Nmda receptors (65 résultats)

Etat : New.

Taschenbuch. Etat : Neu. In-Silico Screening of Potent Anticonvulsant Agents | Discovery of Potent Anticonvulsant Ligands as Dual NMDA and AMPA Receptors Antagonists | Kamlendra S. Bhadoriya (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783659137266 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

hardcover. Etat : Very Good. No dust jacket as issued. No dust jacket. Very Good hardcover with light shelfwear - NICE! Standard-sized.

Taschenbuch. Etat : Neu. Role of glutamatergic receptors in brain development | NMDA-type ionotropic and group II metabotropic glutamatergic receptors in cerebral cortical development | Vivian Oliveira Sousa Corrêa | Taschenbuch | Englisch | 2025 | Our Knowledge Publishing | EAN 9786208478490 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Etat : New.

Etat : As New. Unread book in perfect condition.

Etat : New.

Etat : New. In English.

Etat : As New. Unread book in perfect condition.

Etat : New.

Taschenbuch. Etat : Neu. NMDA Receptors | Methods and Protocols | Nail Burnashev (u. a.) | Taschenbuch | Methods in Molecular Biology | xiii | Englisch | 2018 | Springer | EAN 9781493984527 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Etat : Neu. The NMDA Receptors | Kenji Hashimoto | Taschenbuch | The Receptors | x | Englisch | 2018 | Palgrave Macmillan | EAN 9783319842431 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores the latest techniques used by researchers to help them better understand the NMDAR structure-function relations, principles, and rules that govern how NMDARs operate in brain processing. The volume includes a detailed introductory chapter describing the field and is divided into three parts. Topics covered in the volume include: quantification of NMDAR subunit genes expression by qRT-PCR; detection of NMDARs antibodies in encephalitis; recombinant channels in host cells using a fast agonist application system; GluNs detection and functions in microglial cells; and NMDARs as voltage sensors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, NMDA Receptors: Methods and Protocols is a valuable resource that discusses the diversity of the currently-used methods, the importance of NMDARs and their complexity, and the progress that has already been made. This book will be of interest to scientists, clinicians, and industry professionals working in this field.…

Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume provides a history of and an update on the functional status of the NMDA receptors. The NMDA receptors are essential for neuronal development, synaptic plasticity, learning, and cell survival. It covers molecular, cellular, anatomical, biochemical, and behavioral aspects, to highlight their distinctive regulatory properties, their functional significance, and their therapeutic potential in a number of diseases. A group of international experts discuss the development of NMDA receptors, their basic functions, and how they are implicated in a wide range of diseases including depression, psychosis, and pain. …

Taschenbuch. Etat : Neu. NMDA Receptors | Methods and Protocols | Nail Burnashev (u. a.) | Taschenbuch | Methods in Molecular Biology | xiii | Englisch | 2025 | Humana | EAN 9781071638323 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Etat : New. pp. 148.

Etat : New. pp. 148.

Etat : New. Softcover reprint of the original 1st ed. 2017 edition NO-PA16APR2015-KAP.

Etat : New. pp. 320.

Hardcover. Etat : Brand New. 1st edition. 314 pages. 10.00x7.25x1.00 inches. In Stock.

Etat : Hervorragend. Zustand: Hervorragend | Seiten: 305 | Sprache: Englisch | Produktart: Bücher | This fully updated volume explores N-Methyl-D-aspartate receptors (NMDARs), and the structure-function relations, principles, and rules that govern how NMDARs operate in brain processing under normal and pathological conditions. With chapters from leading laboratories around the world, this book examines the expression and purification of diverse NMDA receptor subtypes, gene targeting and generation of conditional NMDAR mutant mouse lines, studies of NMDARs in zebrafish, electrophysiological studies, NMDARs modeling in silico, drug development with artificial intelligence, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, NMDA Receptors: Methods and Protocols, SecondEdition serves as an ideal guide to the diversity of possible approaches in the field of NMDARs and the progress that has been made in recent years.…

Etat : New.

Paperback. Etat : Brand New. reprint edition. 148 pages. 9.25x6.10x0.37 inches. In Stock.

Etat : Sehr gut. Zustand: Sehr gut | Seiten: 305 | Sprache: Englisch | Produktart: Bücher | This fully updated volume explores N-Methyl-D-aspartate receptors (NMDARs), and the structure-function relations, principles, and rules that govern how NMDARs operate in brain processing under normal and pathological conditions. With chapters from leading laboratories around the world, this book examines the expression and purification of diverse NMDA receptor subtypes, gene targeting and generation of conditional NMDAR mutant mouse lines, studies of NMDARs in zebrafish, electrophysiological studies, NMDARs modeling in silico, drug development with artificial intelligence, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, NMDA Receptors: Methods and Protocols, SecondEdition serves as an ideal guide to the diversity of possible approaches in the field of NMDARs and the progress that has been made in recent years.…

Etat : New. 2nd ed. 2024 edition NO-PA16APR2015-KAP.

Hardcover. Etat : gut. 2024. NMDA Receptors: Methods and Protocols (Methods in Molecular Biology, 2799, Band 2799) In englischer Sprache. pages.

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Epilepsy is a disorder of the central nervous system characterized by paroxysmal, excessive, hyper-synchronous discharges of large numbers of neurons. To identify novel and potent anticonvulsant ligands, initially 2D-QSAR,3D-QSAR and pharmacophore models were generated using a series some prop-2-eneamido and 1-acetyl-pyrazolin derivatives of aminobenzothiazole as anticonvulsants. To discover new hits, developed pharmacophore model was subjected to screen molecules from specs database. Screened hits which were showing good predicting activities according to both 2D and 3DQSAR models were subjected to docking screening. Gly/NMDA and AMPA receptors are effective and validated anti-convulsant targets and used to report the binding affinity of screened hit on Gly/NMDA, AMPA receptors. A representative set of 14 compounds with effective biological activity and good binding affinity on both NMDA and AMPA receptors were screen out which may potential lead for anticonvulsant activity. …

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Neuroglial interactions play a key role in the development of the nervous system. This study investigated the role of synaptic transmitters (glutamate and D-serine) and a trophic factor, transforming growth factor-beta1 (TGF-beta1), as mediators of these interactions during the differentiation of radial glial cells (neural progenitors) and astrocytes. Our data suggest a possible role for NMDA-type glutamatergic receptors in GR specialization during neuronal migration in the cerebral cortex. We also analyzed the role of glutamate in astrocytic maturation through TGF-beta1 pathways. The activation of metabotropic glutamate receptors 2/3 by neurons induces the secretion of TGF-beta1, leading to the activation of the GFAP gene and astrocyte maturation. Both the production of TGF-beta1 and the activation of the GFAP gene by this factor involve the MAPK/PI3K pathways. Our work shows that glutamatergic receptors are involved in events of cerebral cortex development such as GR specification and astrocyte maturation.…

Etat : new. Questo è un articolo print on demand.

Etat : new. Questo è un articolo print on demand.