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Trade Paperback. Etat : Good. This trade paperback is in good condition, showing minor wear consistent with age and handling. The cover is intact with some light creasing visible, but no tears or significant damage. The spine is strong and the pages are clean, free of any inscriptions or annotations. There are no library stamps or markings present. not applicable (trade paperback) Expanded edition published October, 1988.…

Etat : Very Good. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Etat : As New. Unread book in perfect condition.

Etat : New.

Etat : New. pp. 328.

Paperback. Etat : Brand New. 328 pages. 9.25x6.10x0.74 inches. In Stock.

Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Since their introduction to medical practice in 1960, benzodiazepines have become among the most commonly prescribed medications and have, to a great extent, replaced prescriptions of short-acting barbiturates and other sedative-hypnotics. The discovery of their psychoactive properties was almost missed. During a cleaning of their laboratory in April of 1957, Earl Reeder called to Leo Sternbach's attention several hundred milligrams of a substance and its hydrochloride salt they had synthesized in 1955 which had not been submitted for pharmacological testing. They sent the hydrochlor ide salt, later given the generic designation of chlordiazepoxide (Librium), for animal testing to the pharmacology department, which was under the direction of Lowell Randall. Six tests, used for preliminary screening of tranquilizers and sedatives, were conducted. Dr. Randall phoned Dr. Sternbach a few days later to report that the compound possessed interesting psychotropic properties in animals (Sternback. 1983). Subse quently over 3000 1,4 benzo-and heterodiazepines have been synthesized (Sternbach, 1983). and more is known about the mechanism of action of this class of medications than any other psychotropic drug class (Haefely, 1983). Used for treatment of anxiety. insomnia. muscle spasticity, convulsive disorders, anesthesia adjuncts and alcohol detoxification. the benzodiazepines have significant advantages over their predecessor medi cations: the short-acting barbiturates, meprobamate and methaqualone. Of significance is their high lethal/therapeutic ratio. of importance in cases of overdose; their failure to activate liver microsomal enzymes.…

hardcover. Etat : Good. Ships Out Tomorrow.

Etat : Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.…

Etat : new. Questo è un articolo print on demand.

PF. Etat : New. This item is printed on demand. Brand new book, sourced directly from publisher. Dispatch time is 6-7 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since their introduction to medical practice in 1960, benzodiazepines have become among the most commonly prescribed medications and have, to a great extent, replaced prescriptions of short-acting barbiturates and other sedative-hypnotics. The discovery of their psychoactive properties was almost missed. During a cleaning of their laboratory in April of 1957, Earl Reeder called to Leo Sternbach's attention several hundred milligrams of a substance and its hydrochloride salt they had synthesized in 1955 which had not been submitted for pharmacological testing. They sent the hydrochlor ide salt, later given the generic designation of chlordiazepoxide (Librium), for animal testing to the pharmacology department, which was under the direction of Lowell Randall. Six tests, used for preliminary screening of tranquilizers and sedatives, were conducted. Dr. Randall phoned Dr. Sternbach a few days later to report that the compound possessed interesting psychotropic properties in animals (Sternback. 1983). Subse quently over 3000 1,4 benzo-and heterodiazepines have been synthesized (Sternbach, 1983). and more is known about the mechanism of action of this class of medications than any other psychotropic drug class (Haefely, 1983). Used for treatment of anxiety. insomnia. muscle spasticity, convulsive disorders, anesthesia adjuncts and alcohol detoxification. the benzodiazepines have significant advantages over their predecessor medi cations: the short-acting barbiturates, meprobamate and methaqualone. Of significance is their high lethal/therapeutic ratio. of importance in cases of overdose; their failure to activate liver microsomal enzymes. 328 pp. Englisch.…

Etat : New. Print on Demand pp. 328 Illus.

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. I Clinical Pharmacology.- 1 The biological basis of benzodiazepine actions.- 2 Clinical pharmacokinetics of the benzodiazepines.- 3 Pharmacokinetic considerations in the treatment of chronic anxiety.- II Therapeutic Application.- 4 An international overview.…

Etat : New. PRINT ON DEMAND pp. 328.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -I Clinical Pharmacology.- 1 The biological basis of benzodiazepine actions.- 2 Clinical pharmacokinetics of the benzodiazepines.- 3 Pharmacokinetic considerations in the treatment of chronic anxiety.- II Therapeutic Application.- 4 An international overview.- 5 Principles of therapeutic applications of benzodiazepines.- 6 Benzodiazepines in emotional disorders.- 7 Anxiety.- 8 Clinical comparison of benzodiazepine hypnotics with short and long elimination half-lives.- 9 Seizure disorders.- 10 Alcohol and other drug withdrawals.- 11 Additional clinical uses of benzodiazepines.- 12 Vital uses of diazepam in third world countries.- III Non-medical Use, Misuse and Abuse.- 13 Abuse and dependency: an international perspective.- 14 Experimental abuse liability assessment of benzodiazepines.- 15 Abuse liability of benzodiazepines: A review of human studies evaluating subjective and/or reinforcing effects.- 16 Acute and chronic toxicity of benzodiazepines.- IV Dependence.- 17 Benzodiazepine dependency syndromes.- V Social-Cultural Issues.- 18 The benzodiazepines: public health, social and regulatory issues. An industry perspective.- 19 Benzodiazepines: international legislation and relation to the Convention on Psychotropic Substances 1971.- Appendices.- 1 Cross-reference of investigational, generic and trade names.- 2 Books on benzodiazepines.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 328 pp. Englisch.…