Springer us apr 2012 (347 résultats)

Taschenbuch. Etat : Neu. Neuware -Statistics is of ever-increasing importance in Science and Technology and this book presents the essentials of the subject in a form suitable either as the basis of a course of lectures or to be read and/or used on its own. It assumes very little in the way of mathematical knowledge-just the ability to substitute numerically in a few simple formulae. However, some mathematical proofs are outlined or given in full to illustrate the derivation of the subject; these can be omitted without loss of understanding. The book does aim at making clear the scope and nature of those essential tests and methods that a scientist or technologist is likely to need; to this end each chapter has been divided into sections with their own subheadings and some effort has been made to make the text unambiguous (if any reader finds a misleading point anywhere I hope he will write to me about it). Also with this aim in view, the equality of probability to proportion of population is stated early, then the normal distribution and the taking of samples is discussed. This occupies the first five chapters. With the principles of these chapters understood, the student can immediately learn the significance tests of Chapter 6 and, if he needs it, the analysis of variance of Chapter 7. For some scientists this will be most of what they need. Howcver, they will be in a position to read and/or use the remaining chapters without undue difficulty.…

Taschenbuch. Etat : Neu. Neuware - Examination of the tables of contents of journals - biochemical, molecular biological, ultrastructural, and physiological-provides convincing evidence that membrane biology will be in the 1970s what biochemical genetics was in the 1960s. And for good reason. If genetics is the mechanism for main taining and transmitting the essentials of life, membranes are in many ways the essence of life. The minimal requirement for independent existence is the individualism provided by the separation of 'life' from the environment. The cell exists by virtue of its surface membran~. One might define the first living organism as that stage of evolution where macromolecular catalysts or self-reproducing polymers were first segregated from the surrounding milieu by a membrane. Whether that early membrane resembled present cell membranes is irrelevant. What matters is that a membrane would have provided a mechanism for maintaining a local concentration of molecules, facilitating chemical evolution and allowing it to evolve into biochemical evolution. That or yet more primitive membranes, such as a hydrocarbon monolayer at an air-water interface, could also have provided a surface that would facilitate the aggregation and specific orientation of molecules and catalyze their interactions. If primitive membranes were much more than mere passive barriers to free diffusion, how much more is this true of the membranes of contemporary forms of life. A major revolution in biological thought has been the recogni tion that the cell, and especially the eukaryotic cell, is a bewildering maze of membranes and membranous organelles.…

Taschenbuch. Etat : Neu. Neuware - This volume is the third in the Contemporary Geriatric Medicine series. As in previous volumes, information is presented in the form of easy-to read essays to bring the reader up to date on state-of-the-art develop ments in the area of geriatric medicine. Once again, a system approach is utilized. In addition, several new topics-including alcoholism, throm boembolic disease, and decubitus ulcer management-have been intro duced to enhance this volume's usefulness to the busy clinician and student. Each chapter is not meant to be an exhaustive review of all topics in the field, but rather to focus on issues currently receiving a great deal of attention. Our goal continues to be to create an exciting approach to contemporary issues in geriatric medicine. The editors are once again appreciative for having been given the opportunity to develop this series. Appreciation is also expressed to our professional colleagues, families, and administrative assistants, who have enabled this volume to reach fruition. As in the past, we thank, most of all, our elderly patients for providing the inspiration and impetus to improve our knowledge and understanding of the health care needs of the elderly. Steven R. Gambert, M.D. V alhalla, New York ix Contents Chapter 1 Geriatric Cardiology and Blood Pressure 1 Edmund H. Duthie, Jr., and Michael H. Keelan, Jr.…

