birkhäuser basel birkhäuser basel jun 1990 (5 résultats)

Taschenbuch. Etat : Neu. Neuware Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 92 pp. Deutsch.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This monograph contains a collection of 16 papers that were presented at the confer ence 'Free Boundary Problems: Numerical 7reatment and Optimal Control', held at the Mathematisches Forschungsinstitut Oberwolfach, West Germany, July 9-15, 1989. It was the aim of the organizers of the meeting to bring together experts from different areas in the broad field of free boundary problems, where a certain emphasis was given to the numerical treatment and optimal control of free boundary problems. However, during the conference also a number papers leading to important new theoretical insights were presented. The strong connection between theory and applications finds its reflection in this monograph which contains papers of high theoretical and numerical interest, as well as applications to important practical problems. Many of the contributions are concerned with phase transition phenomena, a field which was of particular importance during the meeting; topics like spinodal decomposition, shape memory alloys, crystal growth and flow through porous media are addressed. Another field of major interest during the con ference was fluid flow; also this field is addressed in this volume. The volume opens with a contribution by H. W. Alt and I. Pawlow. In their paper the problem of spinodal decomposition is treated in the non-isothermal situation. For the first time the existence of a weak solution to the corresponding system of evolution equations could be proved. The results of some numerical experiments are also reported. In the following paper, M. Bornert and I.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 288 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -A Safety Considerations Genomie sequencing involves a number oj hazard ous steps, such as high eurrent, high voltage, radioaetive and highly toxie chemieals. It is, the- jore, absolutely essential that the instruetions oj equipment manu/aeturers bejollowed and that par tieular attention is paid to the loeal and jederal safety regulations. I Introduction 13 B Introduction Hypomethylation ofDNA has been positively correlated with thc activation of many eucaryotic genes. During the transition from inactive to active genes changes in the protein/DNA interaction pattern occur. Tran scriptional activation of eucaryotic genes is mediated by specific interac tions oftransacting factors with their respective DNA binding sites in Lhe control regions (promoters, enhancers) ofthe genes. This process is ofLen accompanied by changes in local chromatin strucLure, witnessed by the appearance of nuclease hypersensitive sites, as weil as by changes in protein-DNA interactions and, in the case of higher eucaryotes, alterations ofthe cytosine methylation pattern. The sole available experimental tech nique that permits the study ofthe latter phenomena at single nucleotide resolution is direct genomic sequencing/footprinting, pioneered by Church and Gilbert (1984). This method combines the chemical DNA sequencing procedure of Maxam amI Gilbert (1980) with thc detection 01' DNA sequences by electroblotting and indirect end-Iabeling by hybridiza tl0n. An alternative possibility is the novel procedure (Saluz and . lost, 1989), using Taq polymerase. The first steps 01' both meLhods are essen tially the same: total genomic DNA is digested wiLh a suilable restriction enzyme and the resulting DNA fragments are chemically sequeneed.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 288 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph contains a collection of 16 papers that were presented at the confer ence 'Free Boundary Problems: Numerical 7reatment and Optimal Control', held at the Mathematisches Forschungsinstitut Oberwolfach, West Germany, July 9-15, 1989. It was the aim of the organizers of the meeting to bring together experts from different areas in the broad field of free boundary problems, where a certain emphasis was given to the numerical treatment and optimal control of free boundary problems. However, during the conference also a number papers leading to important new theoretical insights were presented. The strong connection between theory and applications finds its reflection in this monograph which contains papers of high theoretical and numerical interest, as well as applications to important practical problems. Many of the contributions are concerned with phase transition phenomena, a field which was of particular importance during the meeting; topics like spinodal decomposition, shape memory alloys, crystal growth and flow through porous media are addressed. Another field of major interest during the con ference was fluid flow; also this field is addressed in this volume. The volume opens with a contribution by H. W. Alt and I. Pawlow. In their paper the problem of spinodal decomposition is treated in the non-isothermal situation. For the first time the existence of a weak solution to the corresponding system of evolution equations could be proved. The results of some numerical experiments are also reported. In the following paper, M. Bornert and I. 276 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 92 pp. Deutsch.