ISBN: 9783659832321 - plasmid segregational instability in recombinant e.coli fermentations: modeling aspects of macromixing and plasmid loss probability in batch and continuous e.coli fermentations (7 résultats)

Paperback. Etat : Brand New. 72 pages. 8.66x5.91x0.17 inches. In Stock.

Taschenbuch. Etat : Neu. Plasmid Segregational Instability in Recombinant [.] Fermentations | Modeling aspects of Macromixing and Plasmid loss probability in Batch and Continuous [.] Fermentations | G. V. S. Rama Krishna | Taschenbuch | 72 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659832321 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.…

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Segregational instability of plasmids in genetically altered Escherichia coli bacteria is not suitable for successful production of recombinant products. In this study, Escherichia coli C600 galK containing the plasmid pBR Eco gap, which codes for glyceraldehyde-3-phosphate dehydrogenase (GAPDH), was studied under industrial conditions for GAPDH production. Detailed mathematical models were developed for batch and continuous fermentations by introducing non-ideality through imperfect mixing, variable plasmid loss probability, and simulated for both fermenters by regulating mixing intensities (as a function of dilution rates). Effect of finite macromixing and a variable plasmid loss probability on plasmid stability, substrate utilization and product formation were explored by inserting generalized plasmid replication kinetics into an experimentally validated macromixing model. 72 pp. Englisch.…

Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Segregational instability of plasmids in genetically altered Escherichia coli bacteria is not suitable for successful production of recombinant products. In this study, Escherichia coli C600 galK containing the plasmid pBR Eco gap, which codes for glyceraldehyde-3-phosphate dehydrogenase (GAPDH), was studied under industrial conditions for GAPDH production. Detailed mathematical models were developed for batch and continuous fermentations by introducing non-ideality through imperfect mixing, variable plasmid loss probability, and simulated for both fermenters by regulating mixing intensities (as a function of dilution rates). Effect of finite macromixing and a variable plasmid loss probability on plasmid stability, substrate utilization and product formation were explored by inserting generalized plasmid replication kinetics into an experimentally validated macromixing model.…

Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Rama Krishna G.V.S.G.V.S.Rama Krishna currently works as Professor (Assistant), Biotechnology in K.L.University. He holds B.Tech.(Chemical Engg.) from N.I.T,Warangal and M.Tech.(Biotechnology) from Anna University, Chennai. Prof.G.V.…

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Segregational instability of plasmids in genetically altered Escherichia coli bacteria is not suitable for successful production of recombinant products. In this study, Escherichia coli C600 galK containing the plasmid pBR Eco gap, which codes for glyceraldehyde-3-phosphate dehydrogenase (GAPDH), was studied under industrial conditions for GAPDH production. Detailed mathematical models were developed for batch and continuous fermentations by introducing non-ideality through imperfect mixing, variable plasmid loss probability, and simulated for both fermenters by regulating mixing intensities (as a function of dilution rates). Effect of finite macromixing and a variable plasmid loss probability on plasmid stability, substrate utilization and product formation were explored by inserting generalized plasmid replication kinetics into an experimentally validated macromixing model.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Englisch.…