springer us springer new york dez 2017 (12 résultats)

Buch. Etat : Neu. Neuware -This volume presents techniques and recently developments in extracellular recording. The chapters in this book explore topics such as mouse, rat and zebrafish models; extracellular recordings on human cognition; single-unit recordings and multi-electrode arrays; and recordings in perinatal and early developing mice. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and authoritative, Extracellular Recording Approaches is a valuable resource that provides readers with up-to-date applications and methods to study brain regions involved in sensory, motor, and cognitive functions.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 312 pp. Englisch.

Buch. Etat : Neu. Neuware -This book develops the theory of multivariable analysis, building on the single variable foundations established in the companion volume, Real Analysis: Foundations and Functions of One Variable. Together, these volumes form the first English edition of the popular Hungarian original, Valós Analízis I & II, based on courses taught by the authors at Eötvös Loránd University, Hungary, for more than 30 years. Numerous exercises are included throughout, offering ample opportunities to master topics by progressing from routine to difficult problems. Hints or solutions to many of the more challenging exercises make this book ideal for independent study, or further reading.Intended as a sequel to a course in single variable analysis, this book builds upon and expands these ideas into higher dimensions. The modular organization makes this text adaptable for either a semester or year-long introductory course. Topics include: differentiation and integration of functions of several variables; infinite numerical series; sequences and series of functions; and applications to other areas of mathematics. Many historical notes are given and there is an emphasis on conceptual understanding and context, be it within mathematics itself or more broadly in applications, such as physics. By developing the student¿s intuition throughout, many definitions and results become motivated by insights from their context.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 404 pp. Englisch.

Buch. Etat : Neu. Neuware -This text presents a highly original treatment of the fundamentals of FEM, developed using computer algebra,based on undergraduate-level engineering mathematics and the mechanics of solids. The book is divided into two distinct parts of nine chapters and seven appendices. The first chapter reviews the energy concepts in structural mechanics with bar problems, which is continuedin the next chapter for truss analysis usingMathematicaprograms.The Courant and Clough triangular elements for scalar potentials and linear elasticity are covered in chapters three and four, followed byfour-node elements. Chapters five and six describe Taig¿s isoparametric interpolants and Iron¿s patch test. Rayleigh vector modes, which satisfy point-wise equilibrium, are elaborated on in chapter seven along with successful patch tests in the physical (x,y) Cartesian frame.Chapter eight explains point-wise incompressibility and employs (Moore-Penrose) inversion of rectangular matrices. The finalchapter analyzes patch-testsin all directions and introduces five-node elements for linear stresses. Curved boundaries and higher order stresses are addressed inclosed algebraic form.Appendices give a short introduction toMathematica, followed bytruss analysis using symbolic codes that could be used in all FEM problems to assemble element matrices and solve for all unknowns. AllMathematicacodes for theoretical formulations and graphics are included with extensive numerical examples.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 372 pp. Englisch.

Buch. Etat : Neu. Neuware -This fully updated edition explores methods involving sphingosine-1-phosphate (S1P), a bioactive lysophospholipid which has become the focus of much research interest as it has widespread developmental and physio-pathological actions, controlling events within the nervous, reproductive, gastrointestinal, vascular, respiratory, and immune systems, in addition to having a prominent role in cancer, early mammalian embryogenesis, and stem cells. Here, worldwide experts in the S1P field describe in-depth techniques in an array of cell types and with various physiological applications, showcasing the important effects of S1P in developmentand in physiopathology. As a volume in the Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the relevant materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and timely, Sphingosine-1-Phosphate: Methods and Protocols, Second Edition is another key resource for scientists working in this fast-moving and dynamic field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 192 pp. Englisch.

Buch. Etat : Neu. Neuware -This volume provides broad coverage of computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those concerned with general techniques and concepts that apply to all organisms to others that are more specialized, covering specific biological systems such as viruses, Drosophila, and Homo sapiens. Written in the highly successful Methods in Molecular Biology series format, by authors who are active researchers in the field, many chapters include step-by-step procedures, which illustrate practical applications of the techniques described.Cutting-edge and thorough, Comparative Genomics: Methods and Protocols should be useful to students and researchers in the continually growing and exciting field of comparative genomics.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 496 pp. Englisch.

