Springer jul 2007 (424 résultats)

Buch. Etat : Neu. Neuware -Themodernbillion-dollardrug-discoveryprocessstronglyreliesonbothhi- throughput synthesis and screening methods. Whereas the latter is based on molecular biological methods, the ef cient and reliable generation of c- pound collections often makes use of combinatorial chemistry. Discovered in the 1980s, this methodology was explored extensively in the 1990s by groups in academia and in industry. Without any doubt, combinatorial chemistry changed the whole drug-discovery process and found many applications in cropscience and the material sciences. However, since its implementation, solution- and solid-phase techniques have been competing with each other, and although many companies started theircombinatorialchemistryprogramwithsolid-phasetechniques,soluti- phase combinatorial methods have taken over and now account for appro- mately 25% of all combinatorial efforts. The syntheses of complex, non-polymeric structures, discovered in the 1960s by the late Bruce Merri eld, was largely ignored in the context of solid supports, mainly due to the fact that appropriate synthesis techniques were not available. Since solid-phase chemical methodology strongly differs from traditional solution-phase chemistry, two chapters deal with this topic. The Bräse group (Jung, Wiehn, Bräse) gives an overview of multifunctional linkers, which can beusedforthegenerationofdiversity-orientedcollections,simplybycleavage fromresins. Still in its infancy, solid-phase reactions employ simple amide chemistry in most cases due to their high-yielding, reliable protocols. Ljungdahl, Br- eld, and Kann address solid-phase organometallic chemistry, which is now one ofthe great challenges in reliable solid-phase organicsynthesis. 376 pp. Englisch.…

Buch. Etat : Neu. Neuware -Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen. 492 pp. Deutsch.…

Buch. Etat : Neu. Neuware -Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen. 490 pp. Deutsch.…

Buch. Etat : Neu. Neuware -Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen.…

Buch. Etat : Neu. Neuware -Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 492 pp. Deutsch.…

Buch. Etat : Neu. Neuware - Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen.…

Buch. Etat : Neu. Neuware -Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehörige bzw. Selbsthilfegruppen berichten über praxisbezogene Maßnahmen zur Lösung von leichteren bis schwerwiegenden Problemen, die mit dem Älterwerden verbunden sind. Die Themenkreise spannen sich von stationären und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, Österreich und der Schweiz ergänzt. Alle Kapitel wurden neu strukturiert und überarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehörigen einen praxisrelevanten Überblick zur Betreuung und Versorgung von älteren Menschen. 492 pp. Deutsch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Topological K-theory is one of the most important invariants for noncommutative algebras equipped with a suitable topology or bornology. Bott periodicity, homotopy invariance, and various long exact sequences distinguish it from algebraic K-theory.We describe a bivariant K-theory for bornological algebras, which provides a vast generalization of topological K-theory. In addition, we discuss other approaches to bivariant K-theories for operator algebras. As applications, we study K-theory of crossed products, the Baum-Connes assembly map, twisted K-theory with some of its applications, and some variants of the Atiyah-Singer Index Theorem. 262 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a thorough and comprehensive treatment of irregular wavelet frames. It introduces and employs a new notion of affine density as a highly effective tool for examining the geometry of sequences of time-scale indices. Coverage includes non-existence of irregular co-affine frames, the Nyquist phenomenon for wavelet systems, and approximation properties of irregular wavelet frames. 156 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These historical narratives of scientific behavior reveal the often irrational way scientists arrive at and assess their theories. There are stories of Einstein's stubbornness leading him to reject a correct interpretation of an experiment and miss an important deduction from his own theory, and Newton missing the important deduction from one of his most celebrated discoveries. This enlightening book clearly demonstrates that the greatest minds throughout history arrived at their famous scientific theories in very unorganized ways and they often did not fully grasp the significance and implications of their own work. 228 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During medical training there are certain tasks that are not taught at medical school nor in the common reference books. There are some skills that medical students are expected to learn by 'osmosis'. These skills are never officially taught or examined in medical school, butare, however, a fundamental part of being a safe, good and efficient doctor. This book includes 'golden rules' or important points to remember and case examples, both of which are given as displayed extracts.This book will help the junior doctor unlock their potential and improve their performance, cutting the time it takes to achieve certain medical objectives. It is meant to fill in the gaps where the medical school and clinical guides stop. It gives the reader the information needed to organise themselves so that they can hit the ground running. It is not intended as a clinical survival guide, but more a friendly hand to allow the reader to get ahead in medicine and how to keep on track and develop a career path. 120 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Eigenvectors of graph Laplacians have not, to date, been the subject of expository articles and thus they may seem a surprising topic for a book. The authors propose two motivations for this new LNM volume: (1) There are fascinating subtle differences between the properties of solutions of Schrödinger equations on manifolds on the one hand, and their discrete analogs on graphs. (2) 'Geometric' properties of (cost) functions defined on the vertex sets of graphs are of practical interest for heuristic optimization algorithms. The observation that the cost functions of quite a few of the well-studied combinatorial optimization problems are eigenvectors of associated graph Laplacians has prompted the investigation of such eigenvectors.The volume investigates the structure of eigenvectors and looks at the number of their sign graphs ('nodal domains'), Perron components, graphs with extremal properties with respect to eigenvectors. The Rayleigh quotient and rearrangement of graphs form the main methodology. 120 pp. Englisch. …

