Muntean daniela lucia (38 résultats)

PAP. Etat : New. New Book. Shipped from UK. Established seller since 2000.

PAP. Etat : New. New Book. Shipped from UK. Established seller since 2000.

Etat : New.

Etat : New.

Etat : New.

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Taschenbuch. Etat : Neu. Neuware -Wirtualne przesiewanie odnosi si¿ do szeregu technik 'in silico' stosowanych do przeszukiwania du¿ych baz danych zwi¿zków chemicznych w celu wybrania mniejszej liczby zwi¿zków do badä biologicznych. Obiecuj¿ce zwi¿zki s¿ nast¿pnie 'dokowane' do biäka lub aktywnego miejsca enzymu. Algorytmy wyszukiwania dokowania generuj¿ 'pozycje'(konformacj¿, po¿o¿enie i orientacj¿) liganda w aktywnym miejscu, podczas gdy funkcje punktacji identyfikuj¿ najbardziej prawdopodobn¿ pozycj¿ dla poszczególnych ligandów i przypisuj¿ kolejno¿¿ priorytetow¿ zestawowi ró¿nych ligandów dokowanych do tego samego biäka, poprzez oszacowanie powinowactwa wi¿zania. Celem tej ksi¿¿ki jest zapoznanie czytelnika z mo¿liwo¿ciami przesiewania i dokowania ró¿nych ligandów (leków i pestycydów) na powierzchni ró¿nych enzymów. 68 pp. Polnisch.…

PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Virtual screening refers to a range of 'in-silico' techniques used to search large compound databases to select a smaller number of compounds for biological testing. Promising compounds are then 'docked' to the protein or to the enzyme's active site. Docking search algorithms generate 'poses' (conformation, position and orientation) of the ligand within the active site, while scoring functions identify the most likely pose for an individual ligand and assign a priority order to a set of diverse ligands docked to the same protein, by estimate binding affinity. The aim of this book is to acquaint the reader with the possibilities of screening and docking of different ligands (drugs and pesticides) on the surface of different enzymes.…

PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Le criblage virtuel désigne un ensemble de techniques « in silico » utilisées pour effectuer des recherches dans de vastes bases de données de composés afin de sélectionner un nombre plus restreint de composés destinés à des tests biologiques. Les composés prometteurs sont ensuite « arrimés » à la protéine ou au site actif de l'enzyme. Les algorithmes de recherche d'arrimage génèrent des « poses » (conformation, position et orientation) du ligand au sein du site actif, tandis que les fonctions de notation identifient la pose la plus probable pour un ligand individuel et attribuent un ordre de priorité à un ensemble de ligands divers arrimés à la même protéine, en estimant l'affinité de liaison. L'objectif de cet ouvrage est de familiariser le lecteur avec les possibilités de criblage et d'ancrage de différents ligands (médicaments et pesticides) à la surface de différentes enzymes.…

Paperback. Etat : Brand New. 68 pages. Polish language. 6.00x0.16x9.00 inches. In Stock. This item is printed on demand.

Etat : New. Print on Demand.

Etat : New. PRINT ON DEMAND.

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Virtuelles Screening bezeichnet eine Reihe von 'In-silico'-Techniken, die zur Durchsuchung großer Verbindungsdatenbanken verwendet werden, um eine kleinere Anzahl von Verbindungen für biologische Tests auszuwählen. Vielversprechende Verbindungen werden dann an das Protein oder die aktive Stelle des Enzyms 'angedockt'. Docking-Suchalgorithmen generieren 'Posen' (Konformation,Position und Ausrichtung) des Liganden innerhalb der aktiven Stelle, während Bewertungsfunktionen die wahrscheinlichste Pose für einen einzelnen Liganden identifizieren und einer Reihe verschiedener Liganden, die an dasselbe Protein angedockt sind, eine Prioritätsreihenfolge zuweisen, indem sie die Bindungsaffinität schätzen. Das Ziel dieses Buches ist es, den Leser mit den Möglichkeiten des Screenings und Docking verschiedener Liganden (Arzneimittel und Pestizide) auf der Oberfläche verschiedener Enzyme vertraut zu machen.…

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Lo screening virtuale si riferisce a una serie di tecniche 'in silico' utilizzate per cercare in grandi database di composti al fine di selezionare un numero più ristretto di composti da sottoporre a test biologici. I composti promettenti vengono quindi 'agganciati' alla proteina o al sito attivo dell'enzima. Gli algoritmi di ricerca di aggancio generano 'pose' (conformazione, posizione e orientamento) del ligando all'interno del sito attivo, mentre le funzioni di punteggio identificano la posa più probabile per un singolo ligando e assegnano un ordine di priorità a una serie di ligandi diversi agganciati alla stessa proteina, stimando l'affinità di legame. Lo scopo di questo libro è quello di familiarizzare il lettore con le possibilità di screening e docking di diversi ligandi (farmaci e pesticidi) sulla superficie di diversi enzimi.…

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A triagem virtual refere-se a uma série de técnicas 'in silico' utilizadas para pesquisar grandes bases de dados de compostos, a fim de selecionar um número menor de compostos para testes biológicos. Os compostos promissores são então 'acoplados' à proteína ou ao sítio ativo da enzima. Os algoritmos de pesquisa de acoplamento geram 'poses' (conformação, posição e orientação) do ligante dentro do sítio ativo, enquanto as funções de pontuação identificam a pose mais provável para um ligante individual e atribuem uma ordem de prioridade a um conjunto de diversos ligantes acoplados à mesma proteína, por estimativa da afinidade de ligação. O objetivo deste livro é familiarizar o leitor com as possibilidades de triagem e acoplamento de diferentes ligantes (medicamentos e pesticidas) na superfície de diferentes enzimas.…