structure function analysis protein coupled receptors (9 résultats)

Hardcover. Etat : New.

Hardcover. Etat : new. Hardcover. G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity. This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and biophysical) which have been used successfully in studying the structure and function of GPCRs. With contributions from international leaders in the field, the editor provides overviews of various techniques, followed by in-depth descriptions of basic procedures and discussions of critical experimental parameters. Divided into specific, accessible sections, Structure-Function Analysis of G Protein-Coupled Receptors includes: * An overview of mutagenesis techniques * Examples of molecular modeling techniques * Using peptides as tools for the study of GPCR interactions * Site-Directed Spin Labeling (SDSL) studies of the GPCR rhodopsin * A complete description of the electron-crystalographic analysis of two-dimensional rhodopsin crystals * The use of nuclear magnetic resonance techniques to study GPCR structure This presentation of methods (including molecular genetic, biochemical, and biophysical) is useful for studying the structure and function of G protein-coupled receptors (GPCRs). It focuses on methodology, but also includes techniques that can be used by readers at the laboratory bench. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Etat : new. Hardcover. G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity. This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and biophysical) which have been used successfully in studying the structure and function of GPCRs. With contributions from international leaders in the field, the editor provides overviews of various techniques, followed by in-depth descriptions of basic procedures and discussions of critical experimental parameters. Divided into specific, accessible sections, Structure-Function Analysis of G Protein-Coupled Receptors includes: * An overview of mutagenesis techniques * Examples of molecular modeling techniques * Using peptides as tools for the study of GPCR interactions * Site-Directed Spin Labeling (SDSL) studies of the GPCR rhodopsin * A complete description of the electron-crystalographic analysis of two-dimensional rhodopsin crystals * The use of nuclear magnetic resonance techniques to study GPCR structure This presentation of methods (including molecular genetic, biochemical, and biophysical) is useful for studying the structure and function of G protein-coupled receptors (GPCRs). It focuses on methodology, but also includes techniques that can be used by readers at the laboratory bench. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Gebunden. Etat : New. Structure-Function Analysis of G Protein-Coupled Receptors edited by Juergen Wess.G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, playing key roles in a remarkably large number of physiological and pathophysiological.

Etat : New. G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Editor(s): Wess, Jurgen. Series: Receptor Biochemistry & Methodology. Num Pages: 432 pages, Illustrations (some col.). BIC Classification: PHVN; PSBC; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 179 x 31. Weight in Grams: 932. . 1999. 1st Edition. Hardcover. . . . .

Hardcover. Etat : Brand New. 1st edition. 412 pages. 10.50x7.50x1.00 inches. In Stock.

Buch. Etat : Neu. Neuware - Über 40 Prozent der gegenwärtig von Pharmakonzernen untersuchten pharmakologischen Targets stehen im Zusammenhang mit G-Protein-gekoppelten Rezeptoren (GPCRs). Bei der Untersuchung von Struktur, Eigenschaften und Funktion der GPCRs hilft dieser Band, der die aktuellsten molekulargenetischen, biochemischen und biophysikalischen Methoden zusammenfaßt. Die erfahrenen Autoren bewerten jedes vorgestellte Verfahren im Hinblick auf verschiedene Anwendungen. (08/99).

Etat : New. G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Editor(s): Wess, Jurgen. Series: Receptor Biochemistry & Methodology. Num Pages: 432 pages, Illustrations (some col.). BIC Classification: PHVN; PSBC; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 179 x 31. Weight in Grams: 932. . 1999. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.

Hardcover. Etat : new. Hardcover. G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity. This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and biophysical) which have been used successfully in studying the structure and function of GPCRs. With contributions from international leaders in the field, the editor provides overviews of various techniques, followed by in-depth descriptions of basic procedures and discussions of critical experimental parameters. Divided into specific, accessible sections, Structure-Function Analysis of G Protein-Coupled Receptors includes: * An overview of mutagenesis techniques * Examples of molecular modeling techniques * Using peptides as tools for the study of GPCR interactions * Site-Directed Spin Labeling (SDSL) studies of the GPCR rhodopsin * A complete description of the electron-crystalographic analysis of two-dimensional rhodopsin crystals * The use of nuclear magnetic resonance techniques to study GPCR structure This presentation of methods (including molecular genetic, biochemical, and biophysical) is useful for studying the structure and function of G protein-coupled receptors (GPCRs). It focuses on methodology, but also includes techniques that can be used by readers at the laboratory bench. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.