Taschenbuch. Etat : Neu. Neuware - Epithelial cells are present in many different tissues in the body, and possess a diverse number of functional properties. However, all epithelial cells share some common characteristics. The cells possess a morphological polarity (an-apical and basolateral surface), and are interconnected by tight junctions. The epithelial cells also possess the capacity to transport select solutes across the monolayer. Transport systems localized on either the apical or basolateral surface are respon sible for this vectorial transport. Such characteristics of epithelial cells can be examined in the tissue culture situation. This volume discusses the use of cell culture techniques to study these fundamental properties of epithelial cells. Ma jor questions concerning epithelia which may be examined in culture are ad dressed. The approaches which are taken to answer these questions are described in detail with regards to kidney cell cultures. Similar investigations may be done with epithelial cell cultures derived from other tissues, following the kidney cell culture paradigm.…

Taschenbuch. Etat : Neu. Neuware - The Conference on Emerging Priorities in Ceramic Engineer ing and Science, held at Alfred University, November 4-6, 1974, was arranged to provide a basis for reassessment of professional goals, procedures and outlook. American priorities among comfort, safety, national prestige, security, convenience and environmental quality are significantly different from those of a dozen years ago. Economic factors have shifted, as exempli fied by scarcities in energy, mate rials and world food supplies. At the same time, demands for safer products, healthier work ing conditions and fairer rules of behavior are making them selves felt. Governmental, corporate and consumer interests are all involved and they are intricately inte rrelated. Higher education, for its part, must not only respond wisely to changing student attitude, itself a part of the national scene, but must gain perspective toward the present and toward changes of yet unknown nature which can be expected in the future. Persistent and pointed questions from engineers, managers, and students were an indication to us of wide-spread concern to understand the new pattern of priorities that is presently emerging. In response to this need, Conference papers were invited from distinguished engineers, scientists, and other specialists; their willingness to contribute from their expertise and their thinking is very much appreciated by the editors. The first four chapters of the volume deal with the larger scene and with the viewpoints of those concerned with it in behalf of government, corporations and the professions. …

Taschenbuch. Etat : Neu. Neuware - Volume 6 of Cerebral Cortex is in some respects a continuation of Volume 2, which dealt with the functional aspects of cortical neurons from the physiological and pharmacological points of view. In the current volume, chapters are devoted to the catecholamines, which for a number of reasons were not represented in the earlier volume, and to acetylcholine and the neuropeptides, about which much new information has recently appeared. Volume 6 deals in part with the structure and function of cholinergic and catecholaminergic neuronal systems in the cerebral cortex and with new aspects of the cortical peptidergic neurons, notably the almost universal propensity of the known cortical peptides for being colocalized with classical transmitters and with one another. It thus completes our coverage of the major cortical neuro transmitter and neuromodulatory systems. Other chapters in this volume deal with data pertaining to the proportions of different types of cells and synapses in the neocortex and the physiology of the cortical neuroglial cells. These latter are topics that rarely receive separate treatment and the current chapters serve again to continue discussions of subjects that were introduced in Volume 2. The previous volumes have all been devoted to the neocortex but the present one introduces the subject of the archicortex. To this end, separate chapters are devoted to the physiology and anatomy of the hippocampal formation. …

Taschenbuch. Etat : Neu. Neuware - When Dr. Katherine Tansley's 'Vision in Vertebrates' appeared in 1965, it filled a real void that had hitherto existed. It did so by serving at once as a text-book: for an undergraduate course, a general introduction to the subject for post-graduate students embarking on research on some aspect of vision, and the interested non-specialists. Gordon Walls' 'The Vertebrate Eye and It. s Adaptive Radiation' and A. Rochon-Duvigneaud's 'Les Yeux et la Vision des Vertebres' have served as important sources of information on the subject and continue to do so even though it is 40 years since they appeared. However, they are essentially specialised reference works and are not easily accessible to boot. The genius of Katherine Tansley was to present in a succinct (132 pages) and lucid way a clear and an interesting survey of the matter. Everyone liked it, particularly the students because one could read it quickly and understand it. Thus, when it seemed that a new edition was desirable, especially in view of the enormous strides made and the vast literature that had accumulated in the past 20 years, one of us (MAA) asked Dr. Tansley if she would undertake the task. Since she is in retirement and her health not in a very satisfactory state both she and her son, John Lythgoe (himself a specialist of vision), asked us to take over the task.…

