Gessner p (74 résultats)

Paperback. Etat : Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less. Kristi Dranginis (illustrateur).

Paperback. Etat : Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less. Kristi Dranginis (illustrateur).

Paperback. Etat : Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less. Kristi Dranginis (illustrateur).

Etat : Good. shelf wear, paperback Used - Good 2012 1st Edition All purchases support Project HOME - ending homelessness in Philadelphia. Kristi Dranginis (illustrateur).

Paperback. Etat : Good. Connecting readers with great books since 1972! Used books may not include companion materials, and may have some shelf wear or limited writing. We ship orders daily and Customer Service is our top priority. Kristi Dranginis (illustrateur).

Etat : very_good. Used with minimal wear, no writing or markings, corners maybe bent, few crease lines. Kristi Dranginis (illustrateur).

paperback. Etat : Good. This is a used book in good condition and may show some signs of use or wear . This is a used book in good condition and may show some signs of use or wear .

Paperback. Etat : Brand New. 1st edition. 107 pages. 8.40x5.40x0.40 inches. In Stock. Kristi Dranginis (illustrateur).

Etat : Gut. 204 S. Mit leichten Gebrauchsspuren. Guter Zustand Bibl-Ex. Papier alterungsbedingt vergilbt. Stempel auf Seitenschnitt. Sprache: Deutsch Gewicht in Gramm: 811 Paperback/ broschiert broschiert/ Taschenbuch.

126 S., HC mit SU, 4°, SU gering randlädiert, sonst sehr gut erhalten Sprach: deu 1111.

Broschiert. Etat : Gut. 68 S., graph. Darst. Überschußkraft und Gewinnbeteiligung in der Lebensversicherung. Professor Dr. P. Gessner.[Schriftenreihe Angewandte Versicherungsmathematik, Heft 7], [Deutsche Gesellschaft für Versicherungsmathematik]. Guter Gesamtzustand. Sprache: Deutsch Gewicht in Gramm: 101.…

Etat : New.

Paperback. Etat : New. This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds. Recent findings regarding the ability of diethyldithiocarbamate (ditiocarb, Imuthiol®) to delay the progression of HN infections and AIDS, the discovery of its potential as a rescue agent in cancer chemotherapy, and the identification of disulfiram (Antabuse®) regimens that allow alcoholics to achieve abstinence of many months' duration have made writing this book an exciting experience. At the same time the fact that the two drugs differ substantially in their pharmacological effects in spite of their easy interconvertibility has rendered the writing intellec­ tually challenging. Diethyldithiocarbamate, an agent seemingly less toxic than aspirin, rivals it in the multiplicity and diversity of its pharmacological proper­ ties. Notable among these are the manyfold potent immunostimulant effects, and though most of these involve effects on T -cells, the mechanism of diethyldithiocarbamate's action remains far from clear. The drug is also a potent chelator of heavy metals and this has led to a number of clinical applications. As might be expected, it inhibits several important enzymes. Further, it is one of the most effective radioprotective agents; it also protects organisms against a variety of toxic agents. Softcover reprint of the original 1st ed. 1992. …

Etat : New.

Etat : New. pp. 476 Index.

Paperback. Etat : Brand New. 476 pages. 9.21x6.14x0.96 inches. In Stock.

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds. Recent findings regarding the ability of diethyldithiocarbamate (ditiocarb, Imuthiol®) to delay the progression of HN infections and AIDS, the discovery of its potential as a rescue agent in cancer chemotherapy, and the identification of disulfiram (Antabuse®) regimens that allow alcoholics to achieve abstinence of many months' duration have made writing this book an exciting experience. At the same time the fact that the two drugs differ substantially in their pharmacological effects in spite of their easy interconvertibility has rendered the writing intellec tually challenging. Diethyldithiocarbamate, an agent seemingly less toxic than aspirin, rivals it in the multiplicity and diversity of its pharmacological proper ties. Notable among these are the manyfold potent immunostimulant effects, and though most of these involve effects on T -cells, the mechanism of diethyldithiocarbamate's action remains far from clear. The drug is also a potent chelator of heavy metals and this has led to a number of clinical applications. As might be expected, it inhibits several important enzymes. Further, it is one of the most effective radioprotective agents; it also protects organisms against a variety of toxic agents.…

