Cold spring harbor perspective (16 résultats)

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-, and various growth factors, is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues. The expert contribut…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -Parkinson's Disease is an incurable neurodegenerative disease characterized by a progressive loss of dopaminergic neurons that leads to slowness of movement, muscle rigidity, and tremors. Insoluble aggregates of proteins such as alpha-synuclein accumulate in the affected ne…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -The transplantation of organs such as the heart, kidney, and lungs is an important means of replacing seriously damaged or diseased body parts. However, a transplanted organ may fail if the recipient's immune system mounts a response to it. Transplant patients are usually p…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -The main task of Tolerance is to reorient discussions in democratic theory so as better to theorize how tolerance can operate as an active force in the context of deep pluralism. The objective is to develop a theory of active tolerance attentive to the many different ways i…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -This volume includes contributions covering each of the main junction types as well as the more specialized junctions of neuronal and immune cells. It covers their assembly and structure, importance in signal transduction, and roles in development, normal tissue homeostasis…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -In sexually reproducing organisms, germ cells give rise to gametes and serve as the link between generations. A key event during germ cell development is the decision to leave mitosis and enter meiosis, leading to the formation of mature eggs and sperm. Germ cell developmen…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -Studies of mammary gland biology are critically important given the prevalence of breast cancer. This organ represents an excellent model system for research into developmental mechanisms, gene regulation, tissue organization, hormonal action, secretion, and stem cell biolo…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -Wnt proteins are signaling molecules that play critical roles during embryonic development and in the regeneration of adult tissues. They bind to Frizzled and LRP family receptors on the cell surface, triggering a series of events that cause -catenin to enter the nucleus an…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -The basic biology of the HIV virus provides a model for a more general understanding of retroviruses, and the worldwide epidemic of AIDS makes research into the disease process and potential therapies among the most critical in biomedical science. This book explores work on…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and ef…

Gebundene Ausgabe. Etat : Wie neu. Gebraucht - Wie neu -The endoplasmic reticulum (ER) is an extensive network of membranes that folds, modifies, and transports proteins in eukaryotic cells. It also manufactures lipids and interacts extensively with other organelles, playing essential roles in cell growth and homeostasis. Writte…