Taschenbuch. Etat : Neu. Neuware - The aim of the editors of this volume is to use basic and ap plied studies in the field of mutagenesis to approach a problem of especial concern. The problem is that of the usage of toxic chemi cals, particularly agricultural chemicals, in ever-increasing quan tities in those parts of the world that feed the most people. Agri cultural chemicals that are in use in Pakistan are emphasized here. These are the same chemicals that are in use throughout the develop ing world, although the quantities of the different types that are used may vary from country to country, and from region to region within countries. A number of these chemicals can no longer be sold in Europe or in the United States, and it is often difficult to iden tify a scientific reason as to why they are sold at all. It is ironic that toxic chemicals are used as a humanitarian device to rid the world of Pestilence and Famine -- two of the Horsemen of the Apocalypse. If we do not wish poisonous chemicals to become the fifth Horseman of the Apocalypse, then we must begin now to identify and regulate the large-scale usage of toxic sub stances everywhere.…

Taschenbuch. Etat : Neu. Neuware - Hemoglobin and the red cell have continued to set a dizzying pace as the objects of research in the two and one-half year interval since the First International Conference on Red Cell Metabolism and Function. Most exciting perhaps, is a beginning molecular attack on sickle cell disease. The story of the inter action of red cell metabolism and oxygen transport has continued to unfold, and we can now infer that patients with hypoxia usually utilize red cell metabolic adjustments to improve oxygenation. This puts the red cell squarely in the center of medical practice, since much of medicine-heart, pulmonary, and blood disease- deals with inadequate oxygenation. On April 27th through the 29th, 1972, crystallographers, chemists, biochemists, physiologists, geneticists, and physi cians from many medical disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor to present new data, to review recent developments, and to try to piece together additional features of the red cell puzzle. The meeting was dedicated to Dr. Francis John Worsley Roughton, Professor Emeritus of Colloid Science, University of Cambridge, England, in recognition of his numerous excellent contributions to the understanding of hemoglobin and red cell function. The program got off to a good start with a paper from M. F. Perutz, Nobel Laureate, on the structure of hemoglobin. Dr.…

Taschenbuch. Etat : Neu. Neuware - Anyone who has any contact with mental patients, old or young, or their families, or just visits a mental hospital or school for the retarded, is aware of the tremendous suffering caused by malfunctioning of the brain. The func tion of no other organ is so crucial for our everyday life, our proper func tioning, indeed our happiness, and no other illness causes as much anguish to patients or their families as mental illness. It is surprising and sad, therefore, how little effort has been devoted to research in this area; more so because such research is the only hope to ameliorate this suffering, or, to speak in the language of politics or economics, to decrease the enormous sums that we spend on trying to help our patients, with what is must generally be agreed are the most primitive and inadequate methods of treatment. Clearly, since functions of the brain are vital not only in illness, but in health, pathology is not the only area of concern to neurochemists, but it is an area that urgently needs neurochemical contributions. Progress in this field has been slower than in other areas of neurochemistry, and it seems that solutions in this field are very elusive. The reason for this is that the experimental approach is especially difficult in conditions specific for humans, or specific for complex behavior.…

Taschenbuch. Etat : Neu. Neuware - Allen I. Laskin Biosciences Research Exxon Research and Engineering Company Linden, New Jersey I was contacted in the Fall of 1981 by Professors Martin Dworkin and Palmer Rogers, of the University of Minnesota and asked to participate in the orgnization of the 1983 conference in the series, 'Interface Between Biology and Medicine'. They and the other members of the advisory committee had the vision to realize that this was a time to depart somewhat from the traditional theme, since one of the major areas of interest in the biological and related sciences these days is that of biotechnology in a broader sense than its impact on medicine alone. In designing the format of the Conference, we considered another factor. There has been a plethora of conferences, symposia, and meetings on biotechnology over the past few years, and the faces and topics have become rather familiar. There has been a strong emphasis on the development of the technology and the 'biotechnology industry'; less attention has been paid to the science behind it. One might get the impression from some of these meetings and from the popular press that biotechnology has just recently sprung up, apparently full blown; the very fundamental scientific discoveries and the great body of 1 ALLEN I. LASKIN 2 continuing research that forms that basis for the technology is often obscured.…

