Springer okt 2011 (Plus de 7 200 résultats)

Taschenbuch. Etat : Neu. Neuware -1 Groups.- 2 Graphs.- 3 Chemical Compounds.- 4 Asymptotic Evaluation of the Number of Combinations.- The Legacy of Pólya's Paper: Fifty Years of Pólya Theory.- References.

Taschenbuch. Etat : Neu. Neuware -The importance of international liner shipping needs little emphasizing. A large majority of international trade moves by sea, and the liner shipping share in total freight revenue exceeds one-half. Notwithstanding, people in general know surprisingly little about the basic facts of the liner shipping industry, and, in particular, about the economics ofliner shipping. Perhaps because it is an international industry, where shipping lines flying many different flags participate, it has tended to fall in between national accounts of domestic industries. Even transport economists have, generally speaking, treated liner shipping rather 'stepmotherly'; besides the work of Bennathan and Walters (1969), a relatively small group of specialized maritime economists, including A. Stromme-Svendsen, T. Thorburn, S. Sturmey, R. Goss, and B. M. Deakin, have in the post-war period made important contributions to the subject, but so far no coherent and reasonably comprehensive treatise of liner shipping economics has appeared. The first purpose of the present volume is therefore obvious: to provide just that. The book is divided in three parts: Part I The liner shipping industry; Part II Liner service optimization; Part III Economic evaluation of the conference system. Needless to say, all three parts concur to fulfill the first purpose of providing a complete book of liner shipping economics. In Part II a more or less separate, second, purpose has been to develop analytical tools for liner service optimization. Thereby we use different approaches.…

Taschenbuch. Etat : Neu. Neuware -Automation has been employed for many years to provide a multitude of reasonably priced products for the American consumer. However, it has become evident that its real character as a manufacturing systems approach needs to be examined carefully for a better appreciation. In this book the purpose is to examine automation technology in its broadest sense and develop not only an understanding but also present some of the engineering and organization 'know-how' by which manufacturing management can more effectively utilize automation to improve pro ductivity and combat rising costs in the years ahead. Fundamentally, this book is addressed to manufacturing managers, and the material presented in a manner that will provide the knowledge for assuring success in automating. In addition, it highlights the man ufacturing research and long-range planning that will be required for creating the new manufacturing technology so necessary for assuring success in future automation efforts. One of the important facts emphasized in this text is that automation is not merely robotics ar another kind or type of machinery. To effect true productivity improvement requires a fresh look at the entire pro duction process or facility-as a completely integrated system. With the developments of the past few years, rapid advances in the technology and the 'tools of automation' have brought this imperative goal within the reasonable grasp of manufacturing management in almost every segment of industry. However, to utilize this progress, it is necessary to acquire a working understanding of all facets of automation.…

Taschenbuch. Etat : Neu. Neuware -The book is intended for graduate or postgraduate students in actuarial science and probability as well as for working actuaries with background in probability. To make the book self-contained, surveys are given on Markov processes, martingales and point processes. It also contains an introduction to traditional risk theory. …

Taschenbuch. Etat : Neu. Neuware -Many historians have concerned themselves with the founding of the German Empire in 1871 and the means used to unite the disparate sections of Germany, many of which had older traditions than did Bismarck's Prussia. Understandably writers have given more attention to the victor than to the vanquished. Except for polemicists who seek to prove the wrong done or to vindicate the action taken, scholars have been interested in writing about trends which were to become significant in the new Reich, about the new governmental structure itself, and about the diplomacy and statesmanship which were used to form the new German nation-state. But the consolidation of many diverging strands of political, economic, and social traditions in the new state left many issues unsolved and in fact seemed to create new ones. Many of these problems, while not overtly affecting the basic outline of German history, have nonetheless influenced it and have become at times serious matters of concern for the Reich Chancellor. One of the problems was the threat of particularist sentiment to the national unity which Bismarck was trying to create. Although there was an awareness among some nineteenth century Ger mans of a specific German nationality, the majority of people did not think in terms of a German unity but regarded themselves as Bavarians, Saxons, or belonging to some other Stamm, or tribal subdivision of the Germans.…