Buch. Etat : Neu. Neuware -This detailed volume explores numerous multidisciplinary approaches employed to analyze the role of different molecules or strategies used by different guests to survive inside hosts. Divided into several sections, the book delves into animal-pathogen interaction, microbe-microbe interaction, as well as plant-pathogen interaction. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 348 pp. Englisch.

Buch. Etat : Neu. Neuware -This detailed volume explores the latest methods that can be used to probe mRNA decay pathways and identify mRNA-binding protein targets as well as miRNA targets. Subjects include metabolic labelling and RNAseq methods for determining RNA decay rates, approaches for discovering RNA-binding protein targets, bioinformatics, miRNA targets and novel components of the miRNA-directed decay pathway, and recently developed approaches for studying nonsense-mediated mRNA decay, among other areas. Written for the highly popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 240 pp. Englisch.

Buch. Etat : Neu. Neuware -This detailed volume introduces the reader to current methods in glaucoma research, in particular those that make use of animal disease models. Given that the retinal ganglion cells damaged and destroyed by glaucoma do not regenerate after lowering the intraocular pressure, new therapeutic approaches that protect ganglion cells directly is a vital research goal that this volume¿s contents aim to aid scientists in developing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Buch. Etat : Neu. Neuware -This volume presents the latest developments and techniques used to study the physiopathology, diagnosis, and treatment of pre-eclampsia. Written for clinicians, obstetricians, basic scientists, researchers, and students the chapters in this book provide methods to study placental function using in vitro and ex vivo model systems, comprehensive genetic analysis of pre-eclampsia, identifying critical angiogenic factors associated with the development of pre-eclampsia, and controlled experiments that investigate potential therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, tips on troubleshooting and avoiding known pitfalls, as well as a description of the limitations and advantages of the described techniques.Cutting-edge and comprehensive, Pre-Eclampsia: Methods andProtocols is a valuable resource for anyone interested in learning more about the critical role of the placenta in the maternal-fetal relationship.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 372 pp. Englisch.

Buch. Etat : Neu. Neuware -This volume explores methods used to examine the structure-function relationship of glucose transporters both in vitro and ex vivo. Chapters in this book cover topics such as expression and purification of glucose transporters in heterologous expression systems, crystal structure determination, glucose transport activity assays in cellular and synthetic model systems, investigation of the GLUT4 membrane trafficking machinery by novel labeling strategies combined with advanced fluorescence microscopy methods, and tracking GLUT2 translocation by live cell imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 288 pp. Englisch.

Buch. Etat : Neu. Neuware -There are few clinical problems in the sleep medicine field that are more challenging than the sleep difficulties experienced by individuals suffering from post-traumatic stress disorder (PTSD). This book offers a unique, complete resource addressing all the basic concepts and clinical applications in sleep medicine in settings where combat-related PTSD is commonplace. Authored by leading international experts in the field of sleep/military medicine,Sleep and Combat-Related Post Traumatic Stress Disorder is organized in six sections and provides a broad perspective of the field, from the established theories to the most recent developments in research, including the latest neuroscientific perspectives surrounding sleep and PTSD. The result is a full assessment of sleep in relation to combat-related PTSD and a gold standard volume that is the first of its kind. This comprehensive title will be of great interest to a wide range of clinicians -- from academics and clinicians working within or in partnership with the military health care system to veteran hospital physicians and all health personnel who work with war veterans.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 440 pp. Englisch.

Buch. Etat : Neu. Neuware -The Handbook of East and Southeast Asian Archaeologyfocuses on the material culture and lifeways of the peoples of prehistoric and early historic East and Southeast Asia;their origins, behavior and identities as well as their biological, linguistic and cultural differences and commonalities. Emphasis is placed upon the interpretation of material culture to illuminate and explain social processes and relationships as well as behavior, technology, patterns and mechanisms of long-term change and chronology, in addition to the intellectual history of archaeology as a discipline in this diverse region. The Handbook augments archaeologically-focused chapters contributed by regional scholars by providing histories of research and intellectual traditions, and by maintaining a broadly comparative perspective. Archaeologically-derived data are emphasized with text-based documentary information, provided to complement interpretations of material culture. The Handbookis not restricted to art historical or purely descriptive perspectives; its geographical coverage includes the modern nation-states of China, Mongolia, Far Eastern Russia, North and South Korea, Japan, Taiwan, Vietnam, Cambodia, Laos, Thailand, Burma, Malaysia, Indonesia, the Philippines and East Timor.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 796 pp. Englisch.