Taschenbuch. Etat : Neu. Neuware - The International Thermal Conductivity Conference was started in 1961 with the initiative of Mr. C. F. Lucks and grew out of the needs of researchers in the field. From 1961 to 1973 the Confer ences were held annually, and have been held biennially since 1975 when our Center for Information and Numerical Data Analysis and Synthesis (CINDAS) of Purdue University became the permanent Spon sor of the Conferences. These Conferences provide a broadly based forum for researchers actively working on the thermal conductivity and closely related properties to convene on a regular basis to ex change their ideas and experiences and report their findings and results. The Conferences have been self-perpetuating and are an example of how a technical community with a common purpose can transcend the invisible, artificial barriers between disciplines and gather togeth er in increasing numbers without the need of national publicity and continuing funding support, when they see something worthwi1e going on. It is believed that this series of Conferences not only will grow stronger, but will set an example for researchers in other fields on how to jointly attack their own problem areas.…

Taschenbuch. Etat : Neu. Neuware - Metal ions and proteins are ubiquitous. Therefore, not surprisingly, new protein-metal interactions continue to be dis covered, and their importance is increasingly recognized in both physical and life sciences. Because the subject matter is so broad and affects so many disciplines, in organizing this Symposium, I sought participation of speakers with the broadest possible range of interests. Twenty-two accepted my invitation. To supplement the verbal presentations, the Proceedings include five closely re lated invited contributions. The ideas expressed are those of the various authors and are not necessarily approved or rejected by any agency of the United States Government. No official recommendation concerning the sub ject matter or products discussed is implied in this book. This book encompasses many aspects of this multifaceted field. Topics covered represent biochemical, immunochemical, bioorganic, biophysical, metabolic, nutritional, medical, physiological, toxi cological, environmental, textile, and analytical interests. The discoveries and developments in any of these areas inevitably illumine others. I feel that a main objective of this Symposium, bringing together scientists with widely varied experiences yet with common interests in protein-metal interactions, so that new understanding and new ideas would result has been realized. I hope that the reader enjoys and benefits from reading about the fascinat ing interactions of metal ions and proteins as much as I did.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Becoming a Food Scientist is designed as a reservoir of ideas for those beginning a graduate education in food science or beginning a professional career in the field. Although at times it may read as a how-to manual for success in graduate school, it is meant to encourage each reader to study the research process, to challenge conventional wisdom, and to develop a career path that maximizes the probability of success both in school and beyond. The author has viewed food science graduate programs through the lenses of programs at four universities and service in numerous activities with the Institute of Food Technologists. This book is thus focused on the field of food science, but it may have relevance to other scientific disciplines. The book introduces the concept of research as process in the first chapter. Subsequent chapters focus on individual unit operations of research: idea generation, problem definition, critical evaluation of the literature, method selection, experimental design, data collection, processing and analysis, and knowledge dissemination. Successful graduate students in food science must master each of these operations. The final section of the book pushes the reader beyond graduate school into its practice in the real world. Topics covered in the maturation of a food scientist include the scientific meeting, critical thinking, science and philosophy, ethics, finding and managing the literature, planning, grantsmanship, laboratory setup and management, and career development. This book should be a meaningful companion for any graduate student in the field and those transitioning from graduate school to the food science profession. 180 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the last 50 years there have been an increasing number of applications of algebraic tools to solve problems in communications, in particular in the fields of error-control codes and cryptography. More recently, broader applications have emerged, requiring quite sophisticated algebra - for example, the Alamouti scheme in MIMO communications is just Hamilton's quaternions in disguise and has spawned the use of PhD-level algebra to produce generalizations. Likewise, in the absence of credible alternatives, the industry has in many cases been forced to adopt elliptic curve cryptography. In addition, algebra has been successfully applied to problems in signal processing such as face recognition, biometrics, control design, and signal design for radar. This book introduces the reader to the algebra they need to appreciate these developments and to various problems solved by these techniques. 