gene knockout protocols (41 résultats)

Hardcover. Etat : Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less 1.85.

Hardcover. Etat : Very Good. 8vo, hardcover. No dj. Vg+ condition. Prev. owner's name-labels removed from endpaper, contents bright, crisp & clean, unread. xi, 431 p., illus.

Etat : Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1550grams, ISBN:9781934115268.

Hardcover. Etat : Very Good. Methods in Molecular Biology, Volume 158. Shows how gene targeting techniques can be used to simulate human disease states. Includes techniques for embryo transplantation and in vitro ES cell differentiation. Written by hands- on experts who have optimized each method for experimental success. Offers step by step instructions and helpful notes on pitfalls to avoid. Professional book seller with storefront since 1975. All orders carefully packaged and promptly shipped.

Etat : Fair. Volume 530. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1350grams, ISBN:9781934115268.

Etat : New.

Etat : New. Satisfaction Guaranteed or your money back.

Etat : Hervorragend. Zustand: Hervorragend | Seiten: 431 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Etat : New. In.

Etat : New.

Etat : New. Editor(s): Tymms, M. J.; Kola, Ismail. Series: Methods in Molecular Biology. Num Pages: 431 pages, biography. BIC Classification: MFN. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 25. Weight in Grams: 714. . 2010. 1st ed. Softcover of orig. ed. 2001. Paperback. . . . .

Etat : New. Describes best techniques for the design of targeting constructs and for the analysis of the mouse phenotype. This title not only constitutes a source of reproducible techniques for those just entering the field of gene targeting, but also a key reference for genetic researchers. Editor(s): Tymms, M. J. Series: Methods in Molecular Biology. Num Pages: 431 pages, biography. BIC Classification: PSAK; PSD; TCBG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 229 x 152 x 28. Weight in Grams: 826. . 2001. Hardback. . . . .

Etat : New. Editor(s): Tymms, M. J.; Kola, Ismail. Series: Methods in Molecular Biology. Num Pages: 431 pages, biography. BIC Classification: MFN. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 25. Weight in Grams: 714. . 2010. 1st ed. Softcover of orig. ed. 2001. Paperback. . . . . Books ship from the US and Ireland.

Etat : New. Describes best techniques for the design of targeting constructs and for the analysis of the mouse phenotype. This title not only constitutes a source of reproducible techniques for those just entering the field of gene targeting, but also a key reference for genetic researchers. Editor(s): Tymms, M. J. Series: Methods in Molecular Biology. Num Pages: 431 pages, biography. BIC Classification: PSAK; PSD; TCBG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 229 x 152 x 28. Weight in Grams: 826. . 2001. Hardback. . . . . Books ship from the US and Ireland.

Gebunden. Etat : New. Includes supplementary material: sn.pub/extrasAs the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biologic.

Etat : New. In.

Etat : Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.

Etat : As New. Unread book in perfect condition.

Paperback. Etat : Like New. Like New. book.

Hardcover. Etat : Like New. Like New. book.

Etat : As New. Unread book in perfect condition.

Buch. Etat : Neu. Neuware - As the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biological functions of these genes, and how alterations lead to disease states. In this task there is a severe limitation in working with human material, but the mouse has been adopted as the favored animal model because of the available genetic resources and the highly conserved gene conservation linkage organization. In just of ten years since the first gene-targeting experiments were p- formed in embryonic stem (ES) cells and mutations transmitted through the mouse germline, more than a thousand mouse strains have been created. These achievements have been made possible by pioneering work that showed that ES cells derived from preimplantation mouse embryos could be cultured for prolonged periods without differentiation in culture, and that homologous rec- bination between targeting constructs and endogenous DNA occurred at a f- quency sufficient for recombinants to be isolated. In the next few years the mouse genome will be systematically altered, and the techniques for achi- ing manipulations are constantly being streamlined and improved.