Taschenbuch. Etat : Neu. Neuware -The design and assessment of modern high temperature plant demands an understanding of the creep and rupture behaviour of materials under multi axial stress states. Examples include thread roots in steam turbine casing bolts, branch connections in nuclear pressure vessels and blade root fixings in gas or steam turbine rotors. At one extreme the simple notch weakening/notch strengthening characterization of the material by circumferentially vee-notched uniaxial rupture tests, as specified in many national standards, may be sufficient. These were originally intended to model thread roots and their conservatism is such that they frequently are considered adequate for design purposes. At the other extreme full size or model component tests may be employed to determine the safety margins built into design codes. This latter approach is most commonly used for internally pressurized components, particularly where welds are involved. However, such tests are extremely expensive and the use of modern stress analysis techniques combined with a detailed knowledge of multiaxial properties offers a more economic alternative. Design codes, by their nature, must ensure conservatism and are based on a material's minimum specified properties. In the case of high temperature components the extension of life beyond the nominal design figure, say from 100000 to 200000 h, offers very significant economic benefits. However, this may require a more detailed understanding of the multiaxial behaviour of a specific material than was available at the design stage.…

Taschenbuch. Etat : Neu. Neuware -The course of history is never one of smooth progression. Periods of relative quietness are interrupted by periods of wars and revolution. This pattern resembles that of a river which, before flowing into the delta, has to pass countless rapids. The same holds for the development of the science of medicine. In obstetrics some of these 'revolutions' or 'rapids' consist of the introduction of conservative obstetrical treatment by Lucas Johann Boer at the beginning of the nineteenth century, the discovery of the cause of puerperal sepsis by Oliver Wendell Holmes and Semmelweiss between 1843 and 1847, the introduction of the principle of asepsis by Pasteur in 1874, the introduction of prenatal care at the end of the nine teenth and the beginning of the twentieth century (Mijnlieff, Treub, De Snoo), the improvement of surgical techniques, the possibility to treat shock by bloodtransfusion, and, finally, the acquisition of new means for the effective therapy of infection. All these developments have led to a sharp reduction of maternal and perinatal mortality. In this connection it must be pointed out that such a reduction could never have been accomplished without the favourable social changes as a result of which medical and prenatal care could be made universally available. In recent years there has been another revolutionary develop ment in obstetrics. Two factors have been responsible for this: the ap plication of basic sciences in obstetrics, and the dissolution of the isolation with respect to other clinical disciplines.…

Taschenbuch. Etat : Neu. Neuware -Technology transfer has a long history, but only recently has it become the subject of study and action. The rapid rate of scientific and technical advance in both Europe and the United States and the existence of large technology gaps among nations has brought the importance of the process into sharper focus, and has c~used technology transfer to have implications for countless aspects of both national and international develop ment. Technology transfer has been variously defined as: the process of information transfer between science, technology and actual utilization of scientific data and ideas, to wit: production of goods and services; the process by which science and technology are diffused throughout human activity; the transfer of research results into operations; the process by which technical information originating in one setting is adapted for use in another setting. Collectively, these and other definitions share a common theme which characterizes the process as one of bringing technology i'ilto widespread use in solving mankind's problems in the shortest practical time. The first NATO Advanced Study Institute (ASI) on Technology Transfer in July, 1973, brought together many of the individuals dealing with quantitative data, based on empirical research. This conference had both the advantages and disadvantages of a somewhat detached point of view. The ASI also had lectures contributed by representatives from government agencies and corporations (and a few university-based scholars) who had been active as practitioners or consultants in policy-making and organizational design for technology transfer.…