60 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I am pI eased to present to the readers the Proceedings of the Second International Congress on Myocardial and Cellular Bioenerge tics and Compartmentation which was held in Los Angeles during February 16-18, 1984. I would I ike to express my deep appreciation to all those who have encouraged us to hold the Second International Congress. This endeavor could not have been possible without the generous finan cial support of the following: The American Society for Magnesium Research, The University of Southern California Department of Con tinuing Medical Education, Alpha Therapeutics, ALSEB Scientific Products, The American Physiological Society, Ciba-Geigy Corpora tion, Victor Gura, M.D., Merck Sharp and Dohme, Phosphoenergetics, Stuart Pharmaceuticals, and the Upjohn Company. A note of special thanks goes to Samuel Bessman, M.D., who has been a source of constant support and encouragement for this Con gress and for my research endeavors. Nachman Brautbar vii CONTENTS I. HICROCOMPARTHENTATION AND ENERGY TRANSPORT: The Physiological Significance of the Creatine Phosphate Shuttle . . . . . . . . . . . . 696 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1974, as we approached the National Bicentennial and the Centenary of the American Chemical Society, Professor Otto Vogl, then Chairman of the Division of Polymer Chemistry, arranged a very special symposium dedicated to a review of the history of the Divi sion. It was an extraordinary occasion which included remarks by Professors Herman Mark, Charles Marvel, William Bailey, and Charles Overberger, all past Chairmen of the Division. The Executive Committee of the Division of Polymer Chemistry felt that 1976 deserved even more attention since it was to be also the 25th, the Silver Anniversary, of the Division of Polymer Chemis try. This year would be a most appropriate one not only to review milestones in our discipline, but also to look to the future. It was decided to undertake this volume and Dr. R. D. Ulrich agreed to serve as editor in assembling the collected papers. It is the hope of the officers of the Division that this volume will serve many purposes - a reference text, a record, and a source of perspective. F. E. Bailey Chairman (1976) Division of Polymer Chemistry American Chemical Society vii Contents R. D. Ulrich - The History of the ACS Division 1 of Polymer Chemistry, Inc. Bovey F. A. 31 F. R. Eirich 53 J. D. Ferry 63 P. J. Flory 69 Huggins M. L. 99 L. Mandelkern 113 123 H. F. Mark - C. S. Marvel 133 B. Maxwell 143 . 300 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The choice of title for this collective volume reflects the desire of the editors and authors to make clear that, while the bulk of the material is concerned with luminescence, other aspects of the excited state have not been excluded. In the five years which have elapsed since the publication of the classical monograph of Konev, a wealth of new information has ap peared on the emission properties of proteins and nucleic acids. Indeed, since new publications in this area appear to be proliferating in a geometric ratio, this may be the last opportunity to provide a comprehensive summary of the field in a book which is not of prohibitive length. This is what we have attempted to do here. While the orientation of each chapter naturally reflects the interests and point of view of the author, there has been a general effort to present .a critical assessment of existing results and interpretations, rather than a compendium of data with minimal comment. Finally, it should be stressed that the rapid evolution of the subject at the time of writing makes it inevitable that the book will age to some degree over the next few years, although this will occur at differing rates for the various chapters. We can only hope that most of the material in this interim summing-up will prove resistant to the erosion of time and provide a solid foundation for further progress. 504 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although microwaves and coherent optics, being two of the largest and most useful branches of electrical engineering to emerge technologically, are usually considered as distinct subjects, many of the underlying fundamental principles, scientific achievements, and practical applications have common features. Following the evolvment of the initial principles and techniques during the closing decade of the last century, microwave engineering has long matured to a stage of ready availability of components, automation and accuracy of measurement, economical manufacturing methods, and application of sophisticated systems. Further, this development of electromagnetic phenomena having spatial and temporal coherence has, based on several centuries of study and practice of noncoherent light, in the last two decades reached the optical region. Hence, it is now practicable to consider a comprehensive treatment of these two fields, division being made by subject matter rather than by the artificial distinctions of frequency and/or wavelength ranges. However, a full text on the combined subjects would be very large and unwieldy and, thus, this Bibliography is presented in the hope that it will prove useful as a compact reference source to a large body of workers and, by putting forward the latest scientific and technical advances, stimulate a multi-disciplinary approach. The material of the book commences with the fundamentals of radiation and matter, progressing through components and devices, amplification and generation, transmission, reception and processing of information, and methods of measurement to conclude with a wide range of applications. 