Taschenbuch. Etat : Neu. Disulfiram and its Metabolite, Diethyldithiocarbamate | Pharmacology and status in the treatment of alcoholism, HIV infections, AIDS and heavy metal toxicity | P. K. Gessner | Taschenbuch | xix | Englisch | 2012 | Springer | EAN 9789401050289 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Hardback. Etat : New. The widely-used drug disulfiram metabolizes rapidly to form diethyldithiocarbamate, and it is impossible to study its metabolic rate inhibitory action on acetaldehyde metabolism without considering the properties of the metabolite, even though they have different spectra of pharmacological activity and different applications. Diethyldithiocarbamate is pharmacologically active in a greater number of ways than had been originally suggested. Its uses have ranged from an antidote to nickel carbonyl intoxication to the balancing of mossy fibre botons in the hypothalamus, and from its application as a rescue agent in cancer chemotherapy to its recently confirmed ability to inhibit the progression of HIV infections. There is sustained interest in its ability to chelate heavy metals, particularly cadmium, thallium and nickel, and whilst it continues to be used experimentally in cisplatin chemotherapy for protection against renal toxicity, there is now increasing interest in its ability to counteract bone marrow toxicity of a range of chemotherapeutic agents.There has been a recent increase in the use of disulfiram in the treatment of alcoholism, it having been credited with affecting a marked decrease in the incidence of cases requiring treatment for this condition. The growing level of research and clinical interest in disulfiram and diethyldithiocarbamate has resulted in a need for an integrated synthesis of current knowledge on the subject. This book provides a critical review of the current status of research in the properties, pharmacology and toxicology of disulfiram and diethyldithiocarbamate and their use for the treatment of a variety of human disease conditions, including AIDS, cancer, alcoholism and heavy metal intoxication. The text is supported by a bibliography and the book should serve as an important reference source for pharmacologists, biomedical scientists, immunologists, biochemists and clinicians.…

Etat : New. pp. 472 1st Edition.

Paperback. Etat : New. This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds. Recent findings regarding the ability of diethyldithiocarbamate (ditiocarb, Imuthiol®) to delay the progression of HN infections and AIDS, the discovery of its potential as a rescue agent in cancer chemotherapy, and the identification of disulfiram (Antabuse®) regimens that allow alcoholics to achieve abstinence of many months' duration have made writing this book an exciting experience. At the same time the fact that the two drugs differ substantially in their pharmacological effects in spite of their easy interconvertibility has rendered the writing intellec­ tually challenging. Diethyldithiocarbamate, an agent seemingly less toxic than aspirin, rivals it in the multiplicity and diversity of its pharmacological proper­ ties. Notable among these are the manyfold potent immunostimulant effects, and though most of these involve effects on T -cells, the mechanism of diethyldithiocarbamate's action remains far from clear. The drug is also a potent chelator of heavy metals and this has led to a number of clinical applications. As might be expected, it inhibits several important enzymes. Further, it is one of the most effective radioprotective agents; it also protects organisms against a variety of toxic agents. Softcover reprint of the original 1st ed. 1992. …

Etat : New. pp. 472.

Gebunden. Etat : New.

Etat : As New. Unread book in perfect condition.

Buch. Etat : Neu. Neuware - Introduction and scope of monograph. Relevant chemical and physical properties. Reactions of disulfiram and diethyldithiocarbamate with blood constituents. Assay methods for disulfiram and metabolites in biological materials. Metabolism of disulfiram and diethyldithiocarbamate. Pharmacokinetic aspects of the disposition of disulfiram and metabolites. Heavy metals: effects of diethyldithiocarbamate and disulfiram administration. Disulfiram and diethyldithiocarbamate as enzyme inhibitors. Inhibition of aldehyde dehydrogenase. The disulfiram-ethanol reaction. Disulfiram therapy of alcohol abuse. Various biological phenomena. Immunomodulatory actions of diethyldithiocarbamate. Clinical status of diethyldithiocarbamate as an immunostimulant. Modulation of various biological phenomena. Modulation of cancer chemotherapy. Toxicology. Bibliography. Index.…

Paperback. Etat : Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Etat : As New. Unread book in perfect condition.

Hardback. Etat : New. The widely-used drug disulfiram metabolizes rapidly to form diethyldithiocarbamate, and it is impossible to study its metabolic rate inhibitory action on acetaldehyde metabolism without considering the properties of the metabolite, even though they have different spectra of pharmacological activity and different applications. Diethyldithiocarbamate is pharmacologically active in a greater number of ways than had been originally suggested. Its uses have ranged from an antidote to nickel carbonyl intoxication to the balancing of mossy fibre botons in the hypothalamus, and from its application as a rescue agent in cancer chemotherapy to its recently confirmed ability to inhibit the progression of HIV infections. There is sustained interest in its ability to chelate heavy metals, particularly cadmium, thallium and nickel, and whilst it continues to be used experimentally in cisplatin chemotherapy for protection against renal toxicity, there is now increasing interest in its ability to counteract bone marrow toxicity of a range of chemotherapeutic agents.There has been a recent increase in the use of disulfiram in the treatment of alcoholism, it having been credited with affecting a marked decrease in the incidence of cases requiring treatment for this condition. The growing level of research and clinical interest in disulfiram and diethyldithiocarbamate has resulted in a need for an integrated synthesis of current knowledge on the subject. This book provides a critical review of the current status of research in the properties, pharmacology and toxicology of disulfiram and diethyldithiocarbamate and their use for the treatment of a variety of human disease conditions, including AIDS, cancer, alcoholism and heavy metal intoxication. The text is supported by a bibliography and the book should serve as an important reference source for pharmacologists, biomedical scientists, immunologists, biochemists and clinicians.…

Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Etat : New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.