Taschenbuch. Etat : Neu. Neuware -During the last 20 years two groups of investigators have concerned themselves with the problem of acid-base regulation at various body temperatures. Each group, in professional isolation, pursued a separate path. Surgeons and anesthe tists developed techniques and tools for hypothermic cardio-pulmonary by-pass operations and based their rationale for acid-base management on in vitro models of blood behavior. Physiologists and biochemists, on the other hand, endeavored to understand acid-base regulation in living organisms naturally subjected to changes in body temperature. Only in the last decade has there been an increasing awareness that each group could benefit from the other's experiences. With this goal in mind members of both groups were invited to present their views and observations in the hope of arriving at a better understanding of acid-base management during hypothermia and gaining a greater insight into the factors which control acid-base regulation during normothermia. This led to the presen tation of the present volume with the aim of providing the clinician with a survey of present theories and the resulting strategies for management of the hypother mic patient. Acknowledgment The editors express their great appreciation to Miss Augusta Dustan for her dedicated effort in the preparation and editing of the manuscripts. Contributors Heinz Becker, M. D. Department of Surgery, University of California Medical Center, Los An geles, Los Angeles, CA 90024, U. S. A. Gerald D. Buckberg, M. D. Department of Surgery, University of California Medical Center, Los An geles, CA 90024, U. S. A.…

Taschenbuch. Etat : Neu. Neuware.

Buch. Etat : Neu. Neuware -Ein Blauwal ist groß - aber wie groß Wie viele Eiffeltürme ist der Mount Everest hoch Wie viele Olympiaschwimmbecken fasst ein Supertanker Wie viele Posaunen erzeugen denselben Lärm wie ein Donnerschlag Höher, größer, schneller - und origineller: Humorvoll und kenntnisreich geschrieben, fesselt Wie viele Elefanten wiegt ein Blauwal den Leser mit reich bebilderten Betrachtungen über Flächen, Höhen, Gewichte, Geschwindigkeiten und vieles mehr. Noch nie hat Messen so viel Spaß gemacht! 128 pp. Deutsch.…

Buch. Etat : Neu. Neuware -Ein Blauwal ist groß - aber wie groß Wie viele Eiffeltürme ist der Mount Everest hoch Wie viele Olympiaschwimmbecken fasst ein Supertanker Wie viele Posaunen erzeugen denselben Lärm wie ein Donnerschlag Höher, größer, schneller - und origineller: Humorvoll und kenntnisreich geschrieben, fesselt Wie viele Elefanten wiegt ein Blauwal den Leser mit reich bebilderten Betrachtungen über Flächen, Höhen, Gewichte, Geschwindigkeiten und vieles mehr. Noch nie hat Messen so viel Spaß gemacht! 128 pp. Deutsch.…

Taschenbuch. Etat : Neu. Neuware.

Taschenbuch. Etat : Neu. Neuware - The importance of international liner shipping needs little emphasizing. A large majority of international trade moves by sea, and the liner shipping share in total freight revenue exceeds one-half. Notwithstanding, people in general know surprisingly little about the basic facts of the liner shipping industry, and, in particular, about the economics ofliner shipping. Perhaps because it is an international industry, where shipping lines flying many different flags participate, it has tended to fall in between national accounts of domestic industries. Even transport economists have, generally speaking, treated liner shipping rather 'stepmotherly'; besides the work of Bennathan and Walters (1969), a relatively small group of specialized maritime economists, including A. Stromme-Svendsen, T. Thorburn, S. Sturmey, R. Goss, and B. M. Deakin, have in the post-war period made important contributions to the subject, but so far no coherent and reasonably comprehensive treatise of liner shipping economics has appeared. The first purpose of the present volume is therefore obvious: to provide just that. The book is divided in three parts: Part I The liner shipping industry; Part II Liner service optimization; Part III Economic evaluation of the conference system. Needless to say, all three parts concur to fulfill the first purpose of providing a complete book of liner shipping economics. In Part II a more or less separate, second, purpose has been to develop analytical tools for liner service optimization. Thereby we use different approaches.…

