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Hardcover. Etat : Near Fine. 3764358181. Pictorial board hardcover, from closed pharmaceutical company library. 152 pages, refs, index, illustrated with charts, tables and diagrams. Summarizes the state of information on chemokines focussing on skin diseases. Contents clean, tight and bright. Book.

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Etat : New. pp. 156.

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The accumulation of white blood cells is a hallmark of inflammation. The penetra tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber [1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a [2] and the arachidonic acid metabolite leukotriene B4 [3]. In 1986, a novel human monocyte-derived chemo taxin attracting neutrophilic granulocytes with a similar potency was found [4]. This report was quickly confirmed by several groups [5-8]. The new factor was purified, cloned and sequenced [9, 10]. The term 'interleukin 8' (IL-8) replaced the various names proposed previously [4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called 'chemokines' [11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig nated accordingly as C, CC, CXC and CX C chemokines [11-13]. The number of 3 human chemokines identified so far is close to 40 [11-13].…

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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The present volume summarizes the state of information on chemokines focussing on skin diseases. The first three chapters deal with the structure and molecular biology of chemokines and their receptors. The following three review information on the interaction of chemokines with lymphocytes, mast cells and eosinophilic granulocytes. One chapter deals with the expression of chemokines in several inflammatory skin diseases. The final chapter reports on in vitro evidence for a growth-promoting activity of chemokines in skin-derived tumor cells. The volume is of use for the basic scientist interested in practical aspects and for the physician in search for basic mechanisms of skin diseases.…

Hardcover. Etat : Brand New. 156 pages. 6.69x0.44x9.61 inches. In Stock.

Etat : New. The present volume summarizes the state of information on chemokines focussing on skin diseases. The first three chapters deal with the structure and molecular biology of chemokines and their receptors. The following three review information on the interact.

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The accumulation of white blood cells is a hallmark of inflammation. The penetra tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber [1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a [2] and the arachidonic acid metabolite leukotriene B4 [3]. In 1986, a novel human monocyte-derived chemo taxin attracting neutrophilic granulocytes with a similar potency was found [4]. This report was quickly confirmed by several groups [5-8]. The new factor was purified, cloned and sequenced [9, 10]. The term 'interleukin 8' (IL-8) replaced the various names proposed previously [4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called 'chemokines' [11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig nated accordingly as C, CC, CXC and CX C chemokines [11-13]. The number of 3 human chemokines identified so far is close to 40 [11-13]. 156 pp. Englisch.…

Etat : New. Print on Demand pp. 156.

Etat : New. PRINT ON DEMAND pp. 156.

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-c.…

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present volume summarizes the state of information on chemokines focussing on skin diseases. The first three chapters deal with the structure and molecular biology of chemokines and their receptors. The following three review information on the interaction of chemokines with lymphocytes, mast cells and eosinophilic granulocytes. One chapter deals with the expression of chemokines in several inflammatory skin diseases. The final chapter reports on in vitro evidence for a growth-promoting activity of chemokines in skin-derived tumor cells. The volume is of use for the basic scientist interested in practical aspects and for the physician in search for basic mechanisms of skin diseases. 138 pp. Englisch.…

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-chemokines - autocrine growth factors for melanoma and epidermoid carcinoma cells.- Expression of chemokines in dermatoses.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 156 pp. Englisch.…