Eroding matrix system lipid par dave vivek (2 résultats)

Taschenbuch. Etat : Neu. Self Eroding Matrix System | A Self Eroding Lipid Based Matrix for an Insoluble Drug | Vivek Dave (u. a.) | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639348088 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. …

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a self eroding matrix system made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.…