Taschenbuch. Etat : Neu. Neuware - During the last 20 years two groups of investigators have concerned themselves with the problem of acid-base regulation at various body temperatures. Each group, in professional isolation, pursued a separate path. Surgeons and anesthe tists developed techniques and tools for hypothermic cardio-pulmonary by-pass operations and based their rationale for acid-base management on in vitro models of blood behavior. Physiologists and biochemists, on the other hand, endeavored to understand acid-base regulation in living organisms naturally subjected to changes in body temperature. Only in the last decade has there been an increasing awareness that each group could benefit from the other's experiences. With this goal in mind members of both groups were invited to present their views and observations in the hope of arriving at a better understanding of acid-base management during hypothermia and gaining a greater insight into the factors which control acid-base regulation during normothermia. This led to the presen tation of the present volume with the aim of providing the clinician with a survey of present theories and the resulting strategies for management of the hypother mic patient. Acknowledgment The editors express their great appreciation to Miss Augusta Dustan for her dedicated effort in the preparation and editing of the manuscripts. Contributors Heinz Becker, M. D. Department of Surgery, University of California Medical Center, Los An geles, Los Angeles, CA 90024, U. S. A. Gerald D. Buckberg, M. D. Department of Surgery, University of California Medical Center, Los An geles, CA 90024, U. S. A.…

Taschenbuch. Etat : Neu. Neuware - Technology transfer has a long history, but only recently has it become the subject of study and action. The rapid rate of scientific and technical advance in both Europe and the United States and the existence of large technology gaps among nations has brought the importance of the process into sharper focus, and has c~used technology transfer to have implications for countless aspects of both national and international develop ment. Technology transfer has been variously defined as: the process of information transfer between science, technology and actual utilization of scientific data and ideas, to wit: production of goods and services; the process by which science and technology are diffused throughout human activity; the transfer of research results into operations; the process by which technical information originating in one setting is adapted for use in another setting. Collectively, these and other definitions share a common theme which characterizes the process as one of bringing technology i'ilto widespread use in solving mankind's problems in the shortest practical time. The first NATO Advanced Study Institute (ASI) on Technology Transfer in July, 1973, brought together many of the individuals dealing with quantitative data, based on empirical research. This conference had both the advantages and disadvantages of a somewhat detached point of view. The ASI also had lectures contributed by representatives from government agencies and corporations (and a few university-based scholars) who had been active as practitioners or consultants in policy-making and organizational design for technology transfer.…

Taschenbuch. Etat : Neu. Neuware - The design and assessment of modern high temperature plant demands an understanding of the creep and rupture behaviour of materials under multi axial stress states. Examples include thread roots in steam turbine casing bolts, branch connections in nuclear pressure vessels and blade root fixings in gas or steam turbine rotors. At one extreme the simple notch weakening/notch strengthening characterization of the material by circumferentially vee-notched uniaxial rupture tests, as specified in many national standards, may be sufficient. These were originally intended to model thread roots and their conservatism is such that they frequently are considered adequate for design purposes. At the other extreme full size or model component tests may be employed to determine the safety margins built into design codes. This latter approach is most commonly used for internally pressurized components, particularly where welds are involved. However, such tests are extremely expensive and the use of modern stress analysis techniques combined with a detailed knowledge of multiaxial properties offers a more economic alternative. Design codes, by their nature, must ensure conservatism and are based on a material's minimum specified properties. In the case of high temperature components the extension of life beyond the nominal design figure, say from 100000 to 200000 h, offers very significant economic benefits. However, this may require a more detailed understanding of the multiaxial behaviour of a specific material than was available at the design stage.…