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a straightforward and easy-to-follow introduction to the basic techniques involved with using Renderman. Packed with illustrations and hands-on examples, it will serve as an excellent foundation, a good first step and overview of the program. The book explains how scenes are described; illustrates how to create surfaces, color, lighting, shadows, and depth of field using RIB and the C API; and introduces the techniques involved in creating shaders and applying textures. This second edition includes a new chapter on global illumination. 300 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dual-use technological writing at its best. This book presents HTML and JavaScript in a way that uniquely meets the needs of students in both engineering and the sciences. The author shows how to create simple client-side applications for scientific and engineering calculations. Complete HTML/JavaScript examples with science/engineering applications are used throughout to guide the reader comprehensively through the subject. The book gives the reader a sufficient understanding of HTML and JavaScript to write their online applications. This book emphasises basic programming principles in a modern Web-oriented environment, making it suitable for an introductory programming course for non-computer science majors. It is also ideal for self-study. 216 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book applies the concept of synchronization to security of global heterogeneous and hetero-standard systems by modeling the relationship of risk access spots (RAS) between advanced and developing economies network platforms. The proposed model is more effective in securing the electronic security gap between these economies with reference to real life applications, such as electronic fund transfer in electronic business. This process involves the identification of vulnerabilities on communication networks. This book also presents a model and simulation of an integrated approach to security and risk known as Service Server Transmission Model (SSTM). 220 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers a clear, accessible exploration of lifelong learning and educational opportunities for women in higher education. It has been developed from work undertaken by members of the Women in Higher Education Network with chapters organized in three thematic sections: Ambivalent Positions in the Academy, Process and Pedagogy at Work, Career - Identity - Home. 260 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book brings together experts on national history writing from all five continents to discuss the role of history in the making of national identities in a transnational and comparative way. The institutionalization and professionalisation of history writing is analysed in the context of history's increasing nationalization. 243 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This title offers insight into a range of art and performance practices that have emerged as a result a more technological world. These practices are integral to alternative and mainstream performance culture and the author explores their aesthetic theorisation and analyses other approaches, including those offered by research into neuroesthetics. 220 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Statistical analysis of stock markets and foreign exchange markets has demonstrated the intermittent nature of economic time series. A nonlinear model of business cycles is able to simulate intermittency arising from order-chaos and chaos-chaos transitions. This monograph introduces new concepts of unstable periodic orbits and chaotic saddles, which are unstable structures embedded in a chaotic attractor and responsible for economic intermittency. 116 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Despite the inroads made by women in the professions, the glass ceiling remains a persistent barrier to their career progression. Using a range of interactional sociolinguistic data this publication investigates the crucial role that gendered discourses play in perpetuating workplace gender inequalities. 236 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book explores the intersections of film, justice, and the state in comparative perspective across a range of major Asian countries, including India, China, Japan, Korea, the Philippines, and Vietnam. The contributing authors cross the conventional border between the analysis of on-screen and off-screen intersections of law and cinema. 239 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Drawing on case studies, this collection offers international perspectives on how community media serves their audiences. The contributors present perspectives on the ever-burgeoning area of grassroots. Their research represents participant observation, hands-on community involvement, boards of directors, content analysis, and ethical inquiries. 258 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications. 144 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the refereed proceedings of the 19th International Conference on Computer Aided Verification. Thirty-three state-of-the-technology papers are presented, together with fourteen tool papers, three invited papers, and four invited tutorials. All the current issues in computer aided verification and model checking-from foundational and methodological issues to the evaluation of major tools and systems-are addressed. 584 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Researchers and professionals in the relevant fields will find this book a must-read, as it defines the leading edge of current research into conceptual structures. It constitutes the refereed proceedings of the 15th International Conference on Conceptual Structures, held in Sheffield, UK in July 2007. With almost 50 papers contained in its 500 pages, it includes a special focus on the application of conceptual structures in business and technological settings and is organized into topical sections for ease of reference. 532 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this comprehensive introduction to software measurement, Ebert and Dumke detail knowledge and experiences about the subject in an easily understood, hands-on presentation. The book describes software measurement in theory and practice as well as provides guidance to all relevant measurement tools and online references. In addition, it presents hands-on experience from industry leaders and provides many examples and case studies from Global 100 companies. Besides the many practical hints and checklists, readers will also appreciate the large reference list, which includes links to metrics communities where project experiences are shared. 576 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book reveals the full extent of electricity's significance in Nineteenth and early Twentieth Century literature and culture. It provides in-depth coverage of a wide range of canonical American authors from the American Renaissance onwards. As well as many fascinating hitherto under-studied writers. 251 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book stages a series of interventions and inventions of urban space between 1880 and 1930 in key literary texts of the period. Making sharp distinctions between modernity and modernism, the volume reassesses the city as a series of singular sites irreducible to stable identities, concluding with an extended reading of The Waste Land . 262 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A new and original analysis of the mission undertaken by FDR's Secretary of State during the Phoney War, Rofe's work explains the motivations and goals of Roosevelt through an analysis of the president's foreign policy and of the nature of the Anglo-American relationship of the time. 270 pp. Englisch.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This bold new reading of Orwell's work focuses upon his representation of communities and the myths that shape them. It analyzes his interpretations of class, gender and nationality within the context of the period. The book uses a range of texts to argue that Orwell attempted to integrate 'traditional' communal identities with socialist politics. 225 pp. Englisch.…