springer basel birkhäuser basel mai 2000 (4 résultats)

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For the first time in the mathematical literature this two-volume work introduces a unified and general approach to the asymptotic analysis of elliptic boundary value problems in singularly perturbed domains. While the first volume is devoted to perturbations of the boundary near isolated singular points, this second volume treats singularities of the boundary in higher dimensions as well as nonlocal perturbations.At the core of this book are solutions of elliptic boundary value problems by asymptotic expansion in powers of a small parameter that characterizes the perturbation of the domain. In particular, it treats the important special cases of thin domains, domains with small cavities, inclusions or ligaments, rounded corners and edges, and problems with rapid oscillations of the boundary or the coefficients of the differential operator. The methods presented here capitalize on the theory of elliptic boundary value problems with nonsmooth boundary that has been developed in the past thirty years. Moreover, a study on the homogenization of differential and difference equations on periodic grids and lattices is given. Much attention is paid to concrete problems in mathematical physics, particularly elasticity theory and electrostatics.To a large extent the book is based on the authors' work and has no significant overlap with other books on the theory of elliptic boundary value problems. 323 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For the first time in the mathematical literature this two-volume work introduces a unified and general approach to the asymptotic analysis of elliptic boundary value problems in singularly perturbed domains. This first volume is devoted to domains whose boundary is smooth in the neighborhood of finitely many conical points. In particular, the theory encompasses the important case of domains with small holes. The second volume, on the other hand, treats perturbations of the boundary in higher dimensions as well as nonlocal perturbations. The core of this book consists of the solution of general elliptic boundary value problems by complete asymptotic expansion in powers of a small parameter that characterizes the perturbation of the domain. The construction of this method capitalizes on the theory of elliptic boundary value problems with nonsmooth boundary that has been developed in the past thirty years. Much attention is paid to concrete problems in mathematical physics, for example in elasticity theory. In particular, a study of the asymptotic behavior of stress intensity factors, energy integrals and eigenvalues is presented.To a large extent the book is based on the authors' work and has no significant overlap with other books on the theory of elliptic boundary value problems. 435 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. Yet, we have much to learn about the integration of these powerful techniques with information from genomics, proteomics, computation and pharmacokinetics before dramatic increases in the drug discovery/development processes can be achieved. The chapters in this book represent the state of the art regarding the integration of combinatorial chemistry and HTS in connection with anti-inflammatory targets. Obviously, there is much work to be done beyond what is described in this text, nevertheless, it should set the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating inflammatory diseases. 258 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chromosomes Today, Volume 13 includes the plenary lectures presented atthe 13th International Chromosome Conference, covering the most recentadvances in the studies on chromosomes. The contributions in this volumewere presented by some of the world's leaders in cytogenetic andmolecular research and outline the present status of knowledge on thecomposition, structure, function and evolution of chromosomesincluding, among others, the advancement of the human genome project.The use of cytogenetic studies has greatly increased in the last fewyears, resulting in a progressive improvement in the available methodsthat has consequently allowed a more detailed analysis of the molecularorganization of eukaryotic chromosomes and a precise in situlocalisation of specific gene sequences. This volume of ChromosomesToday provides up-to-date information regarding the topics at theforefront of chromosome research: genetic regulation, imprinting, DNAduplication, meiotic pairing, and the regulation of the.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 368 pp. Englisch.