Taschenbuch. Etat : Neu. Gene Knockout Protocols | Wolfgang Wurst (u. a.) | Taschenbuch | xvi | Englisch | 2014 | Humana | EAN 9781627038348 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Buch. Etat : Neu. Neuware -Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network. The mouse offers many advantages for the use of genetics to study human biology and disease, unmatched among other m- mals. Its development, body plan, physiology, behavior, and diseases have much in common, based on the fact that 99% of the human genes have a mouse ortholog. The investigation of gene function using mouse models is based on many years of tech- logical development. In the two decades since gene targeting in murine embryonic stem (ES) cells was first described by Mario Capecchi and colleagues, more than 3000 predesigned mouse mutants have been developed. To date, a variety of mouse mutagenesis techniques, either gene- or phenotype-driven, are used as systematic approaches. The availability of the genome sequence supports gene-driven approaches such as gene-trap and targeted mutagenesis in ES cells, allowing efficient and precise gene disruption. In combination with the use of site-specific DNA recombinases, in particular the Cre/loxP system, gene disruptioncan be directed to specific cell types in conditionalmousemutants. Furthermore,chemicalandtransposonmutagenesisofthe mouse genome enables us to perform phenotype-driven screens for the unbiased identification of phenotype¿genotype correlations involved in models of human d- ease. Over the next several years, the mouse genome will be systematically altered, and the techniques for achieving predesigned manipulations will be constantly developed further and improved. The second edition of Gene Knockout Protocols brings together distinguished c-tributorswithextensiveexperienceinthegenetargetingandmousegenetics fields.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 540 pp. Englisch.

Paperback. Etat : Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biological functions of these genes, and how alterations lead to disease states. In this task there is a severe limitation in working with human material, but the mouse has been adopted as the favored animal model because of the available genetic resources and the highly conserved gene conservation linkage organization. In just of ten years since the first gene-targeting experiments were p- formed in embryonic stem (ES) cells and mutations transmitted through the mouse germline, more than a thousand mouse strains have been created. These achievements have been made possible by pioneering work that showed that ES cells derived from preimplantation mouse embryos could be cultured for prolonged periods without differentiation in culture, and that homologous rec- bination between targeting constructs and endogenous DNA occurred at a f- quency sufficient for recombinants to be isolated. In the next few years the mouse genome will be systematically altered, and the techniques for achi- ing manipulations are constantly being streamlined and improved. 444 pp. Englisch.

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes supplementary material: sn.pub/extrasAs the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biologic.

Etat : new. Questo è un articolo print on demand.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -As the major task of sequencing the human genome is near completion and full complement of human genes are catalogued, attention will be focused on the ultimate goal: to understand the normal biological functions of these genes, and how alterations lead to disease states. In this task there is a severe limitation in working with human material, but the mouse has been adopted as the favored animal model because of the available genetic resources and the highly conserved gene conservation linkage organization. In just of ten years since the first gene-targeting experiments were p- formed in embryonic stem (ES) cells and mutations transmitted through the mouse germline, more than a thousand mouse strains have been created. These achievements have been made possible by pioneering work that showed that ES cells derived from preimplantation mouse embryos could be cultured for prolonged periods without differentiation in culture, and that homologous rec- bination between targeting constructs and endogenous DNA occurred at a f- quency sufficient for recombinants to be isolated. In the next few years the mouse genome will be systematically altered, and the techniques for achi- ing manipulations are constantly being streamlined and improved.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 444 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network. The mouse offers many advantages for the use of genetics to study human biology and disease, unmatched among other m- mals. Its development, body plan, physiology, behavior, and diseases have much in common, based on the fact that 99% of the human genes have a mouse ortholog. The investigation of gene function using mouse models is based on many years of tech- logical development. In the two decades since gene targeting in murine embryonic stem (ES) cells was first described by Mario Capecchi and colleagues, more than 3000 predesigned mouse mutants have been developed. To date, a variety of mouse mutagenesis techniques, either gene- or phenotype-driven, are used as systematic approaches. The availability of the genome sequence supports gene-driven approaches such as gene-trap and targeted mutagenesis in ES cells, allowing efficient and precise gene disruption. In combination with the use of site-specific DNA recombinases, in particular the Cre/loxP system, gene disruptioncan be directed to specific cell types in conditionalmousemutants. Furthermore,chemicalandtransposonmutagenesisofthe mouse genome enables us to perform phenotype-driven screens for the unbiased identification of phenotype-genotype correlations involved in models of human d- ease. Over the next several years, the mouse genome will be systematically altered, and the techniques for achieving predesigned manipulations will be constantly developed further and improved. The second edition of Gene Knockout Protocols brings together distinguished c- tributorswithextensiveexperienceinthegenetargetingandmousegenetic sfields. 540 pp. Englisch.