, quantum gates and circuits, the no-cloning theorem, superdense coding and teleportation; the Deutsch-Jozsa and Grover algorithms, an overview of Shor's algorithm, and stabilizer/surface codes for error correction; BB84 and E91 quantum key distribution, quantum repeaters, and the current hardware landscapeAppendix A - Mathematical Reference: the linear algebra, special functions (Legendre, Hermite, Laguerre polynomials, spherical harmonics), and integrals used throughout, cross-referenced back to the chapters that use them This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by recognized authorities in their fieldsProviding a comprehensive and up-to-date review in topicClassic seriesResin glycosides are part of a very extensive family of secondary metabolites known as glycolipids or lipo-oligos.…

Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by recognized authorities in their fieldsProviding a comprehensive and up-to-date review in topicClassic seriesResin glycosides are part of a very extensive family of secondary metabolites known as glycolipids or lipo-oligos.…