Next generation sequencing (701 résultats)

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Paperback or Softback. Etat : New. Speed and Efficiency: Demystifying Next-Generation Sequencing Technology. Book.

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hardcover. Etat : Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority.

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xiii, 355 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch.

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The analysis of next-generation sequencing (NGS) data is a major topic in bioinfor-matics: short reads obtained from DNA, the molecule encoding the genome of livingorganisms, are processed to provide insight into biological or medical questions. Thisthesis provides novel solutions to major topics within the analysis of NGS data, focusingon parallelization, scalability and reproducibility.The read mapping problem is to find the origin of the short reads within a given referencegenome. We contribute the q-group index, a novel data structure for read mapping withparticularly small memory footprint. The q-group index comes with massively parallelbuild and query algorithms targeted towards modern graphics processing units (GPUs).On top, the read mapping software PEANUT is presented, which outperforms state ofthe art read mappers in speed while maintaining their accuracy.The variant calling problem is to infer (i.e., call) genetic variants of individuals comparedto a reference genome using mapped reads. It is usually solved in a Bayesian way. In this work, we show how to integrate filtering of variants into the calling with analgebraic approach and provide an intuitive solution for controlling the false discoveryrate along with solving other challenges of variant calling like scaling with a growingset of biological samples.Depending on the research question, the analysis of NGS data entails many other steps,typically involving diverse tools, data transformations and aggregation of results. Thesesteps can be orchestrated by workflow management. We present the general purposeworkflow system Snakemake, which provides an easy to read domain-specific languagefor defining and documenting workflows. Snakemake provides an execution environmentthat allows to scale a workflow to available resources, including parallelization acrossCPU cores or cluster nodes, restricting memory usage or the number of availablecoprocessors like GPUs.…

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xviii, 493 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch.

Etat : New. In English.

Softcover. 129 S. Guter Zustand. Die Leseseiten sind sauber und ohne Markierungen. Leichte Lager- und Gebrauchsspuren. Einband leicht fleckig. Buchecken leicht bestoßen. Ansonsten ordentliches Exemplar. 9783844001556 Altersfreigabe FSK ab 0 Jahre Sprache: Deutsch Gewicht in Gramm: 789.

PF. Etat : New.

Etat : New.

Etat : New. pp. 462.

Etat : New. pp. 462.