Harold gainer (27 résultats)

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Etat : New. Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. Series: Wiley-INF Masterclass in Neuroendocrinology Series. Num Pages: 488 pages. BIC Classification: MFN; MJG; MJN. Category: (P) Professional & Vocational. Dimension: 179 x 251 x 26. Weight in Grams: 1066. . 2016. Hardback. . . . . …

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Etat : New. Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. Series: Wiley-INF Masterclass in Neuroendocrinology Series. Num Pages: 488 pages. BIC Classification: MFN; MJG; MJN. Category: (P) Professional & Vocational. Dimension: 179 x 251 x 26. Weight in Grams: 1066. . 2016. Hardback. . . . . Books ship from the US and Ireland. …

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Buch. Etat : Neu. Neuware - Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today's neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. ¿Written by a team of internationally renowned researchers¿Both print and enhanced Elektronisches Buch versions are available¿Illustrated in full colour throughout This is the third volume in a new Series 'Masterclass in Neuroendocrinology' , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA.…

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Elucidation of the important roles played by peptides as hypothalamic-adenohypo physeal releasing factors, or regulatory hormones, has in recent years led to the recognition that peptides may also be of significance as intercellular messengers in other regions of the nervous system. In this regard, it is interesting that Sub stance P, which has been proposed as a putative neurotransmitter in the spinal cord, was rediscovered by Leeman and her co-workers during their search for the corticotropin-releasing factor in the hypothalamus. Indeed, with the wide spread availability and use of radioimmunoassay techniques, it has become ap parent that various 'hypothalamic releasing factors' are localized in extrahypo thalamic areas of the central nervous system as well. This book represents an expression of the belief that the impact on neurobiology of research into neuro peptides will be comparable to, if not greater than, the recent achievements obtained with the biogenic amines. As already appears to be the case, future inves tigations on brain pep tides will undoubtedly uncover a host of new transmitter candidates, with obvious implications for neuropharmacology. Perhaps the most dramatic developments in this field have been the discoveries of the endogenous opiate peptides (enkephalin and endorphin), and the profound physiological and behavioral effects of specific peptides. 488 pp. Englisch.…

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. 1 Peptides in Neurobiology: Historical Introduction.- 1. The Neurosecretory Neuron and the Concept of Neurosecretion.- 2. The Hypothalamic Origin of the Posterior Lobe Hormones.- 3. The Hypothalamic Control of the Adenohypophysis.- 4. Nonhormonal Neurosecre.…

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Elucidation of the important roles played by peptides as hypothalamic-adenohypo physeal releasing factors, or regulatory hormones, has in recent years led to the recognition that peptides may also be of significance as intercellular messengers in other regions of the nervous system. In this regard, it is interesting that Sub stance P, which has been proposed as a putative neurotransmitter in the spinal cord, was rediscovered by Leeman and her co-workers during their search for the corticotropin-releasing factor in the hypothalamus. Indeed, with the wide spread availability and use of radioimmunoassay techniques, it has become ap parent that various 'hypothalamic releasing factors' are localized in extrahypo thalamic areas of the central nervous system as well. This book represents an expression of the belief that the impact on neurobiology of research into neuro peptides will be comparable to, if not greater than, the recent achievements obtained with the biogenic amines. As already appears to be the case, future inves tigations on brain pep tides will undoubtedly uncover a host of new transmitter candidates, with obvious implications for neuropharmacology. Perhaps the most dramatic developments in this field have been the discoveries of the endogenous opiate peptides (enkephalin and endorphin), and the profound physiological and behavioral effects of specific peptides.…