752 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume represents the proceedings of the second international meeting on chiral separations held at the University of Surrey between the 12th and 15th of September 1989. Like the preceding meeting, it was jointly organised by the Chromatographic Society and the Robens Institute of the University of Surrey in response to the continued interest in this area of separation science. Of particular interest to the organisers was the very clear change in the nature of the delegates attending this second symposium as compared with the first. At the previous meeting the majority of the delegates were composed of chromatographers with problems in the area of chiral separations who were keen to learn as much as possible about these techniques from the handful of recognised experts in this area. In this second symposium the divide between expert and novice was much less apparent, with the latter providing many interesting and useful contributions to the scientific programme in termt; of both oral and poster presentations. 244 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the ways in which the cerebral organization of sensory sys tems in general, and the auditory system in particular, can be in vestigated is by studying defects of the perception and discrimina tion of acoustic stimuli resulting from destruction of different parts of the auditory system by a pathological focus in them or by their surgical removal. The disturbances accompanying lesions of the peripheral part of the auditory system (disturbances of sound conduction, dis turbances arising in the ha ir cells of the cochlea) are weIl known. It is much more difficult to determine the character of disturb ances specific for lesions of the central parts of the auditory sys tem and, in particular, of the auditory cortex. Types of visual disturbances in man associated with lesions of the visual cortex - homonymous hemianopia with preservation of central vision in unilateral lesions and cortical blindness in bilateral lesions - are described in the neurological literature (Brower, 1936). The visual agnosias found in lesions of the secondary visual areas and inferior temporal zones of the human and animal cortex are also weIl known. Analogous facts showing that destruction of the parietal cor tex disturbs complex (epicritic) forms of sensation but leaves more elementary sensation (protopathic) intact are described by Head. 132 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Can the art of predictive medicine anticipate the development of diabetes And if so, what can be done about it How early is early enough to intervene effectively With what therapeutic modality Why Big babies are not an infrequent occurrence in mothers with normal carbohydrate metabolism for another 10, 20, or even 30 years. The abnor mality present during pregnancy is now accepted as what is inherited with the diabetic predisposition, or what can be recognized as the diabetic susceptibility. It occurs before hyperglycemia, during the phase of dy namic resistance to diabetes, during the prediabetic period. Prediabetes means before diabetes, and was applied for the first time by Mara~on in Spain, to signify the stage before hyperglycemia. Foglia in Argentina used the term in 1944 for his pancreatectomized rats. We pub lished the first paper on humans in 1951 (Camerini-Davalos, R.A., Landabure, P., and Serantes, N., Rev Med Cordoba 39: 187). 436 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the intervening years since the publication of Volume I, the develop ment of new uses for the various types of lasers has proceeded at a rate more rapid than even the most fanciful dreamers envisioned. Of course, the main effort has been on the laser itself-new wavelengths, shorter and longer time domains for pulses, increases in power, and, most important, greater reliability. In its first stage the laser was described as a solution in search of a problem. The production of holograms was one problem whose solution seemed to involve large number of lasers. However that proposal had its own difficulties, for the hologram itself was described as a solution searching for a problem. But all of that now is a chapter from ancient history . On the current scene the laser is used in industrial pro duction lines, as a classroom item at all levels of education, and in com mercial usage such that the public is generally exposed to the laser devices themselves. Trial runs have been made, e. g. , of laser-based supermarket checkout devices and as commercial exploitation of this item begins, cer tainly many more similar adaptations will follow. However, the shift in emphasis from research usage of lasers to de velopment and production has been relative rather than absolute. The use of the laser in research has not lessened; rather it has grown at as fast a pace. Yet a similar trend is seen there also. 432 pp. Englisch. …