Taschenbuch. Etat : Neu. Neuware - The course of history is never one of smooth progression. Periods of relative quietness are interrupted by periods of wars and revolution. This pattern resembles that of a river which, before flowing into the delta, has to pass countless rapids. The same holds for the development of the science of medicine. In obstetrics some of these 'revolutions' or 'rapids' consist of the introduction of conservative obstetrical treatment by Lucas Johann Boer at the beginning of the nineteenth century, the discovery of the cause of puerperal sepsis by Oliver Wendell Holmes and Semmelweiss between 1843 and 1847, the introduction of the principle of asepsis by Pasteur in 1874, the introduction of prenatal care at the end of the nine teenth and the beginning of the twentieth century (Mijnlieff, Treub, De Snoo), the improvement of surgical techniques, the possibility to treat shock by bloodtransfusion, and, finally, the acquisition of new means for the effective therapy of infection. All these developments have led to a sharp reduction of maternal and perinatal mortality. In this connection it must be pointed out that such a reduction could never have been accomplished without the favourable social changes as a result of which medical and prenatal care could be made universally available. In recent years there has been another revolutionary develop ment in obstetrics. Two factors have been responsible for this: the ap plication of basic sciences in obstetrics, and the dissolution of the isolation with respect to other clinical disciplines.…

Taschenbuch. Etat : Neu. Neuware - Many historians have concerned themselves with the founding of the German Empire in 1871 and the means used to unite the disparate sections of Germany, many of which had older traditions than did Bismarck's Prussia. Understandably writers have given more attention to the victor than to the vanquished. Except for polemicists who seek to prove the wrong done or to vindicate the action taken, scholars have been interested in writing about trends which were to become significant in the new Reich, about the new governmental structure itself, and about the diplomacy and statesmanship which were used to form the new German nation-state. But the consolidation of many diverging strands of political, economic, and social traditions in the new state left many issues unsolved and in fact seemed to create new ones. Many of these problems, while not overtly affecting the basic outline of German history, have nonetheless influenced it and have become at times serious matters of concern for the Reich Chancellor. One of the problems was the threat of particularist sentiment to the national unity which Bismarck was trying to create. Although there was an awareness among some nineteenth century Ger mans of a specific German nationality, the majority of people did not think in terms of a German unity but regarded themselves as Bavarians, Saxons, or belonging to some other Stamm, or tribal subdivision of the Germans.…

Taschenbuch. Etat : Neu. Neuware - In 1937 there appeared a paper that was to have a profound influence on the progress of combinatorial enumeration, both in its theoretical and applied aspects. Entitled Kombinatorische Anzahlbest immungen jUr Gruppen, Graphen und chemische Verbindungen, it was published in Acta Mathematica, Vol. 68, pp. 145 to 254. Its author, George Polya, was already a mathematician of considerable stature, well-known for outstanding work in many branches of mathematics, particularly analysis. The paper in Question was unusual in that it depended almost entirely on a single theorem -- the 'Hauptsatz' of Section 4 -- a theorem which gave a method for solving a general type of enumera tion problem. On the face of it, this is not something that one would expect to run to over 100 pages. Yet the range of the applica tions of the theorem and of its ramifications was enormous, as Polya clearly showed. In the various sections of his paper he explored many applications to the enumeration of graphs, principally trees, and of chemical isomers, using his theorem to present a comprehen sive and unified treatment of problems which had previously been solved, if at all, only by ad hoc methods. In the final section he investigated the asymptotic properties of these enumerational results, bringing to bear his formidable insight as an analyst.…

Taschenbuch. Etat : Neu. Neuware -This book is intended to present group representation theory at a level accessible to mature undergraduate students and beginning graduate students. This is achieved by mainly keeping the required background to the level of undergraduate linear algebra, group theory and very basic ring theory. Module theory and Wedderburn theory, as well as tensor products, are deliberately avoided. Instead, we take an approach based on discrete Fourier Analysis. Applications to the spectral theory of graphs are given to help the student appreciate the usefulness of the subject. A number of exercises are included. This book is intended for a 3rd/4th undergraduate course or an introductory graduate course on group representation theory. However, it can also be used as a reference for workers in all areas of mathematics and statistics. 172 pp. Englisch.…

Taschenbuch. Etat : Neu. Neuware -This book is intended to present group representation theory at a level accessible to mature undergraduate students and beginning graduate students. This is achieved by mainly keeping the required background to the level of undergraduate linear algebra, group theory and very basic ring theory. Module theory and Wedderburn theory, as well as tensor products, are deliberately avoided. Instead, we take an approach based on discrete Fourier Analysis. Applications to the spectral theory of graphs are given to help the student appreciate the usefulness of the subject. A number of exercises are included. This book is intended for a 3rd/4th undergraduate course or an introductory graduate course on group representation theory. However, it can also be used as a reference for workers in all areas of mathematics and statistics. 172 pp. Englisch.…

Taschenbuch. Etat : Neu. Neuware -This book is intended to present group representation theory at a level accessible to mature undergraduate students and beginning graduate students. This is achieved by mainly keeping the required background to the level of undergraduate linear algebra, group theory and very basic ring theory. Module theory and Wedderburn theory, as well as tensor products, are deliberately avoided. Instead, we take an approach based on discrete Fourier Analysis. Applications to the spectral theory of graphs are given to help the student appreciate the usefulness of the subject. A number of exercises are included. This book is intended for a 3rd/4th undergraduate course or an introductory graduate course on group representation theory. However, it can also be used as a reference for workers in all areas of mathematics and statistics.…

Taschenbuch. Etat : Neu. Neuware - A specialist in hand surgery will not be available at all hospitals for some years. In the meantime, the fate of the patient will continue to rest in the hands of the surgeon who first treats him. It is essential, therefore, that both the novice and the accomplished surgeon have a sound grasp of the diagnostic and therapeutic fundamentals of hand surgery. The material in this book is presented in a clear, practical manner by a general surgeon who has successfully practiced hand surgery; the result is an especially useful and rewarding book. Many acute situations in hand surgery are not as complicated as they appear to be, whereas other problems can be handled only after much study and experience. Based on his experience with over 7000 general and emergency opera- tions yearly at the Ludwigshafen Surgical Clinic and after years of inten- sive work in the field of hand surgery, my medical chief, Dr. H. R. Mittelbach, has taken the time and trouble to write this handbook for general and clinical practice. For the practicing surgeon and especially the resident, the most important aspects of the treatment of hand injuries have been presented in a clear, concise manner. The didactic excellence of the material, its novel format, and the simple yet forceful drawings that obviate lengthy text descriptions enable the reader to become quickly oriented. However, the book is more thanjust a 'cookbook' for quick reference.…

Taschenbuch. Etat : Neu. Neuware - This book is intended to provide a treatment of the production, properties and applications of X-rays suitable for undergraduate courses in physics. It is hoped that parts of it, at least, will be useful to students on other courses in physics, materials science, metallurgy, chemistry, engineering, etc. at various levels. It is also hoped that parts of it will serve as an introduction to the subject of X-ray crystallography, and to this end the treatment of X-ray diffraction has been designed to show the relation between the simple approach and the more sophisticated treatments. During many years of teaching this subject to Degree, Diploma in Technology and Higher National Certificate students, I have been unable to find a single book which attempts to cover the whole of this field. This lack of a treatment of X-rays and their applications in one volume has prompted me to attempt to fill the gap and this present volume is the result. Obviously in writing such a book I have referred to many existing books and I acknowledge my indebtedness to the authors of all the books which I have used. I believe that all these books are included in the re- ferences at the ends of the chapters but if I have omitted any, then my apologies are offered to the authors concerned. …

Taschenbuch. Etat : Neu. Neuware - The original Beecham Manual for General Practice was produced by Dr Selwyn Carson, of Christchurch, New Zealand, whose objective was a set of instructions for patient care for his practice team. Beecham Research Laboratories published and distributed it. Dr Ed Gawthorn of Melbourne, Australia, edited an Australian version again published and distributed by Beecham Research Laboratories. We were invited to adapt the New Zealand and Australian editions for British readers -but we decided that we should produce an entirely new Manual. This was done and it was published and distributed to general practitioners by Beecham Research Laboratories. This latest edition has been revised and updated. The Manual is a ready reference on planned care of certain age groups and situations; specific procedures and emergencies; and clinical care in general practice of important conditions. We have intentionally adopted a concise didactic style that should be helpful for trainers, trainees and members of the practice team. We thank Beecham Research Laboratories, and especially Ed Stanford and Bill Burns, for their support and help over many years. John Fry (Editor) June 1982 viii Section A PLANNED CARE Family Planning A1 Discuss with the individual patient the advantages and disadvantages of all the methods. Keep in mind individual needs, wishes and religious beliefs. In Great Britain - 2.5 million women are registered with their G.P.'s for contraception. -100 per G.P. - 95% of G.P.'s provide contraceptive services.…