Etat : New. Print on Demand pp. 488 49:B&W 6.14 x 9.21 in or 234 x 156 mm (Royal 8vo) Perfect Bound on White w/Gloss Lam.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -1 Peptides in Neurobiology: Historical Introduction.- 1. The Neurosecretory Neuron and the Concept of Neurosecretion.- 2. The Hypothalamic Origin of the Posterior Lobe Hormones.- 3. The Hypothalamic Control of the Adenohypophysis.- 4. Nonhormonal Neurosecretory Signals to Endocrine and Nonendocrine Effector Cells.- 5. Peptidergic Interneuronal Communication.- 6. Conclusion.- 7. References.- 2 Application of Fluorescent Techniques to the Study of Peptides.- 1. Introduction.- 2. Preparation of Materials and Equipment.- 3. Isolation of Peptides from Tissues.- 4. Separation and Detection of Peptides.- 5. Applications.- 6. Conclusion.- 7. References.- 3 Specific Problems in the Identification and Quantitation of Neuropeptides by Radioimmunoassay.- 1. Introduction.- 2. Radioimmunoassay for Detection of Well-Characterized Peptides in Nervous Tissues.- 3. Development of Radioimmunoassay Systems for Newly Described Peptides.- 4. Conclusions and Conjectures.- 5. References.- 4 Immunocytochemistry of Neuropeptides and Their Receptors.- 1. Introduction.- 2. The Unlabeled Antibody Enzyme Method-Sensitivity of Immunocytochemistry.- 3. Modifications of the Unlabeled Antibody Enzyme Method.- 4. Immunocytochemical Staining of Nervous Tissue.- 5. Neurotransmitter Pathways-Catecholamines and Serotonin.- 6. Hypothalamopituitary Pathways.- 7. Neuropeptide Receptors.- 8. Nonpituitary Neurosecretory Peptide Pathways.- 9. References.- 5 Substance P and Neurotensin.- 1. Introduction.- 2. Guidelines for the Isolation of Biologically Active Peptides.- 3. Guidelines for the Radioimmunoassay of Small Peptides.- 4. Substance P.- 5. Neurotensin.- 6. References.- 6 Biologically Active Peptides in the Mammalian Central Nervous System.- 1. Introduction.- 2. Historical Perspective.- 3. IndirectMethods for Locating Neurosecretory Cells.- 4. Regional Distribution of Selected Peptides.- 5. Conclusion.- 6. References.- 7 Peptides Containing Probable Transmitter Candidates in the Central Nervous System.- 1. General Properties of CNS Peptides.- 2. Peptide and Peptidoamine Synthesis with N-Terminal Acetyl-Asp.- 3. Factors That Affect the Levels and Release of Peptides in the CNS.- 4. A Working Hypothesis of Peptides as the Final Common Pathway of Multisignal Integration.- 5. Specific Examples of the Working Hypothesis.- 6. Conclusion.- 7. References.- 8 Biosynthesis of Neuronal Peptides.- 1. Introduction.- 2. The Precursor-Protein (Prohormone) Concept.- 3. Strategy for the Study of Peptide Biosynthesis in Neurons.- 4. Peptidergic Neurons in Aplysia as Model Systems.- 5. Biosynthesis of Neurohypophyseal Peptides and Neurophysin.- 6. Regulation of Neuronal Peptide Biosynthesis.- 7. Biological Significance of the Precursor Mode of Peptide Biosynthesis.- 8. Conclusion.- 9. References.- 9 Conversion and Inactivation of Neuropeptides.- 1. Introduction.- 2. Conversion of Prohormones.- 3. Inactivation of Active Peptides.- 4. References.- 10 Peptides in Invertebrate Nervous Systems.- 1. Introduction.- 2. Coelenterata.- 3. Arthropoda (Crustacea).- 4. Arthropoda (Insecta).- 5. Mollusca.- 6. Echinodermata: Radial Nerve Factor.- 7. Conclusion.- 8. References.- 11 Physiological Roles of Peptides in the Nervous System.- 1. Introduction.- 2. Substance P.- 3. Angiotensin II.- 4. Parvicellular Peptides: Thyrotropin-Releasing Hormone and Luteinizing Hormone-Releasing Hormone.- 5. Magnocellular Peptides: Antidiuretic Hormone (Lysine Vasopressin) and Oxytocin.- 6. Conclusions.- 7. References.- 12 Electrical Activity of Neurosecretory Terminals and Control of Peptide Hormone Release.-1. Introduction.- 2. The Crustacean X-Organ Sinus Gland Neurosecretory System.- 3. General Conclusions.- 4. References.- 13 Endogenous Opiate Peptides.- 1. Introduction.- 2. The Opiate Receptor.- 3. Adenylate Cyclase and the Mechanism of Addiction.- 4. Endogenous Opiates.- 5. Physiological Role of Endogenous Opiate Peptides.- 6. References.- 7. A.…

Etat : New. PRINT ON DEMAND pp. 488.