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When we were first approached by the senior editors of this series to edit a book on interactions between the host and infectious agents, we acceptedthis offer as an exciting challenge. The only condition, readily agreed upon, was that such a book should focus on the immunology of infections in humans. Our reasons, if not biases, were severalfold. We sensed that the fields of microbiology and im munolgy, which had diverged as each was focusing on its individual search, were coming together. In agreement with the opinions expressed by Dr. Richard Krause in the Introduction, we strongly believed that the development of the immune system evolved in response to infectious agents and that the evolution of these agents was influenced in turn by the character of the host's responses. An inten sive examination of the multitude of primitive or more recently developed host defense mechanisms to determine their relative contribution to man's resistance to a given infectious agent appeared to us to be of crucial basic and practical interest. Many immune mechanisms studied in animals were being explored in humans and it appeared timely to focus particularly on what was known about man's resistance to infectious agents, correlating this information with lessons learned from relevant experiments in animal models. 632 pp. Englisch. …

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Statistics is of ever-increasing importance in Science and Technology and this book presents the essentials of the subject in a form suitable either as the basis of a course of lectures or to be read and/or used on its own. It assumes very little in the way of mathematical knowledge-just the ability to substitute numerically in a few simple formulae. However, some mathematical proofs are outlined or given in full to illustrate the derivation of the subject; these can be omitted without loss of understanding. The book does aim at making clear the scope and nature of those essential tests and methods that a scientist or technologist is likely to need; to this end each chapter has been divided into sections with their own subheadings and some effort has been made to make the text unambiguous (if any reader finds a misleading point anywhere I hope he will write to me about it). Also with this aim in view, the equality of probability to proportion of population is stated early, then the normal distribution and the taking of samples is discussed. This occupies the first five chapters. With the principles of these chapters understood, the student can immediately learn the significance tests of Chapter 6 and, if he needs it, the analysis of variance of Chapter 7. For some scientists this will be most of what they need. Howcver, they will be in a position to read and/or use the remaining chapters without undue difficulty. 184 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1. 0 INTRODUCTION. In this chapter we define first in Section I. I the concept of failure used in this study. Thereafter, we discuss briefly the causes and possible consequ ences of failure. Finally, we explain in Section 1. 2 the aim of this study. 1. 1 THE CONCEPT OF FAILURE. In this monograph we investigate the predictability of corporate failure. By 'failure' we understand the inability of a firm to pay its obligations when these fall due (i. e. technical cash insolvency). (Walter 1957 and Donaldson 1962 and 1969). Failure mostly appears in a critical situation as a consequ ence of a sharp decline in sales. Such a decline can be caused by a recession, the loss of an important customer, shortage of a raw material, deficiencies of management, etc. The ability to predict corporate failure is important for all parties involved in the corporation, in particular for management and investors. An early warning signal of probable failure will enable them to take preventive measures: changes in operating policy or reorganization of financial structure, but also voluntary liquidation will usually shorten the period over which losses are incurred. The possibility to predict failure is important also from a social point of view, because such an event is an indication of misallocation of resources; prediction provides opportunities to take corrective measures. (See also Lev 1974, p. 134). 1. 2 AIM AND OUTLINE OF THE STUDY. 