Taschenbuch. Etat : Neu. Neuware - Evolutionary Biology, of which this is the twenty-second volume, continues to offer its readers a wide range of original articles, reviews, and commentaries on evolution, in the broadest sense of that term. The topics of the reviews range from anthropology, molecular evolution, and paleobiology to principles of systematics. In recent volumes, a broad spectrum of articles have appeared on such subjects as asymmetric sexual isolation, biochemical systematics in plants, species selection, DNA hybridization and phylogenetics, modes of evolution in Pleistocene rodents, and development and evolution of the vertebrate limb. We have also attempted to provide a forum for con flicting ideas. Articles such as these, often too long for standard journals, are the material for Evolutionary Biology. The editors continue to solicit manuscripts on an international scale in an effort to see that everyone ofthe many facets of biological evolution is covered. Manuscripts should be sent to anyone of the following: Max K. Hecht, Department of Biology, Queens College of the City University of New York, Flushing, New York 11367; Bruce Wallace, Department of Biology, Virginia Polytechnic Institute and State University, Blacks burg, Virginia 24061; GhilleanT. Prance, New York Botanical Garden, Bronx, New York 10458. The Editors vii Contents 1. Phylogeny of Early Vertebrate Skeletal Induction and Ossification Patterns . 1 John G. Maisey Introduction: The Fossil Record. . . . . . . . . . . . . . . . 1 . …

Taschenbuch. Etat : Neu. Neuware - That residues of pesticide and other 'foreign' chemicals in food stuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of 'Residue Reviews' and by the gratifying enthusiasm, sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any seriou~ question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food tech nologists, pharmacologists, toxicologists, and changing pest-control requfrements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and tOXicological disciplines.…

Taschenbuch. Etat : Neu. Neuware - In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition. This has indeed been the case and the current edition reflects these new advances. Our picture of the structure of the fatty acid synthetase has changed dramatically, bringing a new concept in enzymology - the multicatalytic polypeptide chain. This new knowledge owes much to the exploitation of genetic mutants, the use of which is undoubtedly going to extend into many other areas of lipid biochemistry. An understanding of the control of lipid metabolism has also advanced considerably during the last decade and we have tried to reflect that here, although it will be some years before a truly integrated picture can be obtained. For this reason we have continued to deal with the control of particular aspects of lipid metabolism - fatty acids, triacylglycerols, lipoprotein- in the specific chapters but we can foresee the time when a chapter on the overall integration of lipid metabolism will be appropriate and feasible. As a particular example, the exciting new concepts of the control of cholesterol metabolism in specific tissues via the interaction of low density lipoproteins with cell surface receptors have been described in Chapter 6.…

Taschenbuch. Etat : Neu. Neuware - Worldwide concern in scientific, industrial, and governmental com munities over traces of toxic chemicals in foodstuffs and in both abiotic and biotic environments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published progress reports, and archival documentations. These three publications are integrated and scheduled to provide in international communication the coherency essential for nonduplicative and current progress in a field as dynamic and complex as environmental contamination and toxicology. Until now there has been no journal or other publication series reserved exclusively for the diversified literature on 'toxic' chemicals in our foods, our feeds, our geographical surroundings, our domestic animals, our wild life, and ourselves. Around the world immense efforts and many talents have been mobilized to technical and other evaluations of natures, locales, magnitudes, fates, and toxicology of the persisting residues of these chemicals loosed upon the world. Among the sequelae of this broad new emphasis has been an inescapable need for an articulated set of authorita tive publications where one could expect to find the latest important by this emerging area of science together with world literature produced documentation of pertinent ancillary legislation.…