132 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Parent-Child Separation: Psychosocial Effects on Development is an abstracted bibliography dealing with the consequences of parental separation and deprivation on the developing child and adolescent. We were interested in investigating the literature pertaining to the absence of a parent for reasons other than parental death. Main topics included were maternal or paternal absence due to desertion, military duty, imprisonment, parental institutionalization and divorce. Restricted parenting articles were included when they dealt with maternal or paternal inattention, rather than physical abuse. Particular problems with being a single parent were viewed from the perspective of child development. Because of the wealth of literature available in this area it became necessary to exclude topics such as laboratory studies dealing with temporary separation, normative attachment studies, effects of maternal employment, child abuse, child institutionalization and the like. Other related topics will be the subject of forthcoming books. These include the effect of parental death on the child and problems of childhood hospitali zation. In Parent-Child Separation each of the 690 main references have abstracts which were derived from three main sources: Psycho logical Abstracts, author-supplied abstracts and those written by the authors of this book. In compiling this book it became neces sary, because of size limitations, to focus on articles published after 1960. However, several pre-1960 articles and books were im portant from a historical perspective and are included in a separate section marked 'Historical References. ' These represent important earlier contributions to this vast subject area. 372 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Eleventh Symposium on Advances in Tracer Method ology was held in Boston on October 13-14, 1966. The sym posium, which was sponsored by the New England Nuclear Corporation, commemorated the tenth anniversary of the Corporation. The Symposia on Advances in Tracer Methodology, which have been held regularly since 1957, bring together research workers in a variety of disciplines who share an interest in radioactive tracers. The four volumes, this one representing the record of the Eleventh Symposium, provide a compact and readily available source of information-much of which was usually scattered throughout the scientific literature-of inter est to biochemists, pharmacologists, endocrinologists, and analysts for whom tracers have become an indispensable tool. The editor is especially grateful to Dr. Konrad Bloch, Harvard University, and Dr. Waldo E. Cohn, Oak Ridge National Laboratory, for chairing the sessions at the Eleventh Sym posium. The cooperation of the speakers is deeply appreCiated. In addition, a special bouquet to my secretary, Mrs. Edith Thompson, for her generous assistance in arranging the various symposia and the publication of the papers. S. R. 304 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nuclei of Light Elements with a Large Excess of Neutrons Obtained in Transfer Reactions with Heavy Ions.- Ground States of Light Even-Even Nuclei.- Isomers Undergoing Spontaneous Fission.- Measuring the Magnetic Moments of Short-Lived Nuclear States.- Coulomb Interaction and Reactions between Complex Nuclei.- Methods and Results of the Nuclear Three-Body Problem.- Absorption of -Mesons and Nuclear Structure.- Nuclear Scattering of High-Energy Particles and Effective Optical Potential.- Direct Methods in the Theory of Nuclear Reactions. 148 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While this world eagerly awaits the ideal contraceptive technique that could efficiently, safely, and esthetically save this planet from the starvation and squalor of over crowding and offer women control over their reproductive capacity, the individual faced with the frustration, even des peration, induced by infertility begs for help in achieving the desired conception. The discipline of gynecology and obstetrics, recogniz ing the importance of these problems and the need for spe cial expertise in reproductive endocrinology and its atten dant clinical challenges in fertility and infertility, has now formalized the training of specialists in this area of scientific knowledge in a further effort to advance the skills of diag nosis and treatment attendant on these complex problems. Slowly but steadily, as befits the complexity of the endocrine and metabolic pathways involved, the scientific basis of reproductive physiology has been revealed by the research of physicians, biochemists, and physiologists. It is clear that no significant clinical advance can be made with out the foundation of such new knowledge. Indeed, the successful treatment of infertility resulting from failure of ovulation was based on just such a scientific advance. 316